Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.007 0.184 0.339 1.0 -0.619 4.0 5.0 MAP3K8 0.025 0.011 -9999.0 0.0 -9999.0 0.0 0.0 FOS 0.01 0.159 0.307 2.0 -0.528 4.0 6.0 PRKCA 0.022 0.014 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.005 0.101 -9999.0 0.0 -0.326 5.0 5.0 HRAS 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.022 0.015 -9999.0 0.0 -9999.0 0.0 0.0 NRAS 0.026 0.009 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.047 0.022 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.012 0.106 -9999.0 0.0 -0.444 3.0 3.0 MAP2K1 0.026 0.038 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.023 0.019 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.01 0.011 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.003 -9999.0 0.0 -0.007 5.0 5.0 MAPK1 -0.015 0.161 -9999.0 0.0 -0.507 5.0 5.0 RAF1 0.012 0.011 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0