Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.026 0.113 0.304 1.0 -0.431 1.0 2.0 MAP3K8 0.024 0.051 -9999.0 0.0 -0.394 1.0 1.0 FOS 0.014 0.1 0.316 1.0 -0.38 2.0 3.0 PRKCA 0.031 0.019 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.04 0.032 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.031 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.025 0.052 -9999.0 0.0 -0.394 1.0 1.0 NRAS 0.018 0.07 -9999.0 0.0 -0.394 2.0 2.0 RAS family/GTP 0.033 0.085 -9999.0 0.0 -0.343 3.0 3.0 MAPK3 0.029 0.07 -9999.0 0.0 -0.488 1.0 1.0 MAP2K1 0.003 0.065 -9999.0 0.0 -0.346 1.0 1.0 ELK1 0.029 0.013 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.011 0.047 -9999.0 0.0 -0.342 1.0 1.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 2.0 2.0 MAPK1 -0.003 0.133 -9999.0 0.0 -0.382 7.0 7.0 RAF1 0.009 0.059 -9999.0 0.0 -0.32 2.0 2.0 KRAS 0.011 0.085 -9999.0 0.0 -0.394 3.0 3.0