Clinical Features	Time to Death		AGE		GENDER	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q
BRAF	69 (50%)	70	0.12268	1	0.050311	1	1	1
NRAS	43 (31%)	96	0.79986	1	0.16393	1	0.84998	1
CDKN2A	21 (15%)	118	0.63774	1	0.53204	1	1	1
TP53	25 (18%)	114	0.46437	1	0.098492	1	0.81928	1
PTEN	9 (6%)	130	0.85684	1	0.7977	1	0.72457	1
ACSM2B	28 (20%)	111	0.14555	1	0.95248	1	0.0076412	1
LCE1B	9 (6%)	130	0.5864	1	0.67111	1	0.72457	1
CADM2	15 (11%)	124	0.79161	1	0.88795	1	1	1
NAP1L2	12 (9%)	127	0.68871	1	0.07326	1	0.75894	1
RAC1	11 (8%)	128	0.04286	1	0.53698	1	1	1
MUC7	11 (8%)	128	0.49479	1	0.00021091	0.0941	0.74604	1
OR51S1	16 (12%)	123	0.41481	1	0.54011	1	1	1
FUT9	16 (12%)	123	0.95443	1	0.027831	1	1	1
PPP6C	13 (9%)	126	0.038488	1	0.76653	1	0.76805	1
USP29	25 (18%)	114	0.045635	1	0.091961	1	0.36704	1
RPTN	22 (16%)	117	0.54493	1	0.37292	1	0.80994	1
TAF1A	8 (6%)	131	0.27479	1	0.57656	1	0.46475	1
CDH9	25 (18%)	114	0.3328	1	0.46891	1	1	1
GRXCR1	14 (10%)	125	0.40459	1	0.018754	1	0.57333	1
HIST1H2AA	7 (5%)	132	0.90114	1	0.99018	1	0.70724	1
ZNF679	14 (10%)	125	0.95234	1	0.43443	1	0.57333	1
C8A	17 (12%)	122	0.0045404	1	0.0042949	1	0.029861	1
RBM11	10 (7%)	129	0.68982	1	0.28751	1	0.74576	1
ZNF479	12 (9%)	127	0.36035	1	0.089551	1	0.75894	1
GFRAL	20 (14%)	119	0.47307	1	0.64275	1	1	1
DDX3X	15 (11%)	124	0.61316	1	0.46724	1	0.25582	1
OR4M2	16 (12%)	123	0.64964	1	0.085877	1	1	1
FRG2B	10 (7%)	129	0.50265	1	0.022844	1	0.49758	1
PDE1A	23 (17%)	116	0.30864	1	0.16214	1	1	1
PRB2	21 (15%)	118	0.54752	1	0.012861	1	0.086666	1
LUZP2	12 (9%)	127	0.65142	1	0.90812	1	0.75894	1
NRK	18 (13%)	121	0.33956	1	0.82137	1	0.8003	1
PARM1	11 (8%)	128	0.0085136	1	0.21446	1	1	1
SLC38A4	16 (12%)	123	0.7855	1	0.3521	1	0.16782	1
PRAMEF11	12 (9%)	127	0.18731	1	0.15073	1	0.75894	1
USP17L2	13 (9%)	126	0.64	1	0.92783	1	0.37308	1
PRB1	12 (9%)	127	0.3303	1	0.554	1	0.21011	1
CYLC2	16 (12%)	123	0.61631	1	0.10355	1	0.78516	1
DSG3	33 (24%)	106	0.64941	1	0.13408	1	0.41618	1
VEGFC	11 (8%)	128	0.94284	1	0.41432	1	1	1
IL32	5 (4%)	134	0.026289	1	0.4844	1	1	1
LILRB4	21 (15%)	118	0.23969	1	0.38457	1	0.80971	1
GLRB	15 (11%)	124	0.47763	1	0.11353	1	1	1
STXBP5L	29 (21%)	110	0.12011	1	0.53794	1	0.52335	1
GML	8 (6%)	131	0.93224	1	0.11687	1	0.25775	1
TLL1	30 (22%)	109	0.37261	1	0.23518	1	0.5216	1
DEFB118	6 (4%)	133	0.14069	1	0.43489	1	1	1
GK2	17 (12%)	122	0.1988	1	0.96751	1	1	1
