Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.04 0.16 0.431 12.0 -9999.0 0.0 12.0 KIRREL -0.061 0.204 -9999.0 0.0 -0.503 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.04 0.161 -9999.0 0.0 -0.432 12.0 12.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.011 0.133 -9999.0 0.0 -0.346 11.0 11.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.028 0.098 -9999.0 0.0 -0.284 11.0 11.0 FYN -0.025 0.135 0.252 6.0 -0.323 11.0 17.0 mol:Ca2+ -0.007 0.129 -9999.0 0.0 -0.344 10.0 10.0 mol:DAG -0.006 0.13 -9999.0 0.0 -0.345 10.0 10.0 NPHS2 -0.021 0.029 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.006 0.13 -9999.0 0.0 -0.345 10.0 10.0 regulation of endocytosis -0.015 0.117 -9999.0 0.0 -0.306 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.128 -9999.0 0.0 -0.343 11.0 11.0 establishment of cell polarity -0.04 0.16 -9999.0 0.0 -0.431 12.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 -0.01 0.126 -9999.0 0.0 -0.319 11.0 11.0 Nephrin/NEPH1/beta Arrestin2 -0.014 0.119 -9999.0 0.0 -0.31 11.0 11.0 NPHS1 -0.021 0.066 -9999.0 0.0 -0.226 6.0 6.0 Nephrin/NEPH1/podocin -0.018 0.121 -9999.0 0.0 -0.325 11.0 11.0 TJP1 0.022 0.062 -9999.0 0.0 -0.571 1.0 1.0 NCK1 0.021 0.013 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.005 0.131 -9999.0 0.0 -0.347 10.0 10.0 CD2AP 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.01 0.135 -9999.0 0.0 -0.346 11.0 11.0 GRB2 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.038 0.141 0.269 5.0 -0.325 13.0 18.0 cytoskeleton organization -0.038 0.118 -9999.0 0.0 -0.34 11.0 11.0 Nephrin/NEPH1 -0.024 0.116 -9999.0 0.0 -0.323 11.0 11.0 Nephrin/NEPH1/ZO-1 -0.022 0.143 -9999.0 0.0 -0.369 12.0 12.0