Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.055 0.24 -9999.0 0.0 -0.537 17.0 17.0 MAP3K8 0.02 0.046 -9999.0 0.0 -0.446 1.0 1.0 FOS -0.052 0.209 -9999.0 0.0 -0.493 17.0 17.0 PRKCA 0.025 0.011 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.067 0.17 -9999.0 0.0 -0.333 28.0 28.0 HRAS 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.003 0.099 -9999.0 0.0 -0.288 10.0 10.0 NRAS 0.023 0.011 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.038 0.024 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.04 0.176 -9999.0 0.0 -0.432 17.0 17.0 MAP2K1 0.021 0.093 -9999.0 0.0 -0.452 3.0 3.0 ELK1 0.025 0.013 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.001 0.066 -9999.0 0.0 -0.376 3.0 3.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.003 20.0 20.0 MAPK1 -0.053 0.198 -9999.0 0.0 -0.457 19.0 19.0 RAF1 0.001 0.075 -9999.0 0.0 -0.371 4.0 4.0 KRAS 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0