Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.033 0.14 0.409 32.0 -9999.0 0.0 32.0 KIRREL 0.009 0.051 -9999.0 0.0 -0.586 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.033 0.14 -9999.0 0.0 -0.41 32.0 32.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.022 0.151 -9999.0 0.0 -0.326 53.0 53.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.041 0.126 -9999.0 0.0 -0.292 53.0 53.0 FYN -0.043 0.139 0.271 3.0 -0.304 55.0 58.0 mol:Ca2+ -0.021 0.148 -9999.0 0.0 -0.324 51.0 51.0 mol:DAG -0.021 0.149 -9999.0 0.0 -0.325 51.0 51.0 NPHS2 -0.044 0.168 -9999.0 0.0 -0.542 29.0 29.0 mol:IP3 -0.021 0.149 -9999.0 0.0 -0.325 51.0 51.0 regulation of endocytosis -0.02 0.135 -9999.0 0.0 -0.289 54.0 54.0 Nephrin/NEPH1/podocin/Cholesterol -0.032 0.144 -9999.0 0.0 -0.323 53.0 53.0 establishment of cell polarity -0.033 0.14 -9999.0 0.0 -0.409 32.0 32.0 Nephrin/NEPH1/podocin/NCK1-2 -0.007 0.147 -9999.0 0.0 -0.302 53.0 53.0 Nephrin/NEPH1/beta Arrestin2 -0.019 0.137 -9999.0 0.0 -0.292 54.0 54.0 NPHS1 -0.056 0.177 -9999.0 0.0 -0.544 33.0 33.0 Nephrin/NEPH1/podocin -0.029 0.139 -9999.0 0.0 -0.305 55.0 55.0 TJP1 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.02 0.15 -9999.0 0.0 -0.327 51.0 51.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.019 0.149 -9999.0 0.0 -0.323 52.0 52.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.047 0.136 0.281 3.0 -0.302 53.0 56.0 cytoskeleton organization -0.062 0.146 0.203 2.0 -0.357 52.0 54.0 Nephrin/NEPH1 -0.019 0.101 -9999.0 0.0 -0.296 31.0 31.0 Nephrin/NEPH1/ZO-1 -0.008 0.119 -9999.0 0.0 -0.338 30.0 30.0