Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.092	0.184	0.265	23.0	-0.505	30.0	53.0
IHH	-0.152	0.211	0.338	4.0	-0.381	157.0	161.0
SHH Np/Cholesterol/GAS1	-0.038	0.06	0.115	1.0	-0.187	47.0	48.0
LRPAP1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.037	0.06	0.186	47.0	-0.114	1.0	48.0
SMO/beta Arrestin2	-0.146	0.181	0.319	1.0	-0.329	130.0	131.0
SMO	-0.147	0.186	0.343	1.0	-0.338	139.0	140.0
AKT1	-0.08	0.146	0.266	1.0	-0.504	23.0	24.0
ARRB2	0.019	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ADRBK1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.146	0.183	0.342	1.0	-0.333	140.0	141.0
STIL	-0.083	0.145	0.265	9.0	-0.31	48.0	57.0
DHH N/PTCH2	0.013	0.066	-9999.0	0.0	-0.236	23.0	23.0
DHH N/PTCH1	-0.105	0.152	-9999.0	0.0	-0.357	41.0	41.0
PIK3CA	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.001	0.086	-9999.0	0.0	-0.335	22.0	22.0
PTHLH	-0.123	0.223	0.38	5.0	-0.57	28.0	33.0
determination of left/right symmetry	-0.146	0.183	0.342	1.0	-0.333	140.0	141.0
PIK3R1	0.02	0.005	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.122	0.222	0.379	5.0	-0.566	28.0	33.0
IHH N/Hhip	-0.231	0.18	0.212	3.0	-0.322	264.0	267.0
DHH N/Hhip	-0.126	0.145	-9999.0	0.0	-0.252	194.0	194.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.146	0.183	0.342	1.0	-0.333	140.0	141.0
pancreas development	-0.173	0.176	-9999.0	0.0	-0.334	192.0	192.0
HHAT	0.018	0.027	-9999.0	0.0	-0.335	2.0	2.0
PI3K	0.029	0.009	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.01	0.059	-9999.0	0.0	-0.335	10.0	10.0
somite specification	-0.146	0.183	0.342	1.0	-0.333	140.0	141.0
SHH Np/Cholesterol/PTCH1	-0.099	0.138	0.176	1.0	-0.325	52.0	53.0
SHH Np/Cholesterol/PTCH2	-0.035	0.055	0.115	1.0	-0.181	42.0	43.0
SHH Np/Cholesterol/Megalin	-0.07	0.091	0.115	1.0	-0.202	105.0	106.0
SHH	-0.041	0.073	0.156	1.0	-0.237	42.0	43.0
catabolic process	-0.106	0.16	0.232	2.0	-0.254	164.0	166.0
SMO/Vitamin D3	-0.122	0.173	0.37	2.0	-0.396	48.0	50.0
SHH Np/Cholesterol/Hhip	-0.11	0.104	0.115	1.0	-0.204	179.0	180.0
LRP2	-0.072	0.158	0.331	1.0	-0.335	93.0	94.0
receptor-mediated endocytosis	-0.166	0.184	0.303	2.0	-0.406	93.0	95.0
SHH Np/Cholesterol/BOC	-0.034	0.054	0.115	1.0	-0.181	40.0	41.0
SHH Np/Cholesterol/CDO	-0.035	0.059	0.115	1.0	-0.188	43.0	44.0
mesenchymal cell differentiation	0.109	0.103	0.203	179.0	-0.114	1.0	180.0
mol:Vitamin D3	-0.094	0.154	0.4	4.0	-0.333	49.0	53.0
IHH N/PTCH2	-0.099	0.131	0.212	4.0	-0.214	193.0	197.0
CDON	0.013	0.05	-9999.0	0.0	-0.335	7.0	7.0
IHH N/PTCH1	-0.097	0.172	0.271	2.0	-0.256	164.0	166.0
Megalin/LRPAP1	-0.037	0.117	0.238	1.0	-0.235	90.0	91.0
PTCH2	0.02	0.019	-9999.0	0.0	-0.335	1.0	1.0
SHH Np/Cholesterol	-0.03	0.054	-9999.0	0.0	-0.176	42.0	42.0
PTCH1	-0.107	0.16	0.232	2.0	-0.254	164.0	166.0
HHIP	-0.173	0.177	-9999.0	0.0	-0.335	192.0	192.0