Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.024 0.106 0.317 30.0 -9999.0 0.0 30.0 KIRREL -0.011 0.095 -9999.0 0.0 -0.464 11.0 11.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.024 0.106 -9999.0 0.0 -0.318 30.0 30.0 PLCG1 0.009 0.041 -9999.0 0.0 -0.459 2.0 2.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.035 0.127 -9999.0 0.0 -0.33 31.0 31.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.0 0.072 -9999.0 0.0 -0.328 4.0 4.0 FYN -0.017 0.085 -9999.0 0.0 -0.292 10.0 10.0 mol:Ca2+ -0.013 0.096 -9999.0 0.0 -0.343 10.0 10.0 mol:DAG -0.013 0.096 -9999.0 0.0 -0.345 10.0 10.0 NPHS2 -0.014 0.079 -9999.0 0.0 -0.452 8.0 8.0 mol:IP3 -0.013 0.096 -9999.0 0.0 -0.345 10.0 10.0 regulation of endocytosis -0.007 0.081 -9999.0 0.0 -0.353 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.089 -9999.0 0.0 -0.238 35.0 35.0 establishment of cell polarity -0.024 0.106 -9999.0 0.0 -0.317 30.0 30.0 Nephrin/NEPH1/podocin/NCK1-2 -0.005 0.089 -9999.0 0.0 -0.371 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.006 0.082 -9999.0 0.0 -0.357 4.0 4.0 NPHS1 -0.025 0.117 -9999.0 0.0 -0.444 19.0 19.0 Nephrin/NEPH1/podocin -0.016 0.086 -9999.0 0.0 -0.293 10.0 10.0 TJP1 0.01 0.03 -9999.0 0.0 -0.476 1.0 1.0 NCK1 0.008 0.042 -9999.0 0.0 -0.476 2.0 2.0 NCK2 0.01 0.03 -9999.0 0.0 -0.476 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.013 0.097 -9999.0 0.0 -0.346 10.0 10.0 CD2AP -0.029 0.135 -9999.0 0.0 -0.476 22.0 22.0 Nephrin/NEPH1/podocin/GRB2 -0.011 0.09 -9999.0 0.0 -0.306 9.0 9.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.023 0.099 -9999.0 0.0 -0.304 16.0 16.0 cytoskeleton organization 0.001 0.079 -9999.0 0.0 -0.356 4.0 4.0 Nephrin/NEPH1 -0.014 0.074 -9999.0 0.0 -0.218 30.0 30.0 Nephrin/NEPH1/ZO-1 -0.01 0.089 -9999.0 0.0 -0.251 30.0 30.0