Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.064 0.186 0.486 34.0 -9999.0 0.0 34.0 KIRREL -0.031 0.158 -9999.0 0.0 -0.686 12.0 12.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.064 0.187 -9999.0 0.0 -0.487 34.0 34.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.056 0.135 -9999.0 0.0 -0.451 12.0 12.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.015 0.103 -9999.0 0.0 -0.347 12.0 12.0 FYN -0.039 0.133 -9999.0 0.0 -0.326 36.0 36.0 mol:Ca2+ -0.055 0.134 -9999.0 0.0 -0.446 12.0 12.0 mol:DAG -0.056 0.135 -9999.0 0.0 -0.449 12.0 12.0 NPHS2 -0.008 0.023 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.056 0.135 -9999.0 0.0 -0.449 12.0 12.0 regulation of endocytosis -0.03 0.126 -9999.0 0.0 -0.396 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.057 0.138 -9999.0 0.0 -0.365 34.0 34.0 establishment of cell polarity -0.064 0.186 -9999.0 0.0 -0.486 34.0 34.0 Nephrin/NEPH1/podocin/NCK1-2 -0.034 0.13 -9999.0 0.0 -0.41 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.03 0.128 -9999.0 0.0 -0.401 12.0 12.0 NPHS1 -0.063 0.193 -9999.0 0.0 -0.599 25.0 25.0 Nephrin/NEPH1/podocin -0.04 0.133 -9999.0 0.0 -0.328 36.0 36.0 TJP1 0.009 0.046 -9999.0 0.0 -0.677 1.0 1.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.056 0.135 -9999.0 0.0 -0.451 12.0 12.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.056 0.135 -9999.0 0.0 -0.358 34.0 34.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.058 0.157 -9999.0 0.0 -0.345 47.0 47.0 cytoskeleton organization -0.018 0.126 -9999.0 0.0 -0.417 12.0 12.0 Nephrin/NEPH1 -0.045 0.138 -9999.0 0.0 -0.353 34.0 34.0 Nephrin/NEPH1/ZO-1 -0.062 0.149 -9999.0 0.0 -0.482 13.0 13.0