Clinical Features	Time to Death		AGE		GENDER		PATHOLOGY.T		PATHOLOGY.N		TUMOR.STAGE		RADIATIONS.RADIATION.REGIMENINDICATION		NUMBERPACKYEARSSMOKED		STOPPEDSMOKINGYEAR		TOBACCOSMOKINGHISTORYINDICATOR		YEAROFTOBACCOSMOKINGONSET	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	t-test_P	t-test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	t-test_P	t-test_Q
NOTCH1	57 (19%)	249	0.59513	1	0.12886	1	0.3233	1	0.75275	1	0.86569	1	0.94759	1	0.50059	1	0.0087165	1	0.45916	1	0.5877	1	0.81324	1
CDKN2A	65 (21%)	241	0.45948	1	0.69667	1	0.63989	1	0.6643	1	0.97978	1	0.26352	1	0.10787	1	0.070868	1	0.25861	1	0.1829	1	0.39371	1
HRAS	10 (3%)	296	0.079092	1	0.22718	1	1	1	0.24136	1	0.053819	1	0.088509	1	0.46135	1	0.15665	1	0.92409	1	0.15689	1	0.21651	1
NFE2L2	17 (6%)	289	0.037997	1	0.006976	1	0.57581	1	0.772	1	0.88426	1	0.50247	1	0.25552	1	0.90557	1	0.63563	1	0.42575	1	0.30925	1
PIK3CA	64 (21%)	242	0.27151	1	0.83191	1	0.2071	1	0.74154	1	0.47745	1	0.39285	1	1	1	0.71508	1	0.35386	1	0.69915	1	0.89774	1
TP53	214 (70%)	92	1.5908e-05	0.0155	0.76941	1	0.57805	1	0.0057709	1	0.017471	1	0.0067002	1	0.15224	1	0.10901	1	0.4237	1	0.38659	1	0.78309	1
CASP8	27 (9%)	279	0.54927	1	0.00030258	0.295	0.0012748	1	0.55929	1	0.10271	1	0.16834	1	0.4912	1	0.22274	1	0.078913	1	0.011375	1	0.13112	1
FAT1	72 (24%)	234	0.7937	1	0.00051048	0.496	0.13132	1	0.5369	1	0.76007	1	0.49866	1	0.87747	1	0.53024	1	0.11994	1	0.024479	1	0.13281	1
JUB	18 (6%)	288	0.094292	1	0.080219	1	1	1	0.45514	1	0.2817	1	0.6399	1	0.78481	1	0.53793	1	0.71468	1	0.18554	1	0.06555	1
MLL2	56 (18%)	250	0.92789	1	0.99327	1	0.86888	1	0.24243	1	0.88147	1	0.40486	1	1	1	0.31551	1	0.048115	1	0.16523	1	0.39345	1
FBXW7	15 (5%)	291	0.89755	1	0.095829	1	0.37184	1	0.63464	1	0.30953	1	0.66822	1	0.54363	1	0.41524	1	0.334	1	0.38632	1	0.37256	1
NSD1	33 (11%)	273	0.19403	1	0.081895	1	0.30097	1	0.77834	1	0.00056152	0.545	0.036194	1	0.3993	1	0.21826	1	0.8425	1	0.29684	1	0.94651	1
BAGE2	11 (4%)	295	0.058947	1	0.25996	1	0.73325	1	0.67784	1	0.80709	1	0.60937	1	0.73548	1	0.96567	1	0.36892	1	0.64547	1	0.72795	1
POTEC	15 (5%)	291	0.22889	1	0.049128	1	0.13292	1	0.2122	1	0.9255	1	0.63591	1	0.54363	1	0.23211	1	3.4601e-05	0.0338	0.0081927	1	0.8718	1
ZNF750	13 (4%)	293	0.57101	1	0.84527	1	0.12301	1	0.059409	1	0.74528	1	0.6698	1	0.52722	1	0.90015	1	0.7266	1	0.43086	1	0.16156	1
EP300	25 (8%)	281	0.64244	1	0.53598	1	0.64122	1	0.95093	1	0.58649	1	0.54883	1	0.63578	1	0.11317	1	0.17022	1	0.37399	1	0.72971	1
