Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.034 0.173 0.454 1.0 -0.467 9.0 10.0 MAP3K8 0.001 0.106 -9999.0 0.0 -0.46 7.0 7.0 FOS -0.029 0.14 0.505 1.0 -0.382 9.0 10.0 PRKCA 0.014 0.06 -9999.0 0.0 -0.459 2.0 2.0 PTPN7 0.013 0.049 -9999.0 0.0 -0.247 4.0 4.0 HRAS 0.025 0.023 -9999.0 0.0 -0.236 1.0 1.0 PRKCB -0.072 0.19 -9999.0 0.0 -0.459 27.0 27.0 NRAS 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.04 0.029 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.006 0.087 -9999.0 0.0 -0.501 1.0 1.0 MAP2K1 -0.072 0.198 -9999.0 0.0 -0.431 26.0 26.0 ELK1 0.02 0.021 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.055 0.167 -9999.0 0.0 -0.41 23.0 23.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 20.0 20.0 MAPK1 -0.013 0.096 -9999.0 0.0 -0.42 3.0 3.0 RAF1 -0.066 0.174 -9999.0 0.0 -0.404 27.0 27.0 KRAS 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0