Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.031 0.101 0.363 30.0 -9999.0 0.0 30.0 KIRREL -0.007 0.086 -9999.0 0.0 -0.507 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.031 0.101 -9999.0 0.0 -0.364 30.0 30.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.022 0.071 -9999.0 0.0 -9999.0 0.0 0.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.009 0.053 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.005 0.068 -9999.0 0.0 -0.247 10.0 10.0 mol:Ca2+ -0.022 0.071 -9999.0 0.0 -9999.0 0.0 0.0 mol:DAG -0.022 0.071 -9999.0 0.0 -9999.0 0.0 0.0 NPHS2 -0.001 0.014 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.022 0.071 -9999.0 0.0 -9999.0 0.0 0.0 regulation of endocytosis -0.018 0.058 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.022 0.073 -9999.0 0.0 -0.262 30.0 30.0 establishment of cell polarity -0.031 0.101 -9999.0 0.0 -0.363 30.0 30.0 Nephrin/NEPH1/podocin/NCK1-2 -0.019 0.063 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.018 0.059 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.023 0.121 -9999.0 0.0 -0.516 20.0 20.0 Nephrin/NEPH1/podocin -0.02 0.064 -9999.0 0.0 -0.248 10.0 10.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.022 0.071 -9999.0 0.0 -9999.0 0.0 0.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.022 0.071 -9999.0 0.0 -0.255 28.0 28.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.023 0.101 -9999.0 0.0 -0.284 26.0 26.0 cytoskeleton organization 0.013 0.062 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.022 0.071 -9999.0 0.0 -0.253 30.0 30.0 Nephrin/NEPH1/ZO-1 -0.024 0.078 -9999.0 0.0 -0.281 30.0 30.0