Clinical Features Time to Death AGE GENDER KARNOFSKY.PERFORMANCE.SCORE HISTOLOGICAL.TYPE PATHOLOGY.T PATHOLOGY.N PATHOLOGICSPREAD(M) TUMOR.STAGE RADIATIONS.RADIATION.REGIMENINDICATION NUMBERPACKYEARSSMOKED STOPPEDSMOKINGYEAR TOBACCOSMOKINGHISTORYINDICATOR YEAROFTOBACCOSMOKINGONSET nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q Amp Peak 1(1p34.3) 95 (29%) 232 0.91053 1 0.0092728 1 0.80805 1 0.42075 1 0.49788 1 0.73037 1 0.21929 1 0.8546 1 0.58322 1 0.45206 1 0.88833 1 0.60006 1 0.056488 1 0.80238 1 Amp Peak 2(1p22.3) 92 (28%) 235 0.75476 1 0.00065965 0.686 1 1 0.6086 1 0.11993 1 0.88588 1 0.058509 1 0.43169 1 0.28389 1 0.45354 1 0.40311 1 0.38785 1 0.54668 1 0.44436 1 Amp Peak 3(1q21.3) 239 (73%) 88 0.33392 1 0.28166 1 0.060141 1 0.31141 1 0.025465 1 0.69577 1 0.84533 1 0.85201 1 0.90038 1 0.30012 1 0.62619 1 0.56975 1 0.23705 1 0.29501 1 Amp Peak 4(3q26.2) 118 (36%) 209 0.89167 1 0.44423 1 1 1 0.72596 1 0.84472 1 0.75488 1 0.23758 1 0.38434 1 0.56716 1 0.34375 1 0.14223 1 0.024351 1 0.01662 1 0.092192 1 Amp Peak 5(4q12) 66 (20%) 261 0.2248 1 0.0098058 1 0.78305 1 0.90175 1 0.29394 1 0.087614 1 0.43875 1 0.48045 1 0.59584 1 0.77492 1 0.98713 1 0.59476 1 0.96494 1 0.24601 1 Amp Peak 6(5p15.33) 215 (66%) 112 0.19429 1 0.0044919 1 0.0099457 1 0.026303 1 0.15844 1 0.12673 1 0.54527 1 0.4508 1 0.49338 1 0.46964 1 0.19451 1 0.026345 1 0.13912 1 0.19916 1 Amp Peak 7(5p13.2) 199 (61%) 128 0.041494 1 0.010548 1 0.012582 1 0.99682 1 0.19641 1 0.12273 1 0.3438 1 0.75231 1 0.47117 1 0.8151 1 0.11398 1 0.0082166 1 0.19659 1 0.25547 1 Amp Peak 8(5p12) 189 (58%) 138 0.067486 1 0.002513 1 0.018658 1 0.86666 1 0.14298 1 0.14084 1 0.55387 1 0.16437 1 0.32095 1 1 1 0.1961 1 0.037222 1 0.14011 1 0.29847 1 Amp Peak 9(5q35.1) 79 (24%) 248 0.10176 1 0.28962 1 0.02726 1 0.97064 1 0.50642 1 0.39153 1 0.58632 1 0.76969 1 0.64045 1 0.58985 1 0.55293 1 0.4505 1 0.061025 1 0.14803 1 Amp Peak 10(6p25.3) 130 (40%) 197 0.51869 1 0.20595 1 0.42727 1 0.86285 1 0.44359 1 0.57008 1 0.017786 1 0.33117 1 0.094332 1 0.35347 1 0.52652 1 0.57094 1 0.096891 1 0.40737 1 Amp Peak 11(6p21.1) 120 (37%) 207 0.64771 1 0.41716 1 0.24952 1 0.92355 1 0.77909 1 0.52414 1 0.097267 1 0.2035 1 0.54104 1 0.6356 1 0.78625 1 0.60828 1 