Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.024 0.106 0.317 30.0 -9999.0 0.0 30.0 KIRREL -0.011 0.095 -9999.0 0.0 -0.464 11.0 11.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.024 0.106 -9999.0 0.0 -0.318 30.0 30.0 PLCG1 0.009 0.041 -9999.0 0.0 -0.459 2.0 2.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.035 0.127 -9999.0 0.0 -0.337 29.0 29.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.0 0.072 -9999.0 0.0 -0.328 4.0 4.0 FYN -0.017 0.085 -9999.0 0.0 -0.292 10.0 10.0 mol:Ca2+ -0.013 0.096 -9999.0 0.0 -0.411 6.0 6.0 mol:DAG -0.013 0.096 -9999.0 0.0 -0.413 6.0 6.0 NPHS2 -0.014 0.079 -9999.0 0.0 -0.452 8.0 8.0 mol:IP3 -0.013 0.096 -9999.0 0.0 -0.413 6.0 6.0 regulation of endocytosis -0.007 0.081 -9999.0 0.0 -0.353 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.089 -9999.0 0.0 -0.238 35.0 35.0 establishment of cell polarity -0.024 0.106 -9999.0 0.0 -0.317 30.0 30.0 Nephrin/NEPH1/podocin/NCK1-2 -0.005 0.089 -9999.0 0.0 -0.401 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.006 0.082 -9999.0 0.0 -0.357 4.0 4.0 NPHS1 -0.025 0.117 -9999.0 0.0 -0.444 19.0 19.0 Nephrin/NEPH1/podocin -0.016 0.086 -9999.0 0.0 -0.293 10.0 10.0 TJP1 0.01 0.03 -9999.0 0.0 -0.476 1.0 1.0 NCK1 0.008 0.042 -9999.0 0.0 -0.476 2.0 2.0 NCK2 0.01 0.03 -9999.0 0.0 -0.476 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.013 0.097 -9999.0 0.0 -0.415 6.0 6.0 CD2AP -0.029 0.135 -9999.0 0.0 -0.476 22.0 22.0 Nephrin/NEPH1/podocin/GRB2 -0.011 0.09 -9999.0 0.0 -0.299 10.0 10.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.023 0.099 -9999.0 0.0 -0.309 15.0 15.0 cytoskeleton organization 0.001 0.079 -9999.0 0.0 -0.356 4.0 4.0 Nephrin/NEPH1 -0.014 0.074 -9999.0 0.0 -0.218 30.0 30.0 Nephrin/NEPH1/ZO-1 -0.01 0.089 -9999.0 0.0 -0.254 27.0 27.0