Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 12 (4%) 310 0.7136 1 0.48566 1 0.22894 1 0.76034 1 0.099958 1 0.22091 1 0.81195 1 0.57293 1 1q gain 41 (13%) 281 0.0068617 1 0.00075519 0.43 0.96627 1 0.23397 1 0.0074847 1 0.0027915 1 0.0069213 1 0.12091 1 2p gain 30 (9%) 292 0.00018769 0.108 0.00021263 0.122 0.7555 1 0.9459 1 0.021879 1 0.036074 1 0.41494 1 0.65356 1 2q gain 20 (6%) 302 0.015243 1 0.0034679 1 0.89844 1 1 1 0.10872 1 0.15713 1 0.83289 1 0.58152 1 3p gain 27 (8%) 295 3.6983e-05 0.0219 3.6601e-05 0.0217 0.67174 1 0.18218 1 0.0015812 0.89 0.001817 1 0.0041422 1 0.08143 1 3q gain 104 (32%) 218 0.00035154 0.201 4.0313e-05 0.0238 0.20102 1 0.13095 1 0.012022 1 0.0017957 1 0.00068051 0.388 0.14852 1 4p gain 13 (4%) 309 0.0039091 1 0.064019 1 0.29199 1 1 1 0.16623 1 0.22798 1 0.34974 1 0.26777 1 4q gain 9 (3%) 313 0.23256 1 0.10256 1 0.29459 1 1 1 0.57619 1 0.63001 1 0.91726 1 0.62426 1 5p gain 82 (25%) 240 2.5361e-08 1.56e-05 0.043708 1 0.62242 1 0.56208 1 0.39944 1 0.4094 1 0.70957 1 0.51257 1 5q gain 28 (9%) 294 0.10617 1 0.69268 1 0.82538 1 0.82835 1 0.81884 1 0.46147 1 0.96811 1 0.26062 1 6p gain 26 (8%) 296 0.065231 1 0.046554 1 0.76206 1 0.49582 1 0.90196 1 0.87117 1 0.9004 1 1 1 6q gain 19 (6%) 303 0.01984 1 0.082072 1 0.45971 1 0.82835 1 0.72713 1 0.37765 1 0.82685 1 0.79045 1 7p gain 72 (22%) 250 1.1217e-06 0.000679 0.00015522 0.0902 0.88988 1 0.87504 1 0.86777 1 0.8952 1 0.48492 1 0.47178 1 7q gain 45 (14%) 277 6.967e-06 0.00417 1.0098e-06 0.000612 0.81 1 0.80532 1 0.27532 1 0.11215 1 0.14301 1 0.18628 1 8p gain 49 (15%) 273 7.8503e-06 0.00469 0.002003 1 0.66963 1 0.18019 1 0.38091 1 0.31331 1 0.28741 1 0.166 1 8q gain 129 (40%) 193 2.2487e-07 0.000137 0.00028003 0.16 0.79781 1 0.43119 1 0.56757 1 0.65111 1 0.56996 1 0.090486 1 9p gain 38 (12%) 284 0.00020261 0.117 0.05949 1 0.3435 1 0.4383 1 0.28772 1 0.64347 1 0.4414 1 0.94625 1 9q gain 47 (15%) 275 4.3282e-06 0.00261 0.010276 1 0.35521 1 0.30102 1 0.38289 1 0.19076 1 0.21962 1 0.52426 1 10p gain 12 (4%) 310 0.50958 1 0.0027806 1 0.18854 1 0.52142 1 0.054985 1 0.068933 1 0.25606 1 0.16159 1 10q gain 6 (2%) 316 0.44526 1 0.33841 1 0.73665 1 0.76833 1 1 1 1 1 0.67341 1 0.74983 1 11p gain 16 (5%) 306 0.0075758 1 0.67008 1 1 1 0.32315 1 0.75433 1 0.8449 1 0.85296 1 0.76469 1 11q gain 16 (5%) 306 0.10323 1 0.40726 1 0.624 1 1 1 0.15852 1 0.2952 1 0.65285 1 1 1 12p gain 61 (19%) 261 1.9712e-07 0.00012 1.8913e-05 0.0113 0.94907 1 0.68811 1 0.0039875 1 0.00061189 0.349 0.00012481 0.0726 0.068729 1 12q gain 25 (8%) 297 0.010694 1 0.002095 1 1 1 0.39646 1 0.039783 1 0.00086857 0.493 0.0038736 1 0.051026 1 13q gain 17 (5%) 305 0.0011721 0.661 0.035201 1 0.17206 1 0.80473 1 0.60305 1 0.90447 1 0.49784 1 0.28939 1 14q gain 52 (16%) 270 9.9599e-08 6.11e-05 0.015916 1 0.19035 1 0.11573 1 0.027051 1 0.027049 1 0.021894 1 0.11312 1 15q gain 13 (4%) 309 0.37003 1 0.27528 1 1 1 0.43313 1 0.72671 1 0.12361 1 0.48943 1 0.38081 1 16p gain 21 (7%) 301 0.0010872 0.614 8.4477e-05 0.0493 0.028593 1 0.12288 1 0.24107 1 0.9576 1 0.70572 1 0.66198 1 16q gain 28 (9%) 294 0.0083137 1 0.0042262 1 0.39093 1 1 1 0.02658 1 0.43686 1 0.60719 1 0.088373 1 17p gain 19 (6%) 303 0.0039607 1 0.082378 1 0.88787 1 0.40819 1 0.17981 1 0.56103 1 0.29451 1 0.38367 1 17q gain 23 (7%) 299 0.15094 1 0.096343 1 0.27522 1 0.49975 1 0.18967 