0.030872 1 0.62355 1 Amp Peak 12(7p15.3) 179 (55%) 148 0.7341 1 0.42956 1 0.37473 1 0.90794 1 0.38885 1 0.23313 1 0.10452 1 0.71352 1 0.36186 1 0.81734 1 0.4215 1 0.69978 1 0.031025 1 0.61154 1 Amp Peak 13(7p11.2) 172 (53%) 155 0.18019 1 0.11256 1 0.43643 1 0.69487 1 0.32227 1 0.12922 1 0.0071224 1 0.77611 1 0.15784 1 0.82176 1 0.60587 1 0.5526 1 0.0496 1 0.10109 1 Amp Peak 14(7q31.2) 136 (42%) 191 0.97639 1 0.055245 1 0.73667 1 0.37565 1 0.55481 1 0.37588 1 0.18555 1 0.39997 1 0.35307 1 0.24492 1 0.42906 1 0.23132 1 0.31265 1 0.98367 1 Amp Peak 15(8p11.21) 108 (33%) 219 0.47774 1 0.04243 1 0.034 1 0.19431 1 0.064836 1 0.98513 1 0.10636 1 0.64065 1 0.24331 1 0.81118 1 0.70062 1 0.62767 1 0.026152 1 0.85374 1 Amp Peak 16(8q11.1) 148 (45%) 179 0.82991 1 0.026134 1 0.65722 1 0.91286 1 0.15978 1 0.71476 1 0.34292 1 0.61517 1 0.50516 1 1 1 0.2968 1 0.43401 1 0.017149 1 0.11632 1 Amp Peak 17(8q24.21) 208 (64%) 119 0.44166 1 0.11094 1 0.35725 1 0.8848 1 0.072362 1 0.35498 1 0.57702 1 0.93338 1 0.76833 1 0.63645 1 0.7951 1 0.48147 1 0.062126 1 0.57781 1 Amp Peak 18(11q13.3) 114 (35%) 213 0.80435 1 2.7431e-05 0.0287 0.24377 1 0.51865 1 0.62269 1 0.69543 1 0.78837 1 0.53554 1 0.14936 1 0.8097 1 0.91244 1 0.079205 1 0.010736 1 0.57608 1 Amp Peak 19(12p12.1) 118 (36%) 209 0.036146 1 0.29952 1 0.81717 1 0.8207 1 0.59826 1 0.56012 1 0.75878 1 0.38227 1 0.86573 1 0.81082 1 0.84881 1 0.24099 1 0.08858 1 0.21838 1 Amp Peak 20(12q14.1) 106 (32%) 221 0.18768 1 0.074418 1 0.6371 1 0.55822 1 0.80618 1 0.56673 1 0.74825 1 0.44524 1 0.37611 1 1 1 0.40792 1 0.00059823 0.623 0.050405 1 0.0010154 1 Amp Peak 21(12q15) 109 (33%) 218 0.44872 1 0.21339 1 0.72453 1 0.32128 1 0.82769 1 0.77696 1 0.53187 1 0.72087 1 0.66779 1 1 1 0.2374 1 0.026026 1 0.029998 1 0.0032645 1 Amp Peak 22(13q33.3) 54 (17%) 273 0.89646 1 0.82053 1 0.13418 1 NA NA 0.93382 1 0.4232 1 0.49167 1 0.63372 1 0.69533 1 1 1 0.39227 1 0.84501 1 0.66294 1 0.96733 1 Amp Peak 23(14q13.3) 144 (44%) 183 0.50222 1 0.46849 1 0.6554 1 0.59187 1 0.53545 1 0.62852 1 0.90931 1 0.1926 1 0.64444 1 1 1 0.8731 1 0.018528 1 0.17136 1 0.019148 1 Amp Peak 24(17q12) 148 (45%) 179 0.90429 1 0.87942 1 0.82441 1 0.098111 1 0.59245 1 0.49266 1 0.52297 1 0.35303 1 0.55106 1 