Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.005	0.077	-9999.0	0.0	-0.289	5.0	5.0
epithelial cell differentiation	0.022	0.107	-9999.0	0.0	-0.374	5.0	5.0
CYFIP2	0.026	0.006	-9999.0	0.0	-9999.0	0.0	0.0
ENAH	-0.022	0.115	0.478	2.0	-9999.0	0.0	2.0
EGFR	0.023	0.01	-9999.0	0.0	-9999.0	0.0	0.0
EPHA2	0.025	0.007	-9999.0	0.0	-9999.0	0.0	0.0
MYO6	-0.023	0.116	0.342	2.0	-0.364	5.0	7.0
CTNNB1	0.027	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ABI1/Sra1/Nap1	0.049	0.019	-9999.0	0.0	-9999.0	0.0	0.0
AQP5	-0.097	0.203	-9999.0	0.0	-0.578	10.0	10.0
CTNND1	0.027	0.003	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	-0.021	0.116	0.34	2.0	-0.359	5.0	7.0
regulation of calcium-dependent cell-cell adhesion	-0.041	0.142	0.34	2.0	-0.405	7.0	9.0
EGF	-0.513	0.262	-9999.0	0.0	-0.634	62.0	62.0
NCKAP1	0.027	0.004	-9999.0	0.0	-9999.0	0.0	0.0
AQP3	-0.141	0.233	-9999.0	0.0	-0.555	16.0	16.0
cortical microtubule organization	0.022	0.107	-9999.0	0.0	-0.374	5.0	5.0
GO:0000145	-0.021	0.111	0.327	2.0	-0.342	5.0	7.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.026	0.11	-9999.0	0.0	-0.378	5.0	5.0
MLLT4	0.026	0.007	-9999.0	0.0	-9999.0	0.0	0.0
ARF6/GDP	-0.048	0.072	-9999.0	0.0	-0.337	4.0	4.0
ARF6	0.026	0.006	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.058	0.028	-9999.0	0.0	-9999.0	0.0	0.0
mol:Ca2+	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.025	0.091	-9999.0	0.0	-0.335	5.0	5.0
PVRL2	0.027	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ZYX	-0.034	0.095	-9999.0	0.0	-0.364	5.0	5.0
ARF6/GTP	0.06	0.034	-9999.0	0.0	-9999.0	0.0	0.0
CDH1	-0.019	0.167	-9999.0	0.0	-0.649	5.0	5.0
EGFR/EGFR/EGF/EGF	-0.259	0.177	-9999.0	0.0	-0.382	46.0	46.0
RhoA/GDP	0.024	0.104	-9999.0	0.0	-0.36	5.0	5.0
actin cytoskeleton organization	-0.024	0.111	0.323	2.0	-0.355	5.0	7.0
IGF-1R heterotetramer	0.026	0.005	-9999.0	0.0	-9999.0	0.0	0.0
GIT1	0.026	0.007	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	0.027	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IGF1	0.018	0.077	-9999.0	0.0	-0.649	1.0	1.0
DIAPH1	0.023	0.12	-9999.0	0.0	-0.563	1.0	1.0
Wnt receptor signaling pathway	-0.022	0.107	0.374	5.0	-9999.0	0.0	5.0
RHOA	0.027	0.005	-9999.0	0.0	-9999.0	0.0	0.0
RhoA/GTP	-0.049	0.073	-9999.0	0.0	-0.34	4.0	4.0
CTNNA1	0.026	0.006	-9999.0	0.0	-9999.0	0.0	0.0
VCL	-0.025	0.113	0.326	2.0	-0.363	5.0	7.0
EFNA1	0.026	0.007	-9999.0	0.0	-9999.0	0.0	0.0
LPP	-0.029	0.105	0.332	1.0	-0.352	5.0	6.0
Ephrin A1/EPHA2	0.017	0.102	-9999.0	0.0	-0.358	5.0	5.0
SEC6/SEC8	-0.046	0.081	-9999.0	0.0	-0.348	5.0	5.0
MGAT3	-0.042	0.144	0.342	2.0	-0.412	7.0	9.0
HGF/MET	0.003	0.112	-9999.0	0.0	-0.359	6.0	6.0
HGF	0.005	0.108	-9999.0	0.0	-0.649	2.0	2.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.005	0.078	-9999.0	0.0	-0.291	5.0	5.0
actin cable formation	0.016	0.158	0.518	5.0	-9999.0	0.0	5.0
KIAA1543	-0.021	0.112	0.329	2.0	-0.348	5.0	7.0
KIFC3	-0.039	0.092	-9999.0	0.0	-0.364	5.0	5.0
NCK1	0.027	0.005	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.025	0.007	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	-0.02	0.118	0.342	2.0	-0.364	5.0	7.0
NCK1/GIT1	0.037	0.012	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	0.022	0.107	-9999.0	0.0	-0.374	5.0	5.0
EXOC4	0.023	0.011	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.041	0.089	-9999.0	0.0	-0.364	5.0	5.0
PIP5K1C	-0.022	0.118	0.342	2.0	-0.364	5.0	7.0
LIMA1	0.027	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ABI1	0.026	0.006	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	-0.008	0.148	0.43	5.0	-9999.0	0.0	5.0
adherens junction assembly	-0.002	0.129	0.395	3.0	-9999.0	0.0	3.0
IGF-1R heterotetramer/IGF1	0.011	0.111	-9999.0	0.0	-0.359	6.0	6.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.038	0.011	-9999.0	0.0	-9999.0	0.0	0.0
MET	0.023	0.015	-9999.0	0.0	-9999.0	0.0	0.0
PLEKHA7	-0.021	0.118	0.342	2.0	-0.364	5.0	7.0
mol:GTP	0.056	0.027	-9999.0	0.0	-9999.0	0.0	0.0
establishment of epithelial cell apical/basal polarity	-0.024	0.11	0.314	1.0	-9999.0	0.0	1.0
cortical actin cytoskeleton stabilization	-0.005	0.077	-9999.0	0.0	-0.289	5.0	5.0
regulation of cell-cell adhesion	-0.024	0.111	0.323	2.0	-0.355	5.0	7.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.005	0.078	-9999.0	0.0	-0.291	5.0	5.0