OR5J2	10 (7%)	129	0.82353	1	0.94244	1	0.17097	1
LIN7A	8 (6%)	131	0.41162	1	0.73555	1	0.7102	1
MUM1L1	13 (9%)	126	0.35696	1	0.54982	1	0.76805	1
MARCH11	7 (5%)	132	0.33572	1	0.95426	1	1	1
PSG4	15 (11%)	124	0.96949	1	0.46186	1	0.78283	1
ZIM3	12 (9%)	127	0.046827	1	0.9678	1	0.53514	1
CLEC14A	14 (10%)	125	0.26167	1	0.90545	1	0.25535	1
OR5H2	11 (8%)	128	0.42069	1	0.032039	1	0.53177	1
TCEB3C	20 (14%)	119	0.50792	1	0.14797	1	0.042891	1
PRB4	16 (12%)	123	0.13748	1	0.2629	1	0.41163	1
KLHL4	14 (10%)	125	0.14693	1	0.666	1	0.3808	1
OR52J3	8 (6%)	131	0.14857	1	0.42464	1	1	1
HBD	8 (6%)	131	0.083258	1	0.63162	1	0.46475	1
FAM19A1	7 (5%)	132	0.33835	1	0.97844	1	0.70724	1
LRRIQ4	14 (10%)	125	0.44931	1	0.15192	1	0.3808	1
SPINK13	4 (3%)	135	0.18212	1	0.341	1	1	1
SNAP91	17 (12%)	122	0.91313	1	0.068689	1	0.28945	1
LONRF2	10 (7%)	129	0.075122	1	0.88844	1	0.74576	1
CLCC1	7 (5%)	132	0.12707	1	0.5403	1	1	1
KIAA1257	7 (5%)	132	0.082432	1	0.029329	1	0.42261	1
SIGLEC14	6 (4%)	133	0.87198	1	0.16453	1	0.085377	1
SPANXN2	12 (9%)	127	0.028334	1	0.77553	1	0.53514	1
DEFB112	5 (4%)	134	0.30705	1	0.28225	1	1	1
CD2	14 (10%)	125	0.59165	1	0.35703	1	0.77091	1
HTR3B	9 (6%)	130	0.055799	1	0.88868	1	0.15443	1
KIR2DL1	9 (6%)	130	0.41211	1	0.35449	1	0.72457	1
OR4N2	17 (12%)	122	0.83248	1	0.37263	1	0.029861	1
ST18	27 (19%)	112	0.79123	1	0.3873	1	0.82482	1
TUBB8	7 (5%)	132	0.89773	1	0.20233	1	1	1
C2ORF40	4 (3%)	135	0.73238	1	0.41377	1	0.62418	1
PRR23B	9 (6%)	130	0.37434	1	0.42148	1	0.72457	1
TFEC	12 (9%)	127	0.19878	1	0.032941	1	0.75894	1
SGCZ	15 (11%)	124	0.079346	1	0.86786	1	1	1
TRAT1	9 (6%)	130	0.04	1	0.6807	1	0.72457	1
TRIM58	12 (9%)	127	0.41548	1	0.0026796	1	1	1
ANXA10	9 (6%)	130	0.34593	1	0.24815	1	0.48565	1
ZNF844	4 (3%)	135	0.42611	1	0.019847	1	0.62418	1
SLC14A1	10 (7%)	129	0.69286	1	0.12865	1	0.013576	1
C9	11 (8%)	128	0.4617	1	0.89724	1	0.53177	1
DSG1	21 (15%)	118	0.10481	1	0.39651	1	1	1
CCDC11	13 (9%)	126	0.78341	1	0.96249	1	1	1
MKX	10 (7%)	129	0.47634	1	0.83701	1	0.74576	1
OR7D2	13 (9%)	126	0.92535	1	0.52191	1	0.37308	1
STARD6	5 (4%)	134	0.84821	1	0.044599	1	1	1
SPATA8	5 (4%)	134	0.57613	1	0.0871	1	0.35624	1
GRXCR2	11 (8%)	128	0.38036	1	0.7562	1	1	1
OR4A15	14 (10%)	125	0.98338	1	0.04846	1	0.082676	1
C4ORF22	8 (6%)	131	0.28106	1	0.61441	1	0.7102	1
CCDC54	10 (7%)	129	0.46766	1	0.6985	1	0.32482	1
CRISP2	8 (6%)	131	0.9551	1	0.094335	1	0.46475	1
MOG	6 (4%)	133	0.86555	1	0.065899	1	0.41441	1
