Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.081 0.172 0.457 34.0 -9999.0 0.0 34.0 KIRREL -0.003 0.043 -9999.0 0.0 -0.438 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.081 0.172 -9999.0 0.0 -0.458 34.0 34.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.053 0.134 -9999.0 0.0 -0.362 33.0 33.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.03 0.107 -9999.0 0.0 -0.304 26.0 26.0 FYN -0.056 0.129 -9999.0 0.0 -0.345 35.0 35.0 mol:Ca2+ -0.065 0.127 -9999.0 0.0 -0.359 33.0 33.0 mol:DAG -0.053 0.134 -9999.0 0.0 -0.361 33.0 33.0 NPHS2 -0.018 0.07 -9999.0 0.0 -0.417 7.0 7.0 mol:IP3 -0.053 0.134 -9999.0 0.0 -0.361 33.0 33.0 regulation of endocytosis -0.045 0.122 -9999.0 0.0 -0.32 35.0 35.0 Nephrin/NEPH1/podocin/Cholesterol -0.061 0.134 -9999.0 0.0 -0.369 33.0 33.0 establishment of cell polarity -0.081 0.172 -9999.0 0.0 -0.457 34.0 34.0 Nephrin/NEPH1/podocin/NCK1-2 -0.041 0.124 -9999.0 0.0 -0.326 33.0 33.0 Nephrin/NEPH1/beta Arrestin2 -0.045 0.124 -9999.0 0.0 -0.324 35.0 35.0 NPHS1 -0.118 0.228 -9999.0 0.0 -0.499 65.0 65.0 Nephrin/NEPH1/podocin -0.056 0.13 -9999.0 0.0 -0.347 35.0 35.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.053 0.134 -9999.0 0.0 -0.362 33.0 33.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.053 0.134 -9999.0 0.0 -0.362 33.0 33.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.057 0.129 -9999.0 0.0 -0.335 37.0 37.0 cytoskeleton organization -0.038 0.133 -9999.0 0.0 -0.378 28.0 28.0 Nephrin/NEPH1 -0.055 0.123 -9999.0 0.0 -0.349 29.0 29.0 Nephrin/NEPH1/ZO-1 -0.055 0.139 -9999.0 0.0 -0.389 28.0 28.0