0.10258 1 0.01592 1 0.073652 1 0.22369 1 0.69189 1 Amp Peak 25(17q23.1) 160 (49%) 167 0.56064 1 0.33467 1 0.65681 1 0.59121 1 0.1768 1 0.31086 1 0.4012 1 0.38824 1 0.61229 1 0.648 1 0.065901 1 0.02611 1 0.13278 1 0.37223 1 Amp Peak 26(18q11.2) 73 (22%) 254 0.70175 1 0.27975 1 0.68919 1 0.75249 1 0.23401 1 0.81374 1 0.38746 1 0.48465 1 0.75911 1 0.26648 1 0.28011 1 0.47489 1 0.060372 1 0.79782 1 Amp Peak 27(19q12) 91 (28%) 236 0.70618 1 0.60085 1 0.10717 1 0.25859 1 0.40857 1 0.43618 1 0.65982 1 0.92553 1 0.57048 1 0.30146 1 0.43495 1 0.013666 1 0.79137 1 0.27798 1 Amp Peak 28(20q13.33) 160 (49%) 167 0.43978 1 0.41974 1 0.82419 1 0.27394 1 0.11902 1 0.12844 1 0.18595 1 0.099801 1 0.034477 1 0.49182 1 0.36068 1 0.11866 1 0.16503 1 0.86551 1 Amp Peak 29(22q11.22) 54 (17%) 273 0.29893 1 0.48925 1 0.36962 1 NA NA 0.42376 1 0.44418 1 0.43456 1 0.045676 1 0.23648 1 1 1 0.85535 1 0.62076 1 0.70969 1 0.57446 1 Amp Peak 30(Xq28) 113 (35%) 214 0.19464 1 0.19142 1 0.19894 1 0.28784 1 0.38227 1 0.57725 1 0.33034 1 0.5199 1 0.45968 1 1 1 0.27267 1 0.93012 1 0.050768 1 0.93699 1 Del Peak 1(1p36.13) 77 (24%) 250 0.035597 1 0.59798 1 0.067552 1 0.4475 1 0.6684 1 0.092556 1 0.071205 1 0.47264 1 0.077863 1 0.5857 1 0.94103 1 0.68234 1 0.42604 1 0.7503 1 Del Peak 2(1p13.1) 99 (30%) 228 0.67048 1 0.14287 1 0.54612 1 0.74594 1 0.70409 1 0.38162 1 0.59743 1 0.62329 1 0.13487 1 1 1 0.35705 1 0.58207 1 0.78653 1 0.58055 1 Del Peak 3(2q22.1) 37 (11%) 290 0.8604 1 0.59057 1 1 1 0.90089 1 0.24754 1 0.18101 1 0.63563 1 0.26137 1 0.13746 1 1 1 0.12434 1 0.07744 1 0.086111 1 0.57891 1 Del Peak 4(2q37.3) 54 (17%) 273 0.39728 1 0.88933 1 0.071939 1 0.56077 1 0.099411 1 0.82322 1 0.07397 1 0.25333 1 0.55033 1 0.054854 1 0.84271 1 0.84576 1 0.19538 1 0.40343 1 Del Peak 5(3p21.31) 163 (50%) 164 0.5695 1 0.40489 1 0.5791 1 0.063787 1 0.57882 1 0.0071183 1 0.030967 1 0.44177 1 0.13998 1 0.24814 1 0.74305 1 0.023299 1 0.015987 1 5.0685e-05 0.053 Del Peak 6(3q11.1) 97 (30%) 230 0.42521 1 0.10669 1 0.39484 1 0.082433 1 0.95943 1 0.81836 1 0.86758 1 0.8843 1 0.55909 1 0.8023 1 0.13734 1 0.70476 1 0.87117 1 0.015903 1 Del Peak 7(3q29) 95 (29%) 232 0.75893 1 0.55849 1 0.80805 1 0.36745 1 0.58741 1 0.46976 1 0.13353 1 0.60095 1 