Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.046 0.109 0.378 2.0 -0.527 8.0 10.0 MAP3K8 0.027 0.04 -9999.0 0.0 -0.588 2.0 2.0 FOS 0.031 0.099 0.382 3.0 -0.491 7.0 10.0 PRKCA 0.029 0.009 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.01 0.151 -9999.0 0.0 -0.587 30.0 30.0 HRAS 0.03 0.003 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.022 0.067 -9999.0 0.0 -0.617 5.0 5.0 NRAS 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.055 0.016 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.019 0.085 -9999.0 0.0 -0.529 6.0 6.0 MAP2K1 0.029 0.054 -9999.0 0.0 -0.431 3.0 3.0 ELK1 0.029 0.007 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.029 0.041 -9999.0 0.0 -0.449 2.0 2.0 mol:GTP 0.0 0.002 -9999.0 0.0 -0.01 10.0 10.0 MAPK1 0.018 0.089 -9999.0 0.0 -0.415 12.0 12.0 RAF1 0.022 0.042 -9999.0 0.0 -0.449 2.0 2.0 KRAS 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0