Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.389 0.263 0.547 53.0 -9999.0 0.0 53.0 KIRREL -0.082 0.12 -9999.0 0.0 -0.742 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.39 0.263 -9999.0 0.0 -0.549 53.0 53.0 PLCG1 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.438 0.311 -9999.0 0.0 -0.585 58.0 58.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.37 0.271 -9999.0 0.0 -0.52 52.0 52.0 FYN -0.43 0.271 -9999.0 0.0 -0.553 58.0 58.0 mol:Ca2+ -0.431 0.305 -9999.0 0.0 -0.586 56.0 56.0 mol:DAG -0.434 0.308 -9999.0 0.0 -0.589 56.0 56.0 NPHS2 -0.392 0.33 -9999.0 0.0 -0.703 40.0 40.0 mol:IP3 -0.434 0.308 -9999.0 0.0 -0.589 56.0 56.0 regulation of endocytosis -0.393 0.275 -9999.0 0.0 -0.526 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.443 0.304 -9999.0 0.0 -0.584 58.0 58.0 establishment of cell polarity -0.389 0.263 -9999.0 0.0 -0.547 53.0 53.0 Nephrin/NEPH1/podocin/NCK1-2 -0.413 0.299 -9999.0 0.0 -0.558 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.399 0.281 -9999.0 0.0 -0.534 57.0 57.0 NPHS1 -0.493 0.299 -9999.0 0.0 -0.681 54.0 54.0 Nephrin/NEPH1/podocin -0.423 0.29 -9999.0 0.0 -0.557 58.0 58.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.437 0.311 -9999.0 0.0 -0.593 56.0 56.0 CD2AP 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.434 0.309 -9999.0 0.0 -0.59 56.0 56.0 GRB2 0.024 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.479 0.288 -9999.0 0.0 -0.591 61.0 61.0 cytoskeleton organization -0.459 0.321 -9999.0 0.0 -0.648 51.0 51.0 Nephrin/NEPH1 -0.285 0.201 -9999.0 0.0 -0.414 51.0 51.0 Nephrin/NEPH1/ZO-1 -0.32 0.228 -9999.0 0.0 -0.472 50.0 50.0