POM121L12	14 (5%)	292	0.64875	1	0.91238	1	1	1	0.07357	1	0.34277	1	0.44409	1	0.7588	1	0.42692	1	0.88481	1	0.24458	1	0.77272	1
RHOA	4 (1%)	302	0.2882	1	0.91598	1	0.30318	1	0.22387	1	0.18218	1	0.60019	1	0.57549	1	0.0018613	1	NA	NA	0.16894	1	0.54669	1
B2M	7 (2%)	299	0.2326	1	0.48302	1	1	1	0.60968	1	NA	NA	0.78979	1	0.68284	1	NA	NA	NA	NA	0.010966	1	NA	NA
RAC1	9 (3%)	297	0.67617	1	0.0068215	1	0.067629	1	0.41172	1	0.21456	1	0.29721	1	1	1	0.72145	1	0.30294	1	0.27885	1	0.0048066	1
ZNF804B	21 (7%)	285	0.35618	1	0.053971	1	0.8046	1	0.95195	1	0.74301	1	0.66188	1	0.11728	1	0.026572	1	0.022143	1	0.33625	1	0.87306	1
KCNT2	17 (6%)	289	0.40949	1	0.6631	1	0.78689	1	0.23788	1	0.81747	1	0.81566	1	0.25552	1	0.17024	1	0.15307	1	0.080359	1	0.10732	1
RASA1	14 (5%)	292	0.4657	1	0.78313	1	0.36448	1	0.52145	1	0.89477	1	0.84348	1	0.20423	1	0.96823	1	0.84681	1	0.85501	1	0.43746	1
PRIM2	9 (3%)	297	0.65172	1	0.51617	1	1	1	0.46147	1	0.22928	1	0.3418	1	0.45661	1	0.11612	1	0.36892	1	0.0677	1	0.90652	1
CDH10	23 (8%)	283	0.17054	1	0.036212	1	0.33573	1	0.11313	1	0.79725	1	0.070148	1	0.21412	1	0.098	1	0.072206	1	0.8282	1	0.15329	1
CNTNAP5	15 (5%)	291	0.17279	1	0.58857	1	0.076936	1	0.029148	1	0.37884	1	0.049217	1	0.76768	1	0.13881	1	0.012765	1	0.17256	1	0.23422	1
POTEG	10 (3%)	296	0.43195	1	0.078876	1	1	1	0.47743	1	0.89025	1	0.095884	1	0.71902	1	0.31002	1	NA	NA	0.4463	1	0.018662	1
ZNF99	22 (7%)	284	0.28399	1	0.87562	1	0.1449	1	0.12364	1	0.71709	1	0.43251	1	0.80344	1	0.32683	1	0.00070825	0.686	0.19647	1	0.62347	1
OR2T12	11 (4%)	295	0.8757	1	0.051615	1	1	1	0.03252	1	0.13366	1	0.005287	1	0.30069	1	0.037937	1	0.11193	1	0.059833	1	0.20051	1
REG1A	8 (3%)	298	0.45823	1	0.57281	1	1	1	0.63616	1	1	1	1	1	0.42481	1	0.1364	1	0.059994	1	0.23554	1	0.58051	1
PABPC5	9 (3%)	297	0.72314	1	0.71745	1	1	1	0.2138	1	0.68586	1	0.19873	1	0.69792	1	0.2936	1	NA	NA	0.31986	1	0.17439	1
IL32	4 (1%)	302	0.12658	1	0.93188	1	0.30318	1	0.87804	1	0.087478	1	0.46382	1	0.57549	1	NA	NA	NA	NA	0.65103	1	NA	NA
PRAMEF11	10 (3%)	296	0.28885	1	0.040221	1	0.14455	1	0.71046	1	0.68586	1	1	1	0.71902	1	0.11007	1	0.67818	1	0.87205	1	0.097552	1
EPHA2	14 (5%)	292	0.019484	1	0.89069	1	0.22052	1	0.93162	1	0.18379	1	0.8051	1	1	1	0.0074732	1	0.52303	1	0.34896	1	0.079307	1
FCRL4	13 (4%)	293	0.36788	1	0.22332	1	0.52597	1	0.25448	1	0.55539	1	0.48064	1	1	1	0.10911	1	0.15057	1	0.71145	1	0.088287	1
