Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.067 0.209 0.316 1.0 -0.539 50.0 51.0 MAP3K8 0.009 0.047 -9999.0 0.0 -0.605 4.0 4.0 FOS -0.026 0.146 0.32 2.0 -0.462 37.0 39.0 PRKCA -0.004 0.093 0.244 2.0 -0.607 18.0 20.0 PTPN7 0.019 0.06 0.252 43.0 -9999.0 0.0 43.0 HRAS 0.023 0.01 0.265 1.0 -9999.0 0.0 1.0 PRKCB 0.004 0.081 0.258 13.0 -0.606 11.0 24.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.022 0.035 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.005 0.095 -9999.0 0.0 -0.806 5.0 5.0 MAP2K1 -0.014 0.122 -9999.0 0.0 -0.529 32.0 32.0 ELK1 0.005 0.03 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.015 0.105 -9999.0 0.0 -0.511 30.0 30.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 267.0 267.0 MAPK1 -0.011 0.121 -9999.0 0.0 -0.46 31.0 31.0 RAF1 -0.014 0.104 -9999.0 0.0 -0.506 30.0 30.0 KRAS 0.022 0.006 -9999.0 0.0 -9999.0 0.0 0.0