Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.02 0.136 0.453 28.0 -9999.0 0.0 28.0 KIRREL -0.019 0.161 -9999.0 0.0 -0.584 28.0 28.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.02 0.136 -9999.0 0.0 -0.454 28.0 28.0 PLCG1 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.017 -9999.0 0.0 -0.259 1.0 1.0 WASL 0.028 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.001 0.108 -9999.0 0.0 -0.34 28.0 28.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.083 -9999.0 0.0 -0.29 26.0 26.0 FYN -0.009 0.103 -9999.0 0.0 -0.319 29.0 29.0 mol:Ca2+ -0.0 0.107 -9999.0 0.0 -0.337 28.0 28.0 mol:DAG 0.0 0.107 -9999.0 0.0 -0.338 28.0 28.0 NPHS2 -0.006 0.016 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.0 0.107 -9999.0 0.0 -0.338 28.0 28.0 regulation of endocytosis 0.007 0.1 -9999.0 0.0 -0.301 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol -0.013 0.102 -9999.0 0.0 -0.34 28.0 28.0 establishment of cell polarity -0.02 0.136 -9999.0 0.0 -0.453 28.0 28.0 Nephrin/NEPH1/podocin/NCK1-2 0.015 0.106 -9999.0 0.0 -0.311 28.0 28.0 Nephrin/NEPH1/beta Arrestin2 0.009 0.101 -9999.0 0.0 -0.304 29.0 29.0 NPHS1 -0.011 0.09 -9999.0 0.0 -0.278 33.0 33.0 Nephrin/NEPH1/podocin -0.008 0.099 -9999.0 0.0 -0.321 29.0 29.0 TJP1 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.001 0.108 -9999.0 0.0 -0.34 28.0 28.0 CD2AP 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.001 0.107 -9999.0 0.0 -0.34 27.0 27.0 GRB2 0.028 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.105 -9999.0 0.0 -0.321 29.0 29.0 cytoskeleton organization -0.012 0.098 -9999.0 0.0 -0.342 26.0 26.0 Nephrin/NEPH1 -0.01 0.099 -9999.0 0.0 -0.325 28.0 28.0 Nephrin/NEPH1/ZO-1 0.001 0.117 -9999.0 0.0 -0.366 28.0 28.0