0.12116 1 0.45206 1 0.18919 1 0.69583 1 0.68559 1 0.15325 1 Del Peak 8(4q35.1) 120 (37%) 207 0.75625 1 0.14248 1 0.2059 1 0.18823 1 0.089463 1 0.18889 1 0.28691 1 0.19414 1 0.28279 1 0.23407 1 0.47509 1 0.089787 1 0.0015735 1 0.19388 1 Del Peak 9(5q11.2) 117 (36%) 210 0.37447 1 0.046506 1 1 1 0.47026 1 0.44369 1 0.43737 1 0.07881 1 0.44022 1 0.3017 1 0.34561 1 0.13629 1 0.00021812 0.228 0.08858 1 0.21904 1 Del Peak 10(5q33.1) 118 (36%) 209 0.25538 1 0.0026937 1 0.72974 1 0.9367 1 0.23433 1 0.26588 1 0.049609 1 0.9338 1 0.14701 1 0.15218 1 0.078646 1 0.00065464 0.681 2.0794e-05 0.0218 0.019573 1 Del Peak 11(6q12) 116 (35%) 211 0.16955 1 0.77609 1 0.24555 1 0.19239 1 0.3499 1 0.71131 1 0.05703 1 0.44319 1 0.049754 1 0.4697 1 0.019281 1 0.49488 1 0.022572 1 0.09778 1 Del Peak 12(6q22.31) 168 (51%) 159 0.45639 1 0.36524 1 1 1 0.18945 1 0.90776 1 0.6792 1 0.72522 1 0.44047 1 0.41441 1 1 1 0.19028 1 0.086858 1 0.1535 1 0.45201 1 Del Peak 13(6q26) 171 (52%) 156 0.52413 1 0.17133 1 0.73968 1 0.2708 1 0.86835 1 0.96148 1 0.46533 1 0.10219 1 0.15579 1 1 1 0.726 1 0.14616 1 0.37151 1 0.30291 1 Del Peak 14(8p23.2) 164 (50%) 163 0.69172 1 0.29315 1 0.26742 1 0.044627 1 0.011837 1 0.38182 1 0.81835 1 0.93935 1 0.87063 1 0.48973 1 0.76321 1 0.87426 1 0.041052 1 0.23463 1 Del Peak 15(8p21.3) 175 (54%) 152 0.23971 1 0.9776 1 0.11959 1 0.049446 1 0.011426 1 0.58627 1 0.4512 1 0.31852 1 0.9078 1 0.64648 1 0.28035 1 0.2891 1 0.13228 1 0.49532 1 Del Peak 16(9p23) 180 (55%) 147 0.061433 1 0.093606 1 0.73908 1 0.6137 1 0.74983 1 0.85589 1 0.011587 1 0.71352 1 0.35573 1 0.4875 1 0.84774 1 0.035563 1 0.071506 1 0.27674 1 Del Peak 17(9p21.3) 187 (57%) 140 0.37358 1 0.032687 1 0.11604 1 0.8207 1 0.83082 1 0.94066 1 0.002825 1 0.75623 1 0.087354 1 1 1 0.45973 1 0.0042678 1 0.15198 1 0.18937 1 Del Peak 18(9q21.11) 160 (49%) 167 0.22246 1 0.71387 1 0.65681 1 0.90804 1 0.047121 1 0.38572 1 0.38514 1 0.73018 1 0.43018 1 0.10584 1 0.065564 1 0.90091 1 0.32418 1 0.76921 1 Del Peak 19(10p15.3) 81 (25%) 246 0.15444 1 0.53656 1 5.8073e-05 0.0607 0.85084 1 0.46332 1 0.3932 1 0.66245 1 0.37054 1 0.8304 1 0.79122 1 0.53897 1 0.58015 1 0.0044639 1 0.75052 1 Del Peak 20(10q26.3) 90 (28%) 237 0.66495 1 0.89731 1 0.034516 1 0.23586 