Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.08 0.224 -9999.0 0.0 -0.547 45.0 45.0 MAP3K8 0.025 0.035 -9999.0 0.0 -0.417 2.0 2.0 FOS -0.077 0.209 -9999.0 0.0 -0.529 47.0 47.0 PRKCA 0.011 0.068 -9999.0 0.0 -0.306 14.0 14.0 PTPN7 -0.073 0.189 -9999.0 0.0 -0.394 84.0 84.0 HRAS 0.026 0.022 -9999.0 0.0 -0.259 2.0 2.0 PRKCB -0.035 0.142 -9999.0 0.0 -0.332 61.0 61.0 NRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.048 0.022 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.031 0.177 -9999.0 0.0 -0.513 38.0 38.0 MAP2K1 -0.003 0.11 -9999.0 0.0 -0.475 15.0 15.0 ELK1 0.022 0.018 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.005 0.104 -9999.0 0.0 -0.47 15.0 15.0 mol:GTP -0.001 0.003 -9999.0 0.0 -0.005 56.0 56.0 MAPK1 -0.111 0.234 -9999.0 0.0 -0.438 103.0 103.0 RAF1 -0.006 0.106 -9999.0 0.0 -0.478 15.0 15.0 KRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0