Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.046	0.236	0.585	2.0	-0.556	73.0	75.0
IHH	0.021	0.075	-9999.0	0.0	-0.198	1.0	1.0
SHH Np/Cholesterol/GAS1	-0.067	0.147	-9999.0	0.0	-0.314	124.0	124.0
LRPAP1	0.033	0.007	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.067	0.146	0.312	124.0	-9999.0	0.0	124.0
SMO/beta Arrestin2	-0.003	0.187	0.409	2.0	-0.478	30.0	32.0
SMO	-0.017	0.185	0.441	2.0	-0.495	31.0	33.0
AKT1	-0.02	0.19	0.305	1.0	-0.578	38.0	39.0
ARRB2	0.031	0.01	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.09	0.236	-9999.0	0.0	-0.543	108.0	108.0
ADRBK1	0.031	0.01	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
STIL	0.041	0.15	0.338	32.0	-0.341	7.0	39.0
DHH N/PTCH2	0.049	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.005	0.163	0.376	2.0	-0.324	82.0	84.0
PIK3CA	0.032	0.008	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.034	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PTHLH	-0.113	0.393	0.518	6.0	-0.899	94.0	100.0
determination of left/right symmetry	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
PIK3R1	-0.019	0.164	-9999.0	0.0	-0.543	45.0	45.0
skeletal system development	-0.11	0.388	0.518	6.0	-0.887	94.0	100.0
IHH N/Hhip	0.038	0.053	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/Hhip	0.05	0.012	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
pancreas development	0.034	0.012	-9999.0	0.0	-9999.0	0.0	0.0
HHAT	0.023	0.06	-9999.0	0.0	-0.543	5.0	5.0
PI3K	0.006	0.125	-9999.0	0.0	-0.38	46.0	46.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.143	0.266	-9999.0	0.0	-0.543	155.0	155.0
somite specification	-0.016	0.183	0.44	2.0	-0.488	31.0	33.0
SHH Np/Cholesterol/PTCH1	-0.01	0.122	-9999.0	0.0	-0.326	15.0	15.0
SHH Np/Cholesterol/PTCH2	0.024	0.037	-9999.0	0.0	-0.312	5.0	5.0
SHH Np/Cholesterol/Megalin	-0.057	0.145	-9999.0	0.0	-0.32	110.0	110.0
SHH	0.01	0.043	-9999.0	0.0	-0.4	5.0	5.0
catabolic process	-0.01	0.176	0.462	2.0	-0.358	86.0	88.0
SMO/Vitamin D3	0.009	0.172	0.405	16.0	-0.442	14.0	30.0
SHH Np/Cholesterol/Hhip	0.024	0.038	-9999.0	0.0	-0.312	5.0	5.0
LRP2	-0.121	0.256	-9999.0	0.0	-0.543	136.0	136.0
receptor-mediated endocytosis	-0.063	0.196	0.347	9.0	-0.504	39.0	48.0
SHH Np/Cholesterol/BOC	-0.037	0.129	-9999.0	0.0	-0.312	84.0	84.0
SHH Np/Cholesterol/CDO	0.018	0.051	-9999.0	0.0	-0.346	8.0	8.0
mesenchymal cell differentiation	-0.024	0.038	0.31	5.0	-9999.0	0.0	5.0
mol:Vitamin D3	0.027	0.159	0.41	17.0	-0.338	13.0	30.0
IHH N/PTCH2	0.037	0.052	-9999.0	0.0	-9999.0	0.0	0.0
CDON	0.026	0.052	-9999.0	0.0	-0.543	4.0	4.0
IHH N/PTCH1	-0.002	0.18	0.463	2.0	-0.36	86.0	88.0
Megalin/LRPAP1	-0.073	0.199	-9999.0	0.0	-0.399	136.0	136.0
PTCH2	0.034	0.005	-9999.0	0.0	-9999.0	0.0	0.0
SHH Np/Cholesterol	0.014	0.034	-9999.0	0.0	-0.31	5.0	5.0
PTCH1	-0.01	0.176	0.463	2.0	-0.359	86.0	88.0
HHIP	0.034	0.012	-9999.0	0.0	-9999.0	0.0	0.0