1 0.66634 1 0.06392 1 0.45475 1 0.97475 1 0.19757 1 0.075482 1 0.026927 1 0.83992 1 0.025692 1 0.066835 1 Del Peak 21(11p15.5) 88 (27%) 239 0.51817 1 0.072155 1 0.31782 1 0.31815 1 0.28697 1 1 1 1 1 0.061391 1 0.32555 1 1 1 0.32507 1 0.71495 1 0.014911 1 0.13066 1 Del Peak 22(11q24.1) 77 (24%) 250 0.25579 1 0.13456 1 0.79429 1 0.18571 1 0.71635 1 0.91328 1 0.15381 1 0.26634 1 0.46237 1 0.42818 1 0.40897 1 0.43217 1 0.7488 1 0.51397 1 Del Peak 23(11q25) 73 (22%) 254 0.26009 1 0.52263 1 0.50495 1 0.53452 1 0.72225 1 0.74192 1 0.21492 1 0.44112 1 0.73276 1 0.58228 1 0.34907 1 0.90147 1 0.34736 1 0.15229 1 Del Peak 24(12p13.2) 92 (28%) 235 0.28268 1 0.81527 1 0.0019833 1 0.82637 1 0.71489 1 0.85542 1 0.83542 1 0.27784 1 0.4295 1 0.80239 1 0.0074096 1 0.62896 1 0.41001 1 0.05224 1 Del Peak 25(12q12) 68 (21%) 259 0.043262 1 0.21756 1 0.039879 1 0.69255 1 0.26215 1 0.92687 1 0.37271 1 0.027163 1 0.66002 1 0.77596 1 0.085685 1 0.72884 1 0.94454 1 0.3864 1 Del Peak 26(12q24.33) 80 (24%) 247 0.48798 1 0.83039 1 0.19746 1 0.39223 1 0.085086 1 0.06646 1 0.8985 1 0.4132 1 0.69208 1 0.17806 1 0.18965 1 0.86087 1 0.015358 1 0.37566 1 Del Peak 27(13q12.11) 180 (55%) 147 0.60623 1 0.13071 1 0.010504 1 0.025228 1 0.026143 1 0.56194 1 0.98658 1 0.34254 1 0.83926 1 0.36446 1 0.031831 1 0.20635 1 0.01346 1 0.18024 1 Del Peak 28(13q12.13) 181 (55%) 146 0.72162 1 0.30977 1 0.045041 1 0.039932 1 0.010766 1 0.72359 1 0.885 1 0.34254 1 0.85812 1 0.16998 1 0.12704 1 0.65767 1 0.055182 1 0.17612 1 Del Peak 29(13q34) 147 (45%) 180 0.77075 1 0.10316 1 0.82332 1 0.66855 1 0.29945 1 0.63605 1 0.98658 1 0.11929 1 0.30568 1 1 1 0.49717 1 0.27535 1 0.082221 1 0.12108 1 Del Peak 30(14q32.13) 96 (29%) 231 0.41487 1 0.55879 1 0.90349 1 0.78616 1 0.66636 1 0.38594 1 0.10852 1 0.55836 1 0.2968 1 0.31305 1 0.20427 1 0.82255 1 0.52878 1 0.061696 1 Del Peak 31(15q11.2) 171 (52%) 156 0.32414 1 0.089758 1 0.045182 1 0.24143 1 0.11574 1 0.24616 1 0.96055 1 0.97906 1 0.56226 1 1 1 0.37293 1 0.20704 1 0.25358 1 0.18844 1 Del Peak 32(15q15.3) 177 (54%) 150 0.4337 1 0.12877 1 0.11983 1 0.24143 1 0.01834 1 0.39741 1 0.9866 1 0.95856 1 0.89825 1 0.64876 1 0.80068 1 0.16729 1 0.11428 1 0.24683 1 Del Peak 33(16q23.1) 112 (34%) 215 0.96081 