Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.035 0.119 0.441 11.0 -9999.0 0.0 11.0 KIRREL -0.021 0.136 -9999.0 0.0 -0.613 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.035 0.119 -9999.0 0.0 -0.442 11.0 11.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.025 0.086 -9999.0 0.0 -0.331 7.0 7.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.006 0.072 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.008 0.084 -9999.0 0.0 -0.315 7.0 7.0 mol:Ca2+ -0.025 0.085 -9999.0 0.0 -0.329 7.0 7.0 mol:DAG -0.025 0.086 -9999.0 0.0 -0.33 7.0 7.0 NPHS2 -0.001 0.015 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.025 0.086 -9999.0 0.0 -0.33 7.0 7.0 regulation of endocytosis -0.013 0.077 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.026 0.088 -9999.0 0.0 -0.326 11.0 11.0 establishment of cell polarity -0.035 0.119 -9999.0 0.0 -0.441 11.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 -0.022 0.077 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.0 0.081 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.013 0.098 -9999.0 0.0 -0.579 4.0 4.0 Nephrin/NEPH1/podocin -0.014 0.084 -9999.0 0.0 -0.316 7.0 7.0 TJP1 0.007 0.05 -9999.0 0.0 -0.584 1.0 1.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.025 0.086 -9999.0 0.0 -0.331 7.0 7.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.025 0.086 -9999.0 0.0 -0.331 7.0 7.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.071 0.171 -9999.0 0.0 -0.387 26.0 26.0 cytoskeleton organization 0.009 0.085 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.025 0.085 -9999.0 0.0 -0.315 11.0 11.0 Nephrin/NEPH1/ZO-1 -0.03 0.098 -9999.0 0.0 -0.35 12.0 12.0