Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.115 0.205 0.413 84.0 -9999.0 0.0 84.0 KIRREL -0.015 0.068 -9999.0 0.0 -0.527 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.116 0.205 -9999.0 0.0 -0.414 84.0 84.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.131 0.189 -9999.0 0.0 -0.442 68.0 68.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.08 0.16 -9999.0 0.0 -0.358 61.0 61.0 FYN -0.116 0.189 -9999.0 0.0 -0.417 71.0 71.0 mol:Ca2+ -0.13 0.187 -9999.0 0.0 -0.438 68.0 68.0 mol:DAG -0.13 0.188 -9999.0 0.0 -0.44 68.0 68.0 NPHS2 -0.097 0.227 -9999.0 0.0 -0.637 42.0 42.0 mol:IP3 -0.13 0.188 -9999.0 0.0 -0.44 68.0 68.0 regulation of endocytosis -0.103 0.178 -9999.0 0.0 -0.388 71.0 71.0 Nephrin/NEPH1/podocin/Cholesterol -0.134 0.192 -9999.0 0.0 -0.449 68.0 68.0 establishment of cell polarity -0.115 0.205 -9999.0 0.0 -0.413 84.0 84.0 Nephrin/NEPH1/podocin/NCK1-2 -0.103 0.184 -9999.0 0.0 -0.402 68.0 68.0 Nephrin/NEPH1/beta Arrestin2 -0.104 0.181 -9999.0 0.0 -0.393 71.0 71.0 NPHS1 -0.154 0.263 -9999.0 0.0 -0.553 83.0 83.0 Nephrin/NEPH1/podocin -0.117 0.19 -9999.0 0.0 -0.419 71.0 71.0 TJP1 0.01 0.024 -9999.0 0.0 -0.411 1.0 1.0 NCK1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.024 -9999.0 0.0 -0.411 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.131 0.189 -9999.0 0.0 -0.442 68.0 68.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.131 0.189 -9999.0 0.0 -0.442 68.0 68.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.115 0.192 -9999.0 0.0 -0.417 71.0 71.0 cytoskeleton organization -0.1 0.2 -9999.0 0.0 -0.446 63.0 63.0 Nephrin/NEPH1 -0.081 0.151 -9999.0 0.0 -0.403 42.0 42.0 Nephrin/NEPH1/ZO-1 -0.098 0.161 -9999.0 0.0 -0.447 41.0 41.0