Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.075 0.179 0.675 61.0 -9999.0 0.0 61.0 KIRREL -0.061 0.219 -9999.0 0.0 -0.845 61.0 61.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.075 0.179 -9999.0 0.0 -0.677 61.0 61.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.054 0.136 -9999.0 0.0 -0.521 61.0 61.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.03 0.098 -9999.0 0.0 -0.38 61.0 61.0 FYN -0.05 0.131 -9999.0 0.0 -0.498 61.0 61.0 mol:Ca2+ -0.054 0.135 -9999.0 0.0 -0.516 61.0 61.0 mol:DAG -0.054 0.136 -9999.0 0.0 -0.519 61.0 61.0 NPHS2 -0.008 0.03 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.054 0.136 -9999.0 0.0 -0.519 61.0 61.0 regulation of endocytosis -0.022 0.129 -9999.0 0.0 -0.465 61.0 61.0 Nephrin/NEPH1/podocin/Cholesterol -0.056 0.139 -9999.0 0.0 -0.53 61.0 61.0 establishment of cell polarity -0.075 0.179 -9999.0 0.0 -0.675 61.0 61.0 Nephrin/NEPH1/podocin/NCK1-2 -0.021 0.132 -9999.0 0.0 -0.476 61.0 61.0 Nephrin/NEPH1/beta Arrestin2 -0.022 0.131 -9999.0 0.0 -0.471 61.0 61.0 NPHS1 -0.049 0.103 -9999.0 0.0 -0.354 10.0 10.0 Nephrin/NEPH1/podocin -0.044 0.134 -9999.0 0.0 -0.501 61.0 61.0 TJP1 -0.001 0.029 -9999.0 0.0 -0.838 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.054 0.136 -9999.0 0.0 -0.521 61.0 61.0 CD2AP -0.0 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.054 0.137 -9999.0 0.0 -0.521 61.0 61.0 GRB2 -0.0 0.01 -9999.0 0.0 -0.278 1.0 1.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.056 0.144 -9999.0 0.0 -0.516 67.0 67.0 cytoskeleton organization -0.039 0.124 -9999.0 0.0 -0.482 61.0 61.0 Nephrin/NEPH1 -0.054 0.135 -9999.0 0.0 -0.513 61.0 61.0 Nephrin/NEPH1/ZO-1 -0.059 0.15 -9999.0 0.0 -0.567 61.0 61.0