Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.031	0.209	0.503	81.0	-0.444	16.0	97.0
IHH	-0.005	0.078	0.16	89.0	-9999.0	0.0	89.0
SHH Np/Cholesterol/GAS1	-0.044	0.037	0.144	1.0	-0.131	76.0	77.0
LRPAP1	0.028	0.007	-9999.0	0.0	0.0	37.0	37.0
dorsoventral neural tube patterning	0.044	0.037	0.13	76.0	-0.142	1.0	77.0
SMO/beta Arrestin2	0.025	0.132	0.297	84.0	-0.387	8.0	92.0
SMO	0.028	0.133	0.307	84.0	-0.396	8.0	92.0
AKT1	-0.025	0.147	0.273	13.0	-0.441	19.0	32.0
ARRB2	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0
BOC	0.025	0.01	-9999.0	0.0	0.0	80.0	80.0
ADRBK1	0.029	0.003	-9999.0	0.0	0.0	7.0	7.0
heart looping	0.028	0.133	0.306	84.0	-0.391	8.0	92.0
STIL	0.002	0.065	0.273	20.0	-9999.0	0.0	20.0
DHH N/PTCH2	0.042	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.006	0.134	0.315	79.0	-0.251	23.0	102.0
PIK3CA	0.021	0.014	-9999.0	0.0	0.0	171.0	171.0
DHH	0.029	0.003	-9999.0	0.0	0.0	5.0	5.0
PTHLH	0.032	0.194	0.496	71.0	-0.415	21.0	92.0
determination of left/right symmetry	0.028	0.133	0.306	84.0	-0.391	8.0	92.0
PIK3R1	0.021	0.013	-9999.0	0.0	0.0	161.0	161.0
skeletal system development	0.032	0.193	0.495	71.0	-0.412	21.0	92.0
IHH N/Hhip	0.049	0.042	0.181	3.0	-9999.0	0.0	3.0
DHH N/Hhip	0.042	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.028	0.133	0.306	84.0	-0.391	8.0	92.0
pancreas development	0.028	0.006	-9999.0	0.0	0.0	27.0	27.0
HHAT	0.029	0.005	-9999.0	0.0	0.0	18.0	18.0
PI3K	-0.0	0.067	-9999.0	0.0	-0.163	75.0	75.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.025	0.011	-9999.0	0.0	0.0	95.0	95.0
somite specification	0.028	0.133	0.306	84.0	-0.391	8.0	92.0
SHH Np/Cholesterol/PTCH1	-0.002	0.115	0.269	75.0	-0.232	20.0	95.0
SHH Np/Cholesterol/PTCH2	-0.032	0.016	0.144	1.0	-0.13	5.0	6.0
SHH Np/Cholesterol/Megalin	-0.025	0.018	-9999.0	0.0	-0.13	4.0	4.0
SHH	-0.03	0.014	0.195	1.0	-9999.0	0.0	1.0
catabolic process	0.023	0.158	0.38	84.0	-0.273	23.0	107.0
SMO/Vitamin D3	0.004	0.121	0.261	76.0	-0.362	8.0	84.0
SHH Np/Cholesterol/Hhip	-0.031	0.017	0.144	1.0	-0.13	5.0	6.0
LRP2	0.022	0.013	-9999.0	0.0	0.0	141.0	141.0
receptor-mediated endocytosis	0.025	0.125	0.279	75.0	-0.397	7.0	82.0
SHH Np/Cholesterol/BOC	-0.04	0.032	0.144	1.0	-0.13	55.0	56.0
SHH Np/Cholesterol/CDO	-0.032	0.018	0.144	1.0	-0.13	7.0	8.0
mesenchymal cell differentiation	0.031	0.016	0.129	5.0	-0.142	1.0	6.0
mol:Vitamin D3	0.005	0.119	0.238	102.0	-0.268	7.0	109.0
IHH N/PTCH2	0.05	0.041	0.181	4.0	-0.088	7.0	11.0
CDON	0.028	0.007	-9999.0	0.0	0.0	33.0	33.0
IHH N/PTCH1	-0.034	0.052	-9999.0	0.0	-0.274	23.0	23.0
Megalin/LRPAP1	0.03	0.023	-9999.0	0.0	-0.163	2.0	2.0
PTCH2	0.029	0.006	-9999.0	0.0	0.0	22.0	22.0
SHH Np/Cholesterol	-0.022	0.013	0.156	1.0	-0.119	5.0	6.0
PTCH1	0.023	0.159	0.38	84.0	-0.274	23.0	107.0
HHIP	0.028	0.006	-9999.0	0.0	0.0	27.0	27.0