LCP1	12 (4%)	294	0.65365	1	0.84675	1	0.52226	1	0.03085	1	1	1	0.03944	1	0.50959	1	0.91474	1	0.22189	1	0.45658	1	0.70001	1
LRFN5	13 (4%)	293	0.89295	1	0.86182	1	1	1	0.62747	1	0.037716	1	0.87805	1	1	1	0.71858	1	0.43672	1	0.065493	1	0.45717	1
MAPK1	4 (1%)	302	0.45169	1	0.29173	1	1	1	0.51374	1	0.68235	1	0.71209	1	0.57549	1	NA	NA	NA	NA	0.88476	1	NA	NA
PEG3	23 (8%)	283	0.56284	1	0.98263	1	0.46674	1	0.9562	1	0.64241	1	0.71795	1	0.32062	1	0.13989	1	0.0248	1	0.075951	1	0.80128	1
PRSS1	8 (3%)	298	0.2874	1	0.75115	1	0.00060345	0.585	0.86887	1	0.12454	1	1	1	0.20984	1	NA	NA	0.11	1	0.048687	1	0.66978	1
DOK6	8 (3%)	298	0.69529	1	0.34775	1	0.006339	1	0.83518	1	0.12454	1	0.4967	1	0.68461	1	0.074408	1	NA	NA	0.021854	1	0.82189	1
GABRB3	11 (4%)	295	0.12837	1	0.62086	1	0.038938	1	0.28352	1	0.089034	1	0.24725	1	0.73548	1	0.23771	1	0.68088	1	0.97295	1	0.00026578	0.259
STEAP4	10 (3%)	296	0.63372	1	0.98136	1	0.29502	1	0.12984	1	1	1	0.39214	1	1	1	0.038047	1	0.083972	1	0.80771	1	0.36319	1
ASXL3	21 (7%)	285	0.49393	1	0.57176	1	0.45558	1	0.72694	1	0.45947	1	0.47341	1	0.3026	1	0.66925	1	0.62525	1	0.28851	1	0.60934	1
NTM	7 (2%)	299	0.84717	1	0.86954	1	1	1	0.55966	1	1	1	0.097959	1	0.19733	1	0.82294	1	0.62797	1	0.17257	1	0.72136	1
FAM155A	11 (4%)	295	0.66714	1	0.4968	1	0.3002	1	0.50219	1	0.26922	1	0.20226	1	0.48023	1	0.45509	1	0.067628	1	0.19757	1	0.45374	1
HLA-A	9 (3%)	297	0.49821	1	0.26211	1	1	1	0.62005	1	0.33646	1	0.27403	1	0.23986	1	0.7093	1	0.1718	1	0.0055426	1	0.27298	1
KRTAP1-5	3 (1%)	303	0.25778	1	0.52788	1	0.56424	1	NA	NA	NA	NA	NA	NA	0.57314	1	NA	NA	NA	NA	0.47493	1	NA	NA
CTCF	11 (4%)	295	0.23939	1	0.044362	1	0.1811	1	0.93475	1	0.60641	1	0.53279	1	1	1	0.15042	1	0.8532	1	0.031862	1	0.19171	1
BRWD3	16 (5%)	290	0.22189	1	0.68295	1	0.00048595	0.472	0.73105	1	0.38641	1	0.93046	1	0.76901	1	0.83812	1	0.58699	1	0.90038	1	0.98873	1
CNPY3	3 (1%)	303	NA	NA	0.080726	1	0.56424	1	0.84023	1	0.77343	1	1	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
FAM101A	4 (1%)	302	0.80601	1	0.93659	1	1	1	0.60968	1	1	1	0.78979	1	1	1	NA	NA	NA	NA	0.33033	1	NA	NA
HLA-B	9 (3%)	297	0.63605	1	0.70123	1	0.067629	1	0.91305	1	0.025704	1	0.31114	1	0.11813	1	0.82768	1	0.50422	1	0.092197	1	0.082867	1
PSG8	9 (3%)	297	0.98297	1	0.074034	1	0.12083	1	0.95609	1	0.25138	1	0.38226	1	1	1	0.022266	1	0.44952	1	0.92802	1	0.90858	1
OR56A1	8 (3%)	298	0.86577	1	0.88242	1	0.68858	1	0.12984	1	0.89025	1	0.39214	1	1	1	0.27073	1	0.64693	1	0.27382	1	0.91712	1
