Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.394 0.231 0.526 350.0 -9999.0 0.0 350.0 KIRREL -0.053 0.057 -9999.0 0.0 -0.508 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.395 0.231 -9999.0 0.0 -0.527 350.0 350.0 PLCG1 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.034 -9999.0 0.0 -0.706 1.0 1.0 WASL 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.416 0.281 -9999.0 0.0 -0.542 367.0 367.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.338 0.232 -9999.0 0.0 -0.565 204.0 204.0 FYN -0.399 0.255 0.264 1.0 -0.51 369.0 370.0 mol:Ca2+ -0.408 0.277 -9999.0 0.0 -0.536 362.0 362.0 mol:DAG -0.41 0.279 -9999.0 0.0 -0.539 362.0 362.0 NPHS2 -0.341 0.328 -9999.0 0.0 -0.692 219.0 219.0 mol:IP3 -0.41 0.279 -9999.0 0.0 -0.539 362.0 362.0 regulation of endocytosis -0.372 0.25 -9999.0 0.0 -0.625 195.0 195.0 Nephrin/NEPH1/podocin/Cholesterol -0.421 0.277 -9999.0 0.0 -0.541 373.0 373.0 establishment of cell polarity -0.394 0.231 -9999.0 0.0 -0.526 350.0 350.0 Nephrin/NEPH1/podocin/NCK1-2 -0.379 0.269 -9999.0 0.0 -0.649 195.0 195.0 Nephrin/NEPH1/beta Arrestin2 -0.377 0.255 -9999.0 0.0 -0.636 195.0 195.0 NPHS1 -0.516 0.285 -9999.0 0.0 -0.67 365.0 365.0 Nephrin/NEPH1/podocin -0.397 0.264 -9999.0 0.0 -0.511 373.0 373.0 TJP1 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.412 0.281 -9999.0 0.0 -0.542 362.0 362.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.414 0.281 -9999.0 0.0 -0.541 366.0 366.0 GRB2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.391 0.255 0.276 1.0 -0.503 366.0 367.0 cytoskeleton organization -0.431 0.285 -9999.0 0.0 -0.583 332.0 332.0 Nephrin/NEPH1 -0.286 0.172 -9999.0 0.0 -0.385 350.0 350.0 Nephrin/NEPH1/ZO-1 -0.315 0.198 -9999.0 0.0 -0.429 349.0 349.0