Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.002 0.1 0.383 11.0 -9999.0 0.0 11.0 KIRREL -0.003 0.116 -9999.0 0.0 -0.493 11.0 11.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.002 0.1 -9999.0 0.0 -0.384 11.0 11.0 PLCG1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.014 0.081 -9999.0 0.0 -0.3 10.0 10.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.059 -9999.0 0.0 -0.263 8.0 8.0 FYN -0.001 0.084 0.275 1.0 -0.278 11.0 12.0 mol:Ca2+ 0.012 0.078 -9999.0 0.0 -0.299 9.0 9.0 mol:DAG 0.013 0.078 -9999.0 0.0 -0.301 9.0 9.0 NPHS2 -0.006 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.013 0.078 -9999.0 0.0 -0.301 9.0 9.0 regulation of endocytosis 0.017 0.077 -9999.0 0.0 -0.265 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol 0.001 0.074 -9999.0 0.0 -0.283 11.0 11.0 establishment of cell polarity -0.002 0.1 -9999.0 0.0 -0.383 11.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 0.021 0.077 -9999.0 0.0 -0.272 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 0.019 0.078 -9999.0 0.0 -0.268 11.0 11.0 NPHS1 -0.011 0.064 -9999.0 0.0 -0.209 3.0 3.0 Nephrin/NEPH1/podocin 0.004 0.074 -9999.0 0.0 -0.279 11.0 11.0 TJP1 0.026 0.037 -9999.0 0.0 -0.514 1.0 1.0 NCK1 0.024 0.011 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.013 0.079 -9999.0 0.0 -0.302 9.0 9.0 CD2AP 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.014 0.081 -9999.0 0.0 -0.3 10.0 10.0 GRB2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.006 0.088 0.287 2.0 -0.28 11.0 13.0 cytoskeleton organization -0.014 0.068 0.193 3.0 -0.297 9.0 12.0 Nephrin/NEPH1 0.004 0.071 -9999.0 0.0 -0.269 11.0 11.0 Nephrin/NEPH1/ZO-1 0.013 0.091 -9999.0 0.0 -0.326 11.0 11.0