Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.029 0.127 0.412 15.0 -9999.0 0.0 15.0 KIRREL -0.043 0.171 -9999.0 0.0 -0.564 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.029 0.127 -9999.0 0.0 -0.413 15.0 15.0 PLCG1 0.009 0.047 -9999.0 0.0 -0.573 1.0 1.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.011 0.096 -9999.0 0.0 -0.307 13.0 13.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.084 -9999.0 0.0 -0.266 10.0 10.0 FYN -0.014 0.09 -9999.0 0.0 -0.293 13.0 13.0 mol:Ca2+ -0.032 0.099 -9999.0 0.0 -0.329 13.0 13.0 mol:DAG -0.022 0.103 -9999.0 0.0 -0.33 13.0 13.0 NPHS2 -0.005 0.042 -9999.0 0.0 -0.481 1.0 1.0 mol:IP3 -0.022 0.103 -9999.0 0.0 -0.33 13.0 13.0 regulation of endocytosis -0.005 0.085 -9999.0 0.0 -0.27 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.096 -9999.0 0.0 -0.3 16.0 16.0 establishment of cell polarity -0.029 0.127 -9999.0 0.0 -0.412 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 -0.003 0.091 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.004 0.087 -9999.0 0.0 -0.273 13.0 13.0 NPHS1 0.001 0.017 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.014 0.091 -9999.0 0.0 -0.295 13.0 13.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.04 -9999.0 0.0 -0.487 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.013 0.106 -9999.0 0.0 -0.332 13.0 13.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.011 0.096 -9999.0 0.0 -0.307 13.0 13.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.036 0.126 -9999.0 0.0 -0.316 22.0 22.0 cytoskeleton organization 0.001 0.096 -9999.0 0.0 -0.299 10.0 10.0 Nephrin/NEPH1 -0.019 0.09 -9999.0 0.0 -0.292 15.0 15.0 Nephrin/NEPH1/ZO-1 -0.013 0.102 -9999.0 0.0 -0.333 13.0 13.0