1 0.61616 1 0.64 1 0.5913 1 0.50774 1 0.67349 1 0.48197 1 0.84887 1 0.73947 1 1 1 0.57398 1 0.41137 1 0.096507 1 0.92828 1 Del Peak 34(17p13.3) 188 (57%) 139 0.64174 1 0.15994 1 0.17925 1 0.77821 1 0.049334 1 0.23721 1 0.90828 1 0.70629 1 0.82626 1 0.25345 1 0.41774 1 0.48193 1 0.12109 1 0.0086888 1 Del Peak 35(17p11.2) 158 (48%) 169 0.12749 1 0.07121 1 0.22409 1 0.16159 1 0.16862 1 0.030269 1 0.18316 1 0.21799 1 0.56025 1 0.1083 1 0.969 1 0.86718 1 0.056409 1 0.07028 1 Del Peak 36(18q21.32) 170 (52%) 157 0.24412 1 0.33993 1 0.095222 1 0.30054 1 0.70336 1 0.26603 1 0.16891 1 0.069941 1 0.045826 1 1 1 0.4942 1 0.85518 1 0.25026 1 0.15158 1 Del Peak 37(19p13.3) 184 (56%) 143 0.048902 1 0.28295 1 0.0024852 1 0.80204 1 0.46935 1 0.241 1 0.15716 1 0.46292 1 0.017413 1 0.81851 1 0.50134 1 0.58391 1 0.15163 1 0.24516 1 Del Peak 38(19p13.2) 177 (54%) 150 0.36071 1 0.041068 1 0.0011931 1 0.92285 1 0.59487 1 0.26415 1 0.093047 1 0.13881 1 0.030566 1 0.81789 1 0.45881 1 0.46976 1 0.037205 1 0.22816 1 Del Peak 39(19p12) 142 (43%) 185 0.012803 1 0.010814 1 0.033374 1 0.96228 1 0.81501 1 0.042035 1 0.010455 1 0.22308 1 0.00030431 0.317 1 1 0.17914 1 0.93423 1 0.11588 1 0.18111 1 Del Peak 40(19q13.33) 123 (38%) 204 0.038427 1 0.19303 1 0.35929 1 0.46539 1 0.18701 1 0.55722 1 0.5908 1 0.16727 1 0.14564 1 0.81573 1 0.45034 1 0.90176 1 0.25784 1 0.5128 1 Del Peak 41(21q11.2) 116 (35%) 211 0.61898 1 0.0607 1 0.90819 1 0.75054 1 0.39067 1 0.70472 1 0.91638 1 0.9132 1 0.78043 1 0.4697 1 0.13337 1 0.050186 1 0.015808 1 0.013118 1 Del Peak 42(21q21.3) 113 (35%) 214 0.51157 1 0.22907 1 0.19894 1 0.535 1 0.71768 1 0.69916 1 0.91508 1 0.56269 1 0.6345 1 0.33676 1 0.05133 1 0.024432 1 0.0026468 1 0.14922 1 Del Peak 43(22q13.32) 160 (49%) 167 0.47493 1 0.019961 1 0.22347 1 0.53651 1 0.36235 1 0.76244 1 0.67746 1 0.71428 1 0.72092 1 0.81904 1 0.502 1 0.11166 1 0.0010858 1 0.0059115 1 Del Peak 44(Xp22.2) 96 (29%) 231 0.55994 1 0.66573 1 0.039013 1 0.93062 1 0.6531 1 0.91252 1 0.42827 1 0.79482 1 0.89404 1 0.80256 1 0.64037 1 0.65054 1 0.62427 1 0.16993 1 Del Peak 45(Xp21.3) 93 (28%) 234 0.75325 1 0.85743 1 0.06449 1 0.93062 1 0.79933 1 0.8417 1 0.63446 1 0.74944 1 0.8997 1 1 1 0.30065 1 0.50885 1 0.89855 1 0.057995 1