Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.038	0.223	0.424	4.0	-0.656	81.0	85.0
IHH	0.017	0.081	0.269	25.0	-0.237	9.0	34.0
SHH Np/Cholesterol/GAS1	-0.001	0.081	-9999.0	0.0	-0.35	39.0	39.0
LRPAP1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.001	0.08	0.348	39.0	-9999.0	0.0	39.0
SMO/beta Arrestin2	-0.015	0.204	-9999.0	0.0	-0.631	67.0	67.0
SMO	-0.039	0.206	-9999.0	0.0	-0.657	69.0	69.0
AKT1	0.0	0.123	-9999.0	0.0	-0.576	16.0	16.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.02	0.16	-9999.0	0.0	-0.6	58.0	58.0
ADRBK1	0.023	0.007	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.038	0.202	-9999.0	0.0	-0.643	69.0	69.0
STIL	0.012	0.174	0.301	26.0	-0.494	62.0	88.0
DHH N/PTCH2	-0.018	0.156	-9999.0	0.0	-0.465	86.0	86.0
DHH N/PTCH1	-0.024	0.201	0.292	1.0	-0.515	102.0	103.0
PIK3CA	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.101	0.265	1.0	-0.6	22.0	23.0
PTHLH	-0.056	0.291	0.57	1.0	-0.845	84.0	85.0
determination of left/right symmetry	-0.038	0.202	-9999.0	0.0	-0.643	69.0	69.0
PIK3R1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.055	0.286	0.569	1.0	-0.832	84.0	85.0
IHH N/Hhip	0.029	0.057	0.362	1.0	-0.488	1.0	2.0
DHH N/Hhip	0.023	0.081	-9999.0	0.0	-0.44	23.0	23.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.038	0.202	-9999.0	0.0	-0.643	69.0	69.0
pancreas development	0.024	0.033	0.264	8.0	-0.599	1.0	9.0
HHAT	0.02	0.023	-9999.0	0.0	-0.6	1.0	1.0
PI3K	0.033	0.01	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.009	0.14	-9999.0	0.0	-0.6	44.0	44.0
somite specification	-0.038	0.202	-9999.0	0.0	-0.643	69.0	69.0
SHH Np/Cholesterol/PTCH1	-0.022	0.159	0.283	2.0	-0.51	65.0	67.0
SHH Np/Cholesterol/PTCH2	-0.011	0.097	-9999.0	0.0	-0.353	56.0	56.0
SHH Np/Cholesterol/Megalin	-0.064	0.156	0.283	3.0	-0.354	170.0	173.0
SHH	-0.001	0.037	0.355	4.0	-0.451	1.0	5.0
catabolic process	-0.028	0.202	0.351	1.0	-0.574	87.0	88.0
SMO/Vitamin D3	-0.005	0.196	0.368	11.0	-0.582	64.0	75.0
SHH Np/Cholesterol/Hhip	0.016	0.034	0.281	6.0	-0.358	2.0	8.0
LRP2	-0.126	0.276	0.265	20.0	-0.6	206.0	226.0
receptor-mediated endocytosis	-0.078	0.222	0.306	7.0	-0.616	79.0	86.0
SHH Np/Cholesterol/BOC	-0.006	0.091	-9999.0	0.0	-0.352	49.0	49.0
SHH Np/Cholesterol/CDO	0.013	0.043	-9999.0	0.0	-0.355	9.0	9.0
mesenchymal cell differentiation	-0.016	0.034	0.356	2.0	-0.278	6.0	8.0
mol:Vitamin D3	0.006	0.181	0.346	16.0	-0.512	65.0	81.0
IHH N/PTCH2	-0.014	0.154	-9999.0	0.0	-0.497	69.0	69.0
CDON	0.015	0.065	-9999.0	0.0	-0.6	9.0	9.0
IHH N/PTCH1	-0.019	0.208	0.356	3.0	-0.578	87.0	90.0
Megalin/LRPAP1	-0.083	0.212	-9999.0	0.0	-0.443	209.0	209.0
PTCH2	-0.028	0.173	-9999.0	0.0	-0.6	69.0	69.0
SHH Np/Cholesterol	0.01	0.016	-9999.0	0.0	-0.354	1.0	1.0
PTCH1	-0.028	0.202	0.351	1.0	-0.576	87.0	88.0
HHIP	0.024	0.033	0.265	8.0	-0.6	1.0	9.0