Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.093 0.2 0.447 22.0 -9999.0 0.0 22.0 KIRREL -0.089 0.229 -9999.0 0.0 -0.62 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.093 0.201 -9999.0 0.0 -0.448 22.0 22.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.075 0.145 -9999.0 0.0 -0.394 12.0 12.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.034 0.119 -9999.0 0.0 -0.317 12.0 12.0 FYN -0.061 0.144 -9999.0 0.0 -0.374 12.0 12.0 mol:Ca2+ -0.074 0.143 -9999.0 0.0 -0.391 12.0 12.0 mol:DAG -0.075 0.144 -9999.0 0.0 -0.393 12.0 12.0 NPHS2 -0.011 0.025 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.075 0.144 -9999.0 0.0 -0.393 12.0 12.0 regulation of endocytosis -0.051 0.136 -9999.0 0.0 -0.347 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.076 0.148 -9999.0 0.0 -0.402 12.0 12.0 establishment of cell polarity -0.093 0.2 -9999.0 0.0 -0.447 22.0 22.0 Nephrin/NEPH1/podocin/NCK1-2 -0.047 0.141 -9999.0 0.0 -0.378 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.051 0.138 -9999.0 0.0 -0.351 12.0 12.0 NPHS1 -0.05 0.15 -9999.0 0.0 -0.515 9.0 9.0 Nephrin/NEPH1/podocin -0.062 0.144 -9999.0 0.0 -0.376 12.0 12.0 TJP1 0.006 0.066 -9999.0 0.0 -0.639 1.0 1.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.075 0.145 -9999.0 0.0 -0.394 12.0 12.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.075 0.145 -9999.0 0.0 -0.394 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.08 0.16 -9999.0 0.0 -0.376 15.0 15.0 cytoskeleton organization -0.04 0.142 -9999.0 0.0 -0.372 12.0 12.0 Nephrin/NEPH1 -0.065 0.147 -9999.0 0.0 -0.322 22.0 22.0 Nephrin/NEPH1/ZO-1 -0.085 0.16 -9999.0 0.0 -0.357 23.0 23.0