Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.031	0.209	0.503	81.0	-0.451	15.0	96.0
IHH	-0.005	0.078	0.161	88.0	-9999.0	0.0	88.0
SHH Np/Cholesterol/GAS1	-0.044	0.037	0.144	1.0	-0.131	76.0	77.0
LRPAP1	0.028	0.007	-9999.0	0.0	0.0	37.0	37.0
dorsoventral neural tube patterning	0.044	0.037	0.13	76.0	-0.142	1.0	77.0
SMO/beta Arrestin2	0.025	0.132	0.298	83.0	-0.387	8.0	91.0
SMO	0.028	0.133	0.308	83.0	-0.396	8.0	91.0
AKT1	-0.025	0.147	0.33	2.0	-0.441	19.0	21.0
ARRB2	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0
BOC	0.025	0.01	-9999.0	0.0	0.0	80.0	80.0
ADRBK1	0.029	0.003	-9999.0	0.0	0.0	7.0	7.0
heart looping	0.028	0.133	0.307	83.0	-0.391	8.0	91.0
STIL	0.002	0.065	0.273	20.0	-9999.0	0.0	20.0
DHH N/PTCH2	0.042	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.006	0.134	0.315	79.0	-0.292	7.0	86.0
PIK3CA	0.021	0.014	-9999.0	0.0	0.0	171.0	171.0
DHH	0.029	0.003	-9999.0	0.0	0.0	5.0	5.0
PTHLH	0.032	0.194	0.496	71.0	-0.441	1.0	72.0
determination of left/right symmetry	0.028	0.133	0.307	83.0	-0.391	8.0	91.0
PIK3R1	0.021	0.013	-9999.0	0.0	0.0	161.0	161.0
skeletal system development	0.032	0.193	0.495	71.0	-0.438	1.0	72.0
IHH N/Hhip	0.049	0.042	0.181	3.0	-9999.0	0.0	3.0
DHH N/Hhip	0.042	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.028	0.133	0.307	83.0	-0.391	8.0	91.0
pancreas development	0.028	0.006	-9999.0	0.0	0.0	27.0	27.0
HHAT	0.029	0.005	-9999.0	0.0	0.0	18.0	18.0
PI3K	-0.0	0.067	-9999.0	0.0	-0.163	75.0	75.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.025	0.011	-9999.0	0.0	0.0	95.0	95.0
somite specification	0.028	0.133	0.307	83.0	-0.391	8.0	91.0
SHH Np/Cholesterol/PTCH1	-0.002	0.115	0.269	75.0	-0.267	7.0	82.0
SHH Np/Cholesterol/PTCH2	-0.032	0.016	0.144	1.0	-0.13	5.0	6.0
SHH Np/Cholesterol/Megalin	-0.025	0.018	-9999.0	0.0	-0.13	4.0	4.0
SHH	-0.03	0.014	0.195	1.0	-9999.0	0.0	1.0
catabolic process	0.023	0.158	0.38	84.0	-0.318	7.0	91.0
SMO/Vitamin D3	0.004	0.121	0.261	76.0	-0.362	8.0	84.0
SHH Np/Cholesterol/Hhip	-0.031	0.017	0.144	1.0	-0.13	5.0	6.0
LRP2	0.022	0.013	-9999.0	0.0	0.0	141.0	141.0
receptor-mediated endocytosis	0.025	0.125	0.28	74.0	-0.397	7.0	81.0
SHH Np/Cholesterol/BOC	-0.04	0.032	0.144	1.0	-0.13	55.0	56.0
SHH Np/Cholesterol/CDO	-0.032	0.018	0.144	1.0	-0.13	7.0	8.0
mesenchymal cell differentiation	0.031	0.016	0.129	5.0	-0.142	1.0	6.0
mol:Vitamin D3	0.005	0.119	0.262	75.0	-0.268	7.0	82.0
IHH N/PTCH2	0.05	0.041	0.181	4.0	-9999.0	0.0	4.0
CDON	0.028	0.007	-9999.0	0.0	0.0	33.0	33.0
IHH N/PTCH1	-0.034	0.052	-9999.0	0.0	-0.306	9.0	9.0
Megalin/LRPAP1	0.03	0.023	-9999.0	0.0	-0.163	2.0	2.0
PTCH2	0.029	0.006	-9999.0	0.0	0.0	22.0	22.0
SHH Np/Cholesterol	-0.022	0.013	0.156	1.0	-0.119	5.0	6.0
PTCH1	0.023	0.159	0.38	84.0	-0.319	7.0	91.0
HHIP	0.028	0.006	-9999.0	0.0	0.0	27.0	27.0