Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.447 0.207 0.528 55.0 -9999.0 0.0 55.0 KIRREL -0.095 0.138 -9999.0 0.0 -0.695 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.448 0.208 -9999.0 0.0 -0.529 55.0 55.0 PLCG1 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.024 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.446 0.252 -9999.0 0.0 -0.514 57.0 57.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.393 0.221 -9999.0 0.0 -0.459 55.0 55.0 FYN -0.426 0.227 -9999.0 0.0 -0.484 57.0 57.0 mol:Ca2+ -0.443 0.247 -9999.0 0.0 -0.51 57.0 57.0 mol:DAG -0.445 0.25 -9999.0 0.0 -0.513 57.0 57.0 NPHS2 -0.302 0.309 -9999.0 0.0 -0.692 25.0 25.0 mol:IP3 -0.445 0.25 -9999.0 0.0 -0.513 57.0 57.0 regulation of endocytosis -0.397 0.229 -9999.0 0.0 -0.458 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.446 0.248 -9999.0 0.0 -0.512 57.0 57.0 establishment of cell polarity -0.447 0.207 -9999.0 0.0 -0.528 55.0 55.0 Nephrin/NEPH1/podocin/NCK1-2 -0.417 0.242 -9999.0 0.0 -0.483 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.403 0.234 -9999.0 0.0 -0.465 57.0 57.0 NPHS1 -0.555 0.241 -9999.0 0.0 -0.663 54.0 54.0 Nephrin/NEPH1/podocin -0.424 0.238 -9999.0 0.0 -0.488 57.0 57.0 TJP1 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.023 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.447 0.252 -9999.0 0.0 -0.516 57.0 57.0 CD2AP 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.446 0.252 -9999.0 0.0 -0.514 57.0 57.0 GRB2 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.414 0.221 -9999.0 0.0 -0.475 56.0 56.0 cytoskeleton organization -0.489 0.255 -9999.0 0.0 -0.562 56.0 56.0 Nephrin/NEPH1 -0.327 0.158 -9999.0 0.0 -0.387 55.0 55.0 Nephrin/NEPH1/ZO-1 -0.361 0.175 -9999.0 0.0 -0.43 55.0 55.0