Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.044 0.203 -9999.0 0.0 -0.577 2.0 2.0 MAP3K8 0.008 0.092 -9999.0 0.0 -0.434 1.0 1.0 FOS -0.023 0.142 -9999.0 0.0 -0.447 2.0 2.0 PRKCA 0.025 0.022 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.016 0.038 -9999.0 0.0 -0.128 1.0 1.0 HRAS 0.031 0.013 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.004 0.007 -9999.0 0.0 -0.016 7.0 7.0 NRAS 0.028 0.015 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.039 0.032 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.014 0.097 -9999.0 0.0 -0.415 1.0 1.0 MAP2K1 0.017 0.062 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.023 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.006 0.019 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 8.0 8.0 MAPK1 -0.03 0.159 -9999.0 0.0 -0.503 2.0 2.0 RAF1 0.006 0.022 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.031 0.013 -9999.0 0.0 -9999.0 0.0 0.0