Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 0.019 0.046 -9999.0 0.0 -0.509 1.0 1.0 EPHB2 0.022 0.061 -9999.0 0.0 -0.383 3.0 3.0 EFNB1 0.013 0.039 -9999.0 0.0 -0.22 4.0 4.0 mol:GTP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.003 0.108 -9999.0 0.0 -0.274 3.0 3.0 Ephrin B2/EPHB1-2 -0.015 0.091 -9999.0 0.0 -0.288 2.0 2.0 neuron projection morphogenesis -0.015 0.093 -9999.0 0.0 -0.263 3.0 3.0 Ephrin B1/EPHB1-2/Tiam1 -0.014 0.114 -9999.0 0.0 -0.284 5.0 5.0 DNM1 0.024 0.057 -9999.0 0.0 -0.319 4.0 4.0 cell-cell signaling -0.001 0.005 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 -0.013 0.073 -9999.0 0.0 -0.42 4.0 4.0 YES1 -0.03 0.123 -9999.0 0.0 -0.684 4.0 4.0 Ephrin B1/EPHB1-2/NCK2 -0.013 0.115 -9999.0 0.0 -0.287 5.0 5.0 PI3K 0.02 0.088 -9999.0 0.0 -0.375 5.0 5.0 mol:GDP -0.015 0.112 -9999.0 0.0 -0.282 5.0 5.0 ITGA2B 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 endothelial cell proliferation -0.005 0.08 -9999.0 0.0 -0.185 23.0 23.0 FYN -0.02 0.123 -9999.0 0.0 -0.654 5.0 5.0 MAP3K7 -0.019 0.076 -9999.0 0.0 -0.451 4.0 4.0 FGR -0.014 0.098 -9999.0 0.0 -0.65 3.0 3.0 TIAM1 0.032 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PIK3R1 0.033 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RGS3 0.033 0.004 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion 0.014 0.076 -9999.0 0.0 -0.373 3.0 3.0 LYN -0.016 0.113 -9999.0 0.0 -0.66 4.0 4.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.017 0.1 -9999.0 0.0 -0.594 4.0 4.0 Ephrin B1/EPHB1-2 -0.017 0.065 -9999.0 0.0 -0.532 2.0 2.0 SRC -0.017 0.106 -9999.0 0.0 -0.631 4.0 4.0 ITGB3 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 EPHB1 -0.084 0.165 -9999.0 0.0 -0.315 50.0 50.0 EPHB4 -0.037 0.138 -9999.0 0.0 -0.317 29.0 29.0 RAC1 0.03 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 -0.005 0.081 -9999.0 0.0 -0.185 23.0 23.0 alphaIIb/beta3 Integrin 0.048 0.01 -9999.0 0.0 -9999.0 0.0 0.0 BLK -0.042 0.115 -9999.0 0.0 -0.699 3.0 3.0 HCK -0.017 0.09 -9999.0 0.0 -0.696 2.0 2.0 regulation of stress fiber formation 0.014 0.113 0.285 5.0 -9999.0 0.0 5.0 MAPK8 -0.011 0.07 -9999.0 0.0 -0.429 3.0 3.0 Ephrin B1/EPHB1-2/RGS3 -0.014 0.114 -9999.0 0.0 -0.287 5.0 5.0 endothelial cell migration 0.013 0.14 0.384 5.0 -0.473 3.0 8.0 NCK2 0.034 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 -0.075 0.158 -9999.0 0.0 -0.302 46.0 46.0 regulation of focal adhesion formation 0.014 0.113 0.285 5.0 -9999.0 0.0 5.0 chemotaxis 0.015 0.113 0.285 5.0 -9999.0 0.0 5.0 PIK3CA 0.033 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GTP -0.009 0.101 -9999.0 0.0 -0.268 3.0 3.0 angiogenesis -0.017 0.065 -9999.0 0.0 -0.529 2.0 2.0 LCK -0.018 0.111 -9999.0 0.0 -0.656 4.0 4.0