Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p34.2) 45 (30%) 105 0.00019969 0.0943 4.0864e-05 0.0199 0.89402 1 1 1 0.014691 1 0.51983 1 0.4596 1 0.051214 1 Amp Peak 2(1q21.3) 76 (51%) 74 6.85e-06 0.00337 0.00039988 0.187 0.011755 1 0.00635 1 0.0037395 1 0.36547 1 0.27025 1 0.0020646 0.906 Amp Peak 3(1q23.3) 82 (55%) 68 2.5929e-05 0.0127 0.012382 1 0.9254 1 0.68055 1 0.063352 1 0.71896 1 0.001037 0.471 0.0011876 0.534 Amp Peak 4(3p25.2) 72 (48%) 78 3.3553e-05 0.0163 0.0016134 0.72 0.27822 1 0.2373 1 0.00084835 0.388 0.0003715 0.174 0.0028882 1 0.00042236 0.197 Amp Peak 5(3q26.32) 84 (56%) 66 0.0044027 1 0.66438 1 0.16067 1 0.20572 1 0.60054 1 0.87483 1 0.53477 1 0.52538 1 Amp Peak 6(4p16.3) 31 (21%) 119 0.017605 1 0.1717 1 0.16214 1 0.13656 1 0.10257 1 0.11838 1 0.053135 1 0.56582 1 Amp Peak 7(4q13.3) 23 (15%) 127 8.4547e-05 0.0406 0.15965 1 0.51704 1 1 1 0.57148 1 0.39991 1 0.37821 1 0.6822 1 Amp Peak 8(5p15.1) 69 (46%) 81 4.4953e-05 0.0218 0.20229 1 0.013987 1 0.33188 1 0.094042 1 0.45769 1 0.14338 1 0.25481 1 Amp Peak 9(6p22.3) 61 (41%) 89 0.00018288 0.0865 0.0023585 1 0.83415 1 0.76099 1 0.55965 1 0.58141 1 0.24072 1 0.32338 1 Amp Peak 10(6q12) 25 (17%) 125 0.0060126 1 0.62748 1 1 1 0.84195 1 1 1 0.66707 1 0.17286 1 1 1 Amp Peak 11(6q21) 18 (12%) 132 0.24512 1 0.05116 1 0.62114 1 0.44988 1 0.19838 1 0.15454 1 0.73488 1 0.76716 1 Amp Peak 12(7p11.2) 78 (52%) 72 4.4909e-07 0.000224 0.0020026 0.883 0.48139 1 0.18619 1 0.82484 1 0.67802 1 0.62169 1 0.88995 1 Amp Peak 13(8p11.23) 48 (32%) 102 0.00049153 0.228 0.048781 1 0.073189 1 0.022922 1 0.42305 1 0.27108 1 0.078607 1 0.10488 1 Amp Peak 14(8p11.21) 48 (32%) 102 1.6173e-05 0.00794 0.014559 1 0.59619 1 0.52776 1 0.26825 1 0.44823 1 0.27024 1 0.1358 1 Amp Peak 15(8q22.3) 92 (61%) 58 0.0040913 1 0.0020564 0.905 0.16764 1 0.4202 1 0.10839 1 0.43684 1 0.038071 1 0.27285 1 Amp Peak 16(8q24.21) 88 (59%) 62 0.0013776 0.616 0.021955 1 0.22617 1 0.62289 1 0.12541 1 0.19638 1 0.074887 1 0.20723 1 Amp Peak 17(10p15.1) 61 (41%) 89 6.729e-09 3.38e-06 5.2508e-06 0.00259 0.89314 1 0.72506 1 0.22073 1 0.058297 1 0.46805 1 0.13162 1 Amp Peak 18(11q13.3) 59 (39%) 91 0.0016929 0.752 0.23702 1 0.5536 1 0.64834 1 0.22237 1 0.31929 1 0.017553 1 0.88738 1 Amp Peak 19(12q15) 48 (32%) 102 0.050913 1 0.10718 1 0.76019 1 0.71714 1 0.0081952 1 0.0021946 0.961 0.027458 1 0.1312 1 Amp Peak 20(13q22.1) 49 (33%) 101 0.58019 1 0.65884 1 0.64121 1 0.091166 1 0.88569 1 0.89845 1 0.44567 1 0.42454 1 Amp Peak 21(16p12.1) 39 (26%) 111 0.010368 1 0.11247 1 0.078326 1 0.15156 1 0.90043 