Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.095 0.209 0.508 66.0 -9999.0 0.0 66.0 KIRREL -0.034 0.167 -9999.0 0.0 -0.727 19.0 19.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.095 0.209 -9999.0 0.0 -0.509 66.0 66.0 PLCG1 0.01 0.03 -9999.0 0.0 -0.546 1.0 1.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.071 0.16 -9999.0 0.0 -0.459 38.0 38.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.031 0.136 -9999.0 0.0 -0.379 38.0 38.0 FYN -0.054 0.162 -9999.0 0.0 -0.447 39.0 39.0 mol:Ca2+ -0.072 0.158 -9999.0 0.0 -0.451 39.0 39.0 mol:DAG -0.072 0.159 -9999.0 0.0 -0.454 39.0 39.0 NPHS2 -0.01 0.026 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.072 0.159 -9999.0 0.0 -0.454 39.0 39.0 regulation of endocytosis -0.044 0.154 -9999.0 0.0 -0.417 39.0 39.0 Nephrin/NEPH1/podocin/Cholesterol -0.073 0.162 -9999.0 0.0 -0.387 66.0 66.0 establishment of cell polarity -0.095 0.209 -9999.0 0.0 -0.508 66.0 66.0 Nephrin/NEPH1/podocin/NCK1-2 -0.065 0.149 -9999.0 0.0 -0.429 38.0 38.0 Nephrin/NEPH1/beta Arrestin2 -0.044 0.156 -9999.0 0.0 -0.422 39.0 39.0 NPHS1 -0.087 0.229 -9999.0 0.0 -0.63 52.0 52.0 Nephrin/NEPH1/podocin -0.057 0.162 -9999.0 0.0 -0.449 39.0 39.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.038 -9999.0 0.0 -0.71 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.072 0.16 -9999.0 0.0 -0.456 39.0 39.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.071 0.16 -9999.0 0.0 -0.459 38.0 38.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.091 0.192 -9999.0 0.0 -0.415 74.0 74.0 cytoskeleton organization -0.039 0.169 -9999.0 0.0 -0.471 38.0 38.0 Nephrin/NEPH1 -0.07 0.156 -9999.0 0.0 -0.373 66.0 66.0 Nephrin/NEPH1/ZO-1 -0.077 0.171 -9999.0 0.0 -0.49 38.0 38.0