Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.046	0.236	0.585	2.0	-0.556	73.0	75.0
IHH	0.021	0.075	-9999.0	0.0	-0.198	1.0	1.0
SHH Np/Cholesterol/GAS1	-0.067	0.147	-9999.0	0.0	-0.314	124.0	124.0
LRPAP1	0.033	0.007	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.067	0.146	0.312	124.0	-9999.0	0.0	124.0
SMO/beta Arrestin2	-0.003	0.187	0.409	2.0	-0.483	29.0	31.0
SMO	-0.017	0.185	0.441	2.0	-0.5	30.0	32.0
AKT1	-0.02	0.19	0.305	1.0	-0.593	36.0	37.0
ARRB2	0.031	0.01	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.09	0.236	-9999.0	0.0	-0.543	108.0	108.0
ADRBK1	0.031	0.01	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
STIL	0.041	0.15	0.34	31.0	-0.341	7.0	38.0
DHH N/PTCH2	0.049	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.005	0.163	0.376	2.0	-0.325	81.0	83.0
PIK3CA	0.032	0.008	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.034	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PTHLH	-0.113	0.393	0.663	2.0	-0.899	94.0	96.0
determination of left/right symmetry	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
PIK3R1	-0.019	0.164	-9999.0	0.0	-0.543	45.0	45.0
skeletal system development	-0.11	0.388	0.662	2.0	-0.887	94.0	96.0
IHH N/Hhip	0.038	0.053	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/Hhip	0.05	0.012	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
pancreas development	0.034	0.012	-9999.0	0.0	-9999.0	0.0	0.0
HHAT	0.023	0.06	-9999.0	0.0	-0.543	5.0	5.0
PI3K	0.006	0.125	-9999.0	0.0	-0.4	42.0	42.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.143	0.266	-9999.0	0.0	-0.543	155.0	155.0
somite specification	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
SHH Np/Cholesterol/PTCH1	-0.01	0.122	-9999.0	0.0	-0.337	13.0	13.0
SHH Np/Cholesterol/PTCH2	0.024	0.037	-9999.0	0.0	-0.312	5.0	5.0
SHH Np/Cholesterol/Megalin	-0.057	0.145	-9999.0	0.0	-0.32	110.0	110.0
SHH	0.01	0.043	-9999.0	0.0	-0.4	5.0	5.0
catabolic process	-0.01	0.176	0.462	2.0	-0.358	86.0	88.0
SMO/Vitamin D3	0.009	0.172	0.405	16.0	-0.452	13.0	29.0
SHH Np/Cholesterol/Hhip	0.024	0.038	-9999.0	0.0	-0.312	5.0	5.0
LRP2	-0.121	0.256	-9999.0	0.0	-0.543	136.0	136.0
receptor-mediated endocytosis	-0.063	0.196	0.347	9.0	-0.509	38.0	47.0
SHH Np/Cholesterol/BOC	-0.037	0.129	-9999.0	0.0	-0.312	84.0	84.0
SHH Np/Cholesterol/CDO	0.018	0.051	-9999.0	0.0	-0.346	8.0	8.0
mesenchymal cell differentiation	-0.024	0.038	0.31	5.0	-9999.0	0.0	5.0
mol:Vitamin D3	0.027	0.159	0.41	17.0	-0.369	9.0	26.0
IHH N/PTCH2	0.037	0.052	-9999.0	0.0	-9999.0	0.0	0.0
CDON	0.026	0.052	-9999.0	0.0	-0.543	4.0	4.0
IHH N/PTCH1	-0.002	0.18	0.463	2.0	-0.36	86.0	88.0
Megalin/LRPAP1	-0.073	0.199	-9999.0	0.0	-0.394	139.0	139.0
PTCH2	0.034	0.005	-9999.0	0.0	-9999.0	0.0	0.0
SHH Np/Cholesterol	0.014	0.034	-9999.0	0.0	-0.31	5.0	5.0
PTCH1	-0.01	0.176	0.463	2.0	-0.359	86.0	88.0
HHIP	0.034	0.012	-9999.0	0.0	-9999.0	0.0	0.0