1 0.84647 1 0.27062 1 0.32861 1 Amp Peak 22(17q11.2) 68 (45%) 82 4.6173e-08 2.31e-05 0.0012197 0.548 0.76019 1 0.67251 1 0.0001339 0.0639 0.0031839 1 0.015514 1 0.13343 1 Amp Peak 23(17q12) 63 (42%) 87 0.0018998 0.842 0.15321 1 0.9394 1 0.67251 1 0.05045 1 0.25997 1 0.0078267 1 0.00082054 0.376 Amp Peak 24(19q12) 65 (43%) 85 6.3489e-06 0.00313 0.0027118 1 0.37007 1 0.68055 1 0.4558 1 0.43786 1 0.29008 1 0.2111 1 Amp Peak 25(19q13.43) 63 (42%) 87 9.0782e-05 0.0435 0.025791 1 0.77788 1 0.77196 1 0.081185 1 0.81907 1 0.13705 1 0.095744 1 Amp Peak 26(20q11.21) 104 (69%) 46 0.00069982 0.321 0.42783 1 0.34208 1 0.52334 1 0.20399 1 0.22575 1 0.35237 1 0.093794 1 Amp Peak 27(22q11.23) 35 (23%) 115 0.0013077 0.586 0.38329 1 0.83664 1 0.17219 1 0.14625 1 0.23153 1 0.34 1 0.32269 1 Del Peak 1(1p36.11) 27 (18%) 123 0.96736 1 0.0049925 1 0.069891 1 0.082591 1 0.21564 1 0.18112 1 0.84224 1 0.88053 1 Del Peak 2(1q32.1) 28 (19%) 122 0.07233 1 0.11463 1 0.73836 1 0.22864 1 0.28241 1 0.11132 1 0.70227 1 0.55838 1 Del Peak 3(2q22.1) 43 (29%) 107 0.0031733 1 0.29465 1 0.3152 1 0.31458 1 0.57724 1 0.10238 1 0.37593 1 0.63079 1 Del Peak 4(2q34) 60 (40%) 90 3.5259e-06 0.00175 0.13729 1 0.3093 1 0.3197 1 0.15195 1 0.11116 1 0.09042 1 0.058568 1 Del Peak 5(2q37.1) 73 (49%) 77 3.2969e-05 0.0161 0.012785 1 0.90782 1 0.93591 1 0.06586 1 0.018377 1 0.040151 1 0.031428 1 Del Peak 6(3p21.31) 47 (31%) 103 0.00039436 0.185 0.12029 1 0.0064897 1 0.068072 1 0.00055753 0.257 0.020288 1 0.078896 1 0.16461 1 Del Peak 7(3p14.2) 48 (32%) 102 0.000507 0.234 0.56029 1 0.075854 1 0.015843 1 0.00042488 0.198 0.0075294 1 0.13203 1 0.64462 1 Del Peak 8(3p12.3) 41 (27%) 109 0.012731 1 0.45467 1 0.018856 1 0.018111 1 0.0016441 0.732 0.052339 1 0.22134 1 0.49553 1 Del Peak 9(4q22.1) 59 (39%) 91 0.53909 1 0.62787 1 0.3577 1 0.68037 1 0.2965 1 0.14893 1 0.74178 1 0.85158 1 Del Peak 10(4q34.2) 65 (43%) 85 0.065426 1 0.37403 1 0.42198 1 0.1513 1 0.52653 1 0.033339 1 0.24204 1 0.45493 1 Del Peak 11(5q11.2) 75 (50%) 75 0.001051 0.475 0.051099 1 0.8138 1 0.48698 1 0.73893 1 0.090612 1 0.19545 1 0.029113 1 Del Peak 12(5q35.1) 72 (48%) 78 0.022817 1 0.0060952 1 0.56722 1 0.81467 1 0.60958 1 0.21445 1 0.050701 1 0.1233 1 Del Peak 13(6p25.3) 40 (27%) 110 0.020667 1 0.26872 1 0.13456 1 0.49135 1 0.51234 1 0.82396 1 0.60162 1 1 1 Del Peak 14(6q21) 63 (42%) 87 7.2861e-07 0.000363 0.012898 1 0.079914 1 0.12261 1 0.31418 1 0.015304 1 0.41236 1 0.11707 1 Del Peak 15(6q27) 62 (41%) 88 2.0443e-06 0.00102 0.0023544 1 0.1565 1 0.16257 1 0.22073 1 0.0062481 1 0.22936 1 0.16828 