Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.004 0.101 0.383 11.0 -9999.0 0.0 11.0 KIRREL -0.004 0.115 -9999.0 0.0 -0.521 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.004 0.101 -9999.0 0.0 -0.384 11.0 11.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.018 0.088 -9999.0 0.0 -0.303 10.0 10.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.06 -9999.0 0.0 -0.262 8.0 8.0 FYN -0.01 0.095 0.291 6.0 -0.28 11.0 17.0 mol:Ca2+ 0.016 0.084 -9999.0 0.0 -0.302 9.0 9.0 mol:DAG 0.016 0.085 -9999.0 0.0 -0.304 9.0 9.0 NPHS2 -0.015 0.035 -9999.0 0.0 -0.186 4.0 4.0 mol:IP3 0.016 0.085 -9999.0 0.0 -0.304 9.0 9.0 regulation of endocytosis 0.014 0.08 -9999.0 0.0 -0.267 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol 0.006 0.081 -9999.0 0.0 -0.3 10.0 10.0 establishment of cell polarity -0.004 0.101 -9999.0 0.0 -0.383 11.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 0.023 0.083 -9999.0 0.0 -0.275 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 0.016 0.081 -9999.0 0.0 -0.27 11.0 11.0 NPHS1 -0.012 0.067 -9999.0 0.0 -0.185 24.0 24.0 Nephrin/NEPH1/podocin 0.009 0.08 -9999.0 0.0 -0.281 11.0 11.0 TJP1 0.025 0.036 -9999.0 0.0 -0.51 1.0 1.0 NCK1 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.017 0.086 -9999.0 0.0 -0.305 9.0 9.0 CD2AP 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.018 0.088 -9999.0 0.0 -0.303 10.0 10.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.017 0.1 0.289 7.0 -0.283 11.0 18.0 cytoskeleton organization -0.017 0.069 0.197 2.0 -0.306 8.0 10.0 Nephrin/NEPH1 0.002 0.072 -9999.0 0.0 -0.269 11.0 11.0 Nephrin/NEPH1/ZO-1 0.012 0.091 -9999.0 0.0 -0.322 11.0 11.0