OR2M2	8 (3%)	298	0.63349	1	0.38393	1	1	1	0.52116	1	0.38938	1	0.55373	1	1	1	0.047927	1	1.1946e-07	0.000117	0.38862	1	0.80147	1
OR4M2	8 (3%)	298	0.37541	1	0.60836	1	0.68858	1	0.43755	1	1	1	0.73777	1	0.68461	1	0.38326	1	NA	NA	0.74067	1	0.97904	1
CPXCR1	7 (2%)	299	0.53451	1	0.48094	1	1	1	0.72492	1	0.80709	1	0.67092	1	0.072842	1	NA	NA	NA	NA	0.2764	1	NA	NA
EYA1	10 (3%)	296	0.8107	1	0.21524	1	0.14455	1	0.10703	1	0.40776	1	0.92737	1	0.71902	1	0.1488	1	0.98217	1	0.96986	1	0.43204	1
LINGO2	10 (3%)	296	0.41214	1	0.30784	1	0.29502	1	0.26294	1	1	1	0.55373	1	0.13062	1	0.79296	1	0.9815	1	0.62981	1	0.72876	1
SEMA5A	19 (6%)	287	0.63633	1	0.3863	1	0.60636	1	0.93162	1	0.24768	1	0.73729	1	1	1	0.037021	1	0.0081326	1	0.031832	1	0.55863	1
TGFBR2	10 (3%)	296	0.6681	1	0.029202	1	1	1	0.71046	1	0.33646	1	0.83326	1	0.069956	1	0.28736	1	0.32895	1	0.33141	1	0.0083921	1
PLSCR1	5 (2%)	301	0.066892	1	0.39542	1	1	1	0.83411	1	0.36168	1	0.76484	1	1	1	NA	NA	NA	NA	0.81654	1	0.30376	1
LIN28B	6 (2%)	300	0.46553	1	0.92849	1	0.35132	1	1	1	NA	NA	0.42708	1	0.64695	1	0.5853	1	NA	NA	0.67135	1	0.63507	1
AGTR1	8 (3%)	298	0.32363	1	0.022443	1	0.45323	1	0.89767	1	0.40776	1	0.67092	1	0.68461	1	0.086622	1	0.019907	1	0.38862	1	0.032914	1
C6	12 (4%)	294	0.72749	1	0.51617	1	0.3212	1	0.84816	1	1	1	0.81706	1	0.50959	1	0.17241	1	0.29859	1	0.87657	1	0.20964	1
MS4A14	9 (3%)	297	0.9982	1	0.40671	1	0.067629	1	0.38217	1	0.4981	1	0.36424	1	0.45661	1	0.79526	1	0.79319	1	0.62409	1	0.81496	1
HIST1H4E	5 (2%)	301	0.85073	1	0.54852	1	0.6176	1	0.87804	1	1	1	0.46382	1	0.33407	1	NA	NA	NA	NA	0.72476	1	NA	NA
LBP	7 (2%)	299	0.97961	1	0.43591	1	0.67818	1	0.84023	1	0.25469	1	1	1	1	1	0.78999	1	NA	NA	0.15245	1	0.82806	1
RGS17	5 (2%)	301	0.52894	1	0.48327	1	0.6176	1	0.84023	1	NA	NA	0.78979	1	0.33407	1	0.94589	1	NA	NA	0.64411	1	NA	NA
LILRB1	12 (4%)	294	0.88488	1	0.90656	1	0.52226	1	0.29216	1	0.52023	1	0.63761	1	1	1	0.1181	1	0.86893	1	0.60239	1	0.57015	1
MAGEL2	12 (4%)	294	0.47723	1	0.34204	1	1	1	0.24001	1	0.099651	1	0.053349	1	0.30783	1	0.41747	1	0.48645	1	0.22522	1	0.55446	1
OR8D4	6 (2%)	300	0.2235	1	0.1317	1	0.19339	1	0.76249	1	0.42809	1	0.19965	1	1	1	0.80356	1	0.07643	1	0.23683	1	0.26317	1
HIST1H1B	7 (2%)	299	0.20436	1	0.085667	1	0.39772	1	0.89767	1	0.14998	1	0.90813	1	0.68284	1	NA	NA	NA	NA	0.055408	1	NA	NA
