Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.046 0.162 0.623 22.0 -9999.0 0.0 22.0 KIRREL 0.006 0.042 -9999.0 0.0 -0.644 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.047 0.163 -9999.0 0.0 -0.625 22.0 22.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.159 -9999.0 0.0 -0.545 25.0 25.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.002 0.105 -9999.0 0.0 -0.559 5.0 5.0 FYN -0.025 0.152 -9999.0 0.0 -0.492 26.0 26.0 mol:Ca2+ -0.046 0.157 -9999.0 0.0 -0.538 25.0 25.0 mol:DAG -0.046 0.158 -9999.0 0.0 -0.542 25.0 25.0 NPHS2 -0.025 0.143 -9999.0 0.0 -0.837 9.0 9.0 mol:IP3 -0.046 0.158 -9999.0 0.0 -0.542 25.0 25.0 regulation of endocytosis -0.04 0.137 -9999.0 0.0 -0.483 20.0 20.0 Nephrin/NEPH1/podocin/Cholesterol -0.047 0.162 -9999.0 0.0 -0.546 26.0 26.0 establishment of cell polarity -0.046 0.162 -9999.0 0.0 -0.623 22.0 22.0 Nephrin/NEPH1/podocin/NCK1-2 -0.042 0.147 -9999.0 0.0 -0.846 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.041 0.139 -9999.0 0.0 -0.731 6.0 6.0 NPHS1 -0.05 0.209 -9999.0 0.0 -0.814 21.0 21.0 Nephrin/NEPH1/podocin -0.044 0.148 -9999.0 0.0 -0.496 26.0 26.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.046 0.159 -9999.0 0.0 -0.545 25.0 25.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.046 0.159 -9999.0 0.0 -0.545 25.0 25.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.063 0.206 -9999.0 0.0 -0.514 49.0 49.0 cytoskeleton organization 0.0 0.139 -9999.0 0.0 -0.75 5.0 5.0 Nephrin/NEPH1 -0.035 0.122 -9999.0 0.0 -0.468 22.0 22.0 Nephrin/NEPH1/ZO-1 -0.038 0.133 -9999.0 0.0 -0.516 21.0 21.0