NMS	7 (5%)	132	0.94823	1	0.16944	1	0.70724	1
DEFB115	5 (4%)	134	0.9348	1	0.51482	1	0.15797	1
UGT2A3	12 (9%)	127	0.99866	1	0.47553	1	0.53514	1
ZNF98	12 (9%)	127	0.15958	1	0.82614	1	0.75894	1
ADH1C	22 (16%)	117	0.62751	1	0.24248	1	0.80994	1
HBG2	6 (4%)	133	0.62626	1	0.25375	1	1	1
HHLA2	9 (6%)	130	0.64926	1	0.3326	1	1	1
IDH1	7 (5%)	132	0.80241	1	0.011598	1	0.26061	1
OR2L3	10 (7%)	129	0.47658	1	0.70255	1	0.74576	1
OR4F6	10 (7%)	129	0.16567	1	0.31386	1	0.32482	1
B2M	4 (3%)	135	0.68469	1	0.38817	1	0.29643	1
ARID2	20 (14%)	119	0.2205	1	0.15081	1	0.31878	1
LOC649330	16 (12%)	123	0.28764	1	0.022614	1	0.78516	1
OR5AC2	14 (10%)	125	0.91643	1	0.76366	1	0.57333	1
OR5H14	7 (5%)	132	0.35721	1	0.83029	1	0.047177	1
SPAG16	12 (9%)	127	0.2515	1	0.51098	1	0.21011	1
SPRY3	8 (6%)	131	0.27319	1	0.28917	1	1	1
STK31	22 (16%)	117	0.8245	1	0.71055	1	1	1
TACR3	13 (9%)	126	0.17841	1	0.95064	1	0.76805	1
SERPINB4	18 (13%)	121	0.96902	1	0.15263	1	0.069496	1
TSGA13	6 (4%)	133	0.30744	1	0.90764	1	0.41441	1
GIMAP7	11 (8%)	128	0.81583	1	0.082753	1	0.32798	1
SDR16C5	18 (13%)	121	0.60339	1	0.12062	1	0.44607	1
SPOCK3	16 (12%)	123	0.73921	1	0.56504	1	0.050696	1
TRHR	15 (11%)	124	0.15413	1	0.37742	1	1	1
CD96	10 (7%)	129	0.92007	1	0.45085	1	1	1
CLEC4E	10 (7%)	129	0.44731	1	0.24546	1	0.49758	1
TPTE	36 (26%)	103	0.70177	1	0.19878	1	0.69114	1
MCART6	7 (5%)	132	0.7626	1	0.077018	1	1	1
OR2W1	12 (9%)	127	0.72635	1	0.079936	1	0.35658	1
MORF4	10 (7%)	129	0.52675	1	0.8293	1	0.74576	1
RGS18	7 (5%)	132	0.98087	1	0.35017	1	0.047177	1
BAGE2	9 (6%)	130	0.80636	1	0.91647	1	0.72457	1
KIAA1644	4 (3%)	135	0.38773	1	0.24032	1	1	1
AGXT2	14 (10%)	125	0.20538	1	0.45168	1	1	1
CLDN4	7 (5%)	132	0.91395	1	0.053154	1	0.70724	1
CDH10	21 (15%)	118	0.02744	1	0.9897	1	0.80971	1
VWC2L	11 (8%)	128	0.77674	1	0.88368	1	1	1
ABRA	10 (7%)	129	0.073761	1	0.062017	1	0.32482	1
ARPP21	23 (17%)	116	0.1255	1	0.080916	1	0.15436	1
NR1H4	8 (6%)	131	0.37023	1	0.28727	1	0.7102	1
GZMA	8 (6%)	131	0.96448	1	0.37641	1	0.7102	1
DGAT2L6	8 (6%)	131	0.50405	1	0.45877	1	1	1
TMCO5A	6 (4%)	133	0.39229	1	0.27545	1	0.41441	1
KRT26	7 (5%)	132	6.8647e-06	0.00307	0.74108	1	1	1
CCNE2	7 (5%)	132	0.13626	1	0.72961	1	0.70724	1
CCK	5 (4%)	134	0.12792	1	0.74356	1	0.65202	1
ADAMTS20	35 (25%)	104	0.39135	1	0.12996	1	0.31228	1
MPP7	17 (12%)	122	0.86025	1	0.024869	1	0.59856	1
FAM155A	9 (6%)	130	0.19322	1	0.59491	1	0.28812	1