C3ORF59	8 (3%)	298	0.88689	1	0.83106	1	0.68858	1	0.55418	1	0.12181	1	0.72263	1	1	1	0.37904	1	0.83211	1	0.53719	1	0.42896	1
C8ORF34	7 (2%)	299	0.22333	1	0.40376	1	0.67818	1	0.8529	1	0.88731	1	0.39214	1	0.37667	1	0.32836	1	0.28902	1	0.44332	1	0.039568	1
OR8J1	9 (3%)	297	0.70628	1	0.32049	1	0.45271	1	1	1	0.68586	1	0.92737	1	0.23986	1	0.016566	1	0.00042848	0.417	0.37354	1	0.42564	1
RAB32	3 (1%)	303	0.96967	1	0.35198	1	0.56424	1	1	1	NA	NA	NA	NA	0.16088	1	NA	NA	NA	NA	0.30108	1	0.38119	1
TMEM195	8 (3%)	298	0.66861	1	0.032296	1	1	1	0.8529	1	1	1	0.62099	1	1	1	0.4958	1	0.041162	1	0.20373	1	0.28009	1
PCDH11X	21 (7%)	285	0.72353	1	0.71593	1	0.0037901	1	0.13447	1	0.79725	1	0.97064	1	0.033953	1	0.12478	1	0.39878	1	0.40269	1	0.5307	1
SLITRK4	12 (4%)	294	0.11464	1	0.04172	1	0.52226	1	0.76685	1	0.37848	1	0.95051	1	0.50959	1	0.21094	1	0.64532	1	0.85942	1	0.56448	1
FRG2B	6 (2%)	300	0.89916	1	0.37759	1	0.050299	1	0.76249	1	0.88731	1	0.55373	1	1	1	0.35732	1	NA	NA	0.22796	1	0.24911	1
OR2L13	7 (2%)	299	0.38213	1	0.39172	1	1	1	0.13696	1	0.32764	1	0.21598	1	0.68284	1	0.65214	1	NA	NA	0.55377	1	0.34123	1
CUL3	10 (3%)	296	0.76958	1	0.46673	1	0.73291	1	0.087536	1	0.55412	1	0.28922	1	0.13062	1	0.52693	1	0.2512	1	0.19546	1	0.19742	1
FOSL2	7 (2%)	299	0.0066202	1	0.76128	1	0.39772	1	0.70561	1	0.68235	1	0.87654	1	1	1	0.41224	1	0.81267	1	0.91107	1	0.98581	1
GPR158	12 (4%)	294	0.76365	1	0.77945	1	0.3212	1	0.45281	1	0.25654	1	0.13693	1	0.73697	1	0.70631	1	NA	NA	0.33288	1	0.35918	1
PTPRT	19 (6%)	287	0.79834	1	0.50872	1	0.60636	1	0.13362	1	0.2944	1	0.25147	1	0.27708	1	0.47092	1	0.12458	1	0.60382	1	0.67057	1
POTEH	7 (2%)	299	0.50198	1	0.077457	1	0.67818	1	0.46384	1	0.033032	1	0.87654	1	1	1	0.80964	1	NA	NA	0.27091	1	0.14129	1
OR5D13	7 (2%)	299	0.28517	1	0.20899	1	0.018318	1	0.65056	1	1	1	0.87654	1	1	1	0.30628	1	0.035341	1	0.57494	1	0.37461	1
PRB1	7 (2%)	299	0.55825	1	0.52816	1	0.19597	1	0.61772	1	0.40776	1	0.53083	1	0.37667	1	0.2603	1	0.014782	1	0.36593	1	0.86774	1
NEUROD6	7 (2%)	299	0.68495	1	0.3258	1	1	1	0.63616	1	1	1	1	1	0.072842	1	0.39423	1	0.89462	1	0.91107	1	0.81016	1
DPP10	16 (5%)	290	0.45306	1	0.11091	1	0.77495	1	0.97301	1	0.76127	1	0.56883	1	0.76901	1	0.88576	1	0.99046	1	0.79779	1	0.052786	1
DPPA4	7 (2%)	299	0.5288	1	0.69172	1	1	1	1	1	0.13823	1	0.73777	1	0.37667	1	0.8489	1	0.91659	1	0.91107	1	0.66111	1
EPDR1	6 (2%)	300	0.94564	1	0.80465	1	0.66766	1	0.58691	1	0.2335	1	0.81024	1	0.64695	1	0.89844	1	NA	NA	0.31992	1	0.16645	1