Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.065 0.188 0.492 34.0 -9999.0 0.0 34.0 KIRREL -0.031 0.157 -9999.0 0.0 -0.681 12.0 12.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.065 0.189 -9999.0 0.0 -0.493 34.0 34.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.061 0.145 -9999.0 0.0 -0.471 14.0 14.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.017 0.108 -9999.0 0.0 -0.438 5.0 5.0 FYN -0.043 0.141 -9999.0 0.0 -0.432 15.0 15.0 mol:Ca2+ -0.061 0.144 -9999.0 0.0 -0.466 14.0 14.0 mol:DAG -0.061 0.145 -9999.0 0.0 -0.469 14.0 14.0 NPHS2 -0.016 0.086 -9999.0 0.0 -0.625 4.0 4.0 mol:IP3 -0.061 0.145 -9999.0 0.0 -0.469 14.0 14.0 regulation of endocytosis -0.033 0.134 -9999.0 0.0 -0.426 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.062 0.148 -9999.0 0.0 -0.38 36.0 36.0 establishment of cell polarity -0.065 0.188 -9999.0 0.0 -0.492 34.0 34.0 Nephrin/NEPH1/podocin/NCK1-2 -0.032 0.142 -9999.0 0.0 -0.6 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.033 0.136 -9999.0 0.0 -0.432 12.0 12.0 NPHS1 -0.064 0.196 -9999.0 0.0 -0.61 25.0 25.0 Nephrin/NEPH1/podocin -0.043 0.142 -9999.0 0.0 -0.434 15.0 15.0 TJP1 0.009 0.046 -9999.0 0.0 -0.671 1.0 1.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.061 0.145 -9999.0 0.0 -0.471 14.0 14.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.061 0.145 -9999.0 0.0 -0.471 14.0 14.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.063 0.167 -9999.0 0.0 -0.413 29.0 29.0 cytoskeleton organization -0.022 0.134 -9999.0 0.0 -0.551 5.0 5.0 Nephrin/NEPH1 -0.046 0.139 -9999.0 0.0 -0.358 34.0 34.0 Nephrin/NEPH1/ZO-1 -0.063 0.15 -9999.0 0.0 -0.396 35.0 35.0