Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.033 0.118 0.324 10.0 -9999.0 0.0 10.0 KIRREL -0.013 0.099 -9999.0 0.0 -0.485 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.033 0.118 -9999.0 0.0 -0.324 10.0 10.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.047 0.137 -9999.0 0.0 -0.337 10.0 10.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.069 -9999.0 0.0 -0.246 3.0 3.0 FYN -0.021 0.089 -9999.0 0.0 -0.221 10.0 10.0 mol:Ca2+ -0.018 0.096 -9999.0 0.0 -0.312 3.0 3.0 mol:DAG -0.018 0.097 -9999.0 0.0 -0.313 3.0 3.0 NPHS2 -0.014 0.078 -9999.0 0.0 -0.464 2.0 2.0 mol:IP3 -0.018 0.097 -9999.0 0.0 -0.313 3.0 3.0 regulation of endocytosis -0.012 0.085 -9999.0 0.0 -0.271 3.0 3.0 Nephrin/NEPH1/podocin/Cholesterol -0.025 0.097 -9999.0 0.0 -0.245 11.0 11.0 establishment of cell polarity -0.033 0.118 -9999.0 0.0 -0.324 10.0 10.0 Nephrin/NEPH1/podocin/NCK1-2 -0.008 0.089 -9999.0 0.0 -0.387 1.0 1.0 Nephrin/NEPH1/beta Arrestin2 -0.011 0.086 -9999.0 0.0 -0.273 3.0 3.0 NPHS1 -0.037 0.136 -9999.0 0.0 -0.45 7.0 7.0 Nephrin/NEPH1/podocin -0.02 0.09 -9999.0 0.0 -0.221 10.0 10.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.017 0.097 -9999.0 0.0 -0.315 3.0 3.0 CD2AP -0.038 0.152 -9999.0 0.0 -0.502 7.0 7.0 Nephrin/NEPH1/podocin/GRB2 -0.017 0.097 -9999.0 0.0 -0.315 3.0 3.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.02 0.091 -9999.0 0.0 -0.271 4.0 4.0 cytoskeleton organization -0.002 0.082 -9999.0 0.0 -0.295 2.0 2.0 Nephrin/NEPH1 -0.02 0.082 -9999.0 0.0 -0.222 10.0 10.0 Nephrin/NEPH1/ZO-1 -0.016 0.093 -9999.0 0.0 -0.247 10.0 10.0