Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.056 0.178 0.604 13.0 -9999.0 0.0 13.0 KIRREL -0.034 0.196 -9999.0 0.0 -0.887 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.056 0.178 -9999.0 0.0 -0.605 13.0 13.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.043 0.136 -9999.0 0.0 -0.542 7.0 7.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.0 0.102 -9999.0 0.0 -0.392 7.0 7.0 FYN -0.023 0.132 -9999.0 0.0 -0.512 7.0 7.0 mol:Ca2+ -0.042 0.134 -9999.0 0.0 -0.536 7.0 7.0 mol:DAG -0.042 0.135 -9999.0 0.0 -0.539 7.0 7.0 NPHS2 -0.004 0.021 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.042 0.135 -9999.0 0.0 -0.539 7.0 7.0 regulation of endocytosis -0.037 0.118 -9999.0 0.0 -0.478 7.0 7.0 Nephrin/NEPH1/podocin/Cholesterol -0.043 0.138 -9999.0 0.0 -0.467 13.0 13.0 establishment of cell polarity -0.056 0.178 -9999.0 0.0 -0.604 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 -0.039 0.123 -9999.0 0.0 -0.495 7.0 7.0 Nephrin/NEPH1/beta Arrestin2 -0.037 0.119 -9999.0 0.0 -0.485 7.0 7.0 NPHS1 -0.026 0.138 -9999.0 0.0 -0.67 6.0 6.0 Nephrin/NEPH1/podocin -0.04 0.127 -9999.0 0.0 -0.515 7.0 7.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.043 0.136 -9999.0 0.0 -0.542 7.0 7.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.043 0.136 -9999.0 0.0 -0.542 7.0 7.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.055 0.189 -9999.0 0.0 -0.568 12.0 12.0 cytoskeleton organization -0.001 0.131 -9999.0 0.0 -0.505 7.0 7.0 Nephrin/NEPH1 -0.042 0.134 -9999.0 0.0 -0.452 13.0 13.0 Nephrin/NEPH1/ZO-1 -0.046 0.146 -9999.0 0.0 -0.579 7.0 7.0