1 Del Peak 16(8p23.3) 80 (53%) 70 2.103e-08 1.06e-05 5.2414e-05 0.0253 0.14489 1 0.32464 1 0.16869 1 0.96879 1 0.094501 1 0.017958 1 Del Peak 17(8p21.1) 84 (56%) 66 1.5307e-09 7.71e-07 5.1974e-05 0.0251 0.14489 1 0.32464 1 0.71307 1 0.49814 1 0.030864 1 0.051578 1 Del Peak 18(9p23) 65 (43%) 85 0.0019894 0.879 0.87362 1 0.27398 1 0.27535 1 0.46018 1 0.06327 1 0.50082 1 0.10853 1 Del Peak 19(9p21.3) 86 (57%) 64 0.0004823 0.224 0.56608 1 0.071796 1 0.57543 1 0.25138 1 0.12762 1 0.14987 1 0.20723 1 Del Peak 20(10p12.1) 29 (19%) 121 0.90997 1 0.76928 1 0.45485 1 0.73749 1 0.068631 1 0.02926 1 0.19434 1 1 1 Del Peak 21(10q23.31) 60 (40%) 90 0.010543 1 0.0025019 1 0.2284 1 0.74818 1 0.27708 1 0.045653 1 0.36629 1 0.50755 1 Del Peak 22(11p15.5) 73 (49%) 77 5.1247e-06 0.00254 0.037959 1 0.19518 1 0.72656 1 0.12502 1 0.00015223 0.0722 0.011267 1 0.0088849 1 Del Peak 23(11q25) 47 (31%) 103 4.2645e-05 0.0207 0.33748 1 0.37822 1 0.45365 1 0.19997 1 0.54929 1 0.14267 1 0.294 1 Del Peak 24(13q14.2) 58 (39%) 92 0.00013481 0.0642 0.98586 1 0.00022903 0.108 0.00011695 0.0559 0.092842 1 0.23523 1 0.97302 1 0.13026 1 Del Peak 25(14q12) 43 (29%) 107 0.0008936 0.407 0.00094091 0.428 0.8053 1 0.66312 1 0.14201 1 0.034159 1 0.017125 1 0.0006645 0.306 Del Peak 26(14q32.31) 41 (27%) 109 5.9484e-05 0.0286 0.027201 1 0.8053 1 0.92244 1 0.21839 1 0.24745 1 0.00013579 0.0645 0.0010443 0.473 Del Peak 27(15q13.1) 54 (36%) 96 0.00030099 0.141 0.0031238 1 0.082907 1 0.33188 1 0.5797 1 0.78021 1 0.13461 1 0.11304 1 Del Peak 28(16p13.3) 54 (36%) 96 0.0033236 1 0.0065187 1 0.19141 1 0.6135 1 1 1 0.49891 1 0.79796 1 0.77932 1 Del Peak 29(16q23.1) 38 (25%) 112 1.9895e-05 0.00975 0.043382 1 0.23182 1 0.52044 1 0.61133 1 0.95968 1 0.093165 1 0.083969 1 Del Peak 30(17p12) 77 (51%) 73 2.9136e-08 1.46e-05 0.017517 1 0.55568 1 0.1687 1 0.021805 1 0.02453 1 0.34655 1 0.36323 1 Del Peak 31(18q23) 63 (42%) 87 0.0037721 1 0.48466 1 0.97864 1 0.82167 1 0.84611 1 0.37044 1 0.13218 1 0.24926 1 Del Peak 32(19p13.3) 60 (40%) 90 0.022727 1 0.026551 1 1 1 0.71543 1 0.9439 1 0.083106 1 0.54762 1 0.15946 1 Del Peak 33(22q13.32) 60 (40%) 90 0.0011155 0.503 0.25987 1 0.12831 1 0.0028294 1 0.106 1 0.11469 1 0.50209 1 0.12933 1 Del Peak 34(Xp11.3) 39 (26%) 111 0.19953 1 0.0029406 1 0.77519 1 0.57846 1 0.076659 1 0.23561 1 0.63075 1 0.43876 1 Del Peak 35(Xq21.33) 35 (23%) 115 0.33434 1 0.078904 1 0.17296 1 0.47084 1 0.0091947 1 0.73532 1 0.053632 1 0.433 1 Del Peak 36(Xq22.3) 32 (21%) 118 0.13645 1 0.017277 1 0.14922 1 1 1 0.017407 1 0.79604 1 0.12722 1 0.60638 1