Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.015 0.096 0.319 17.0 -9999.0 0.0 17.0 KIRREL -0.01 0.095 -9999.0 0.0 -0.463 8.0 8.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.015 0.096 -9999.0 0.0 -0.319 17.0 17.0 PLCG1 0.005 0.057 -9999.0 0.0 -0.447 3.0 3.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.028 0.122 -9999.0 0.0 -0.317 23.0 23.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.004 0.073 -9999.0 0.0 -0.347 3.0 3.0 FYN -0.011 0.08 -9999.0 0.0 -0.284 8.0 8.0 mol:Ca2+ -0.008 0.093 -9999.0 0.0 -0.32 10.0 10.0 mol:DAG -0.008 0.093 -9999.0 0.0 -0.321 10.0 10.0 NPHS2 -0.011 0.073 -9999.0 0.0 -0.446 5.0 5.0 mol:IP3 -0.008 0.093 -9999.0 0.0 -0.321 10.0 10.0 regulation of endocytosis -0.001 0.077 -9999.0 0.0 -0.348 3.0 3.0 Nephrin/NEPH1/podocin/Cholesterol -0.012 0.082 -9999.0 0.0 -0.242 20.0 20.0 establishment of cell polarity -0.015 0.096 -9999.0 0.0 -0.319 17.0 17.0 Nephrin/NEPH1/podocin/NCK1-2 0.001 0.085 -9999.0 0.0 -0.362 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.001 0.078 -9999.0 0.0 -0.352 3.0 3.0 NPHS1 -0.014 0.096 -9999.0 0.0 -0.44 9.0 9.0 Nephrin/NEPH1/podocin -0.01 0.081 -9999.0 0.0 -0.285 8.0 8.0 TJP1 0.01 0.035 -9999.0 0.0 -0.47 1.0 1.0 NCK1 0.008 0.049 -9999.0 0.0 -0.47 2.0 2.0 NCK2 0.01 0.035 -9999.0 0.0 -0.47 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.007 0.094 -9999.0 0.0 -0.322 10.0 10.0 CD2AP -0.03 0.137 -9999.0 0.0 -0.47 17.0 17.0 Nephrin/NEPH1/podocin/GRB2 -0.003 0.082 -9999.0 0.0 -0.303 6.0 6.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.02 0.096 -9999.0 0.0 -0.27 18.0 18.0 cytoskeleton organization 0.006 0.077 -9999.0 0.0 -0.361 3.0 3.0 Nephrin/NEPH1 -0.008 0.066 -9999.0 0.0 -0.219 17.0 17.0 Nephrin/NEPH1/ZO-1 -0.003 0.083 -9999.0 0.0 -0.259 17.0 17.0