1 0.051935 1 0.25585 1 0.58087 1 18p gain 52 (16%) 270 4.8489e-06 0.00291 0.058147 1 0.90728 1 0.2516 1 0.1137 1 0.0048968 1 0.50388 1 0.4135 1 18q gain 20 (6%) 302 0.00024082 0.138 0.00017731 0.103 0.15748 1 0.32315 1 0.019169 1 0.017071 1 0.009118 1 1 1 19p gain 12 (4%) 310 0.0030572 1 0.0049465 1 0.18435 1 0.096207 1 0.38904 1 0.023114 1 0.19375 1 0.16159 1 19q gain 21 (7%) 301 0.0059141 1 0.058112 1 0.87864 1 0.38127 1 0.15755 1 0.31863 1 0.22679 1 0.38917 1 20p gain 65 (20%) 257 3.1823e-07 0.000194 7.9034e-05 0.0463 0.29599 1 0.14871 1 0.61705 1 0.36452 1 0.53498 1 0.72593 1 20q gain 70 (22%) 252 3.2562e-09 2.03e-06 6.0967e-05 0.0358 0.87566 1 0.75327 1 0.48295 1 0.78852 1 0.98477 1 0.44732 1 21q gain 9 (3%) 313 0.089029 1 0.77263 1 0.68196 1 1 1 0.019285 1 0.055196 1 0.26869 1 0.8047 1 22q gain 39 (12%) 283 0.0066518 1 8.2145e-05 0.0481 0.56935 1 0.41661 1 0.07753 1 0.018974 1 0.25717 1 0.52657 1 Xq gain 21 (7%) 301 0.008975 1 0.10941 1 0.18663 1 0.16223 1 0.33321 1 0.76977 1 1 1 0.82345 1 1p loss 16 (5%) 306 5.1262e-08 3.15e-05 9.7016e-07 0.000589 0.17298 1 0.066231 1 0.012862 1 0.015561 1 0.063529 1 0.33802 1 2p loss 5 (2%) 317 0.692 1 0.011758 1 0.11988 1 1 1 0.054007 1 0.036052 1 0.070817 1 0.21324 1 2q loss 9 (3%) 313 0.57314 1 0.06623 1 0.064353 1 0.42388 1 0.031299 1 0.025751 1 0.10686 1 0.010511 1 3p loss 125 (39%) 197 1.8649e-12 1.17e-09 1.5268e-07 9.34e-05 0.68182 1 0.86096 1 0.35344 1 0.1488 1 0.051785 1 0.47212 1 3q loss 21 (7%) 301 0.066539 1 0.11526 1 0.64243 1 0.45282 1 0.8813 1 0.95942 1 0.17364 1 0.54891 1 4p loss 78 (24%) 244 1.761e-11 1.11e-08 4.5635e-08 2.81e-05 0.32993 1 0.16987 1 0.0045716 1 0.00027455 0.158 0.00016982 0.0985 0.097737 1 4q loss 51 (16%) 271 4.0769e-09 2.54e-06 5.9352e-06 0.00356 0.37799 1 0.24313 1 0.028144 1 0.0052221 1 0.0021317 1 0.03604 1 5p loss 10 (3%) 312 0.0027442 1 0.0036713 1 0.72685 1 1 1 0.28669 1 0.39935 1 0.037119 1 1 1 5q loss 62 (19%) 260 1.6724e-10 1.05e-07 2.3072e-10 1.44e-07 0.048537 1 0.32724 1 0.011121 1 5.518e-05 0.0325 0.0050595 1 0.5499 1 6p loss 19 (6%) 303 0.13454 1 0.012689 1 0.10045 1 0.11617 1 0.031706 1 0.1111 1 0.028568 1 0.10638 1 6q loss 21 (7%) 301 0.23742 1 0.070076 1 0.04742 1 0.052852 1 0.37927 1 0.39162 1 0.10747 1 0.087538 1 7p loss 5 (2%) 317 0.12112 1 0.38838 1 NA NA NA NA 0.3907 1 0.45231 1 0.014001 1 1 1 7q loss 9 (3%) 313 0.045428 1 0.16118 1 1 1 0.74002 1 0.36294 1 0.69365 1 0.087761 1 0.069221 1 8p loss 70 (22%) 252 9.2502e-05 0.0539 1.393e-05 0.0083 0.97581 1 1 1 0.72595 1 0.59037 1 0.1312 1 0.27461 1 8q loss 6 (2%) 316 0.15312 1 0.10459 1 0.63753 1 0.76833 1 1 1 0.51457 1 0.88077 1 1 1 9p loss 89 (28%) 233 9.9474e-09 6.17e-06 1.2443e-08 7.7e-06 0.38419 1 0.94475 1 0.25175 1 0.052937 1 0.0024265 1 0.077005 1 9q loss 31 (10%) 291 0.0084554 1 0.067865 1 0.78518 1 0.49572 1 0.82908 1 0.85521 1 0.70368 1 0.0023315 1 10p loss 47 (15%) 275 0.010709 1 0.071899 1 0.60483 1 0.44611 1 0.85777 1 0.7506 1 0.27001 1 0.3933 1 10q loss 26 (8%) 296 0.011275 1 0.0029624 1 0.89331 1 0.47524 1 0.03058 1 0.0010733 0.607 0.007128 1 0.25762 1 11p loss 41 (13%) 281 0.00089271 0.506 0.04444 1 0.68811 1 0.8071 1 0.0017333 0.974 0.0059758 1 0.039162 1 0.40578 1 11q loss 62 (19%) 260 7.4881e-09 4.65e-06 7.5501e-05 0.0443 0.94514 1 0.58948 1 0.011212 1 0.062164 1 0.3016 1 0.89652 1 12p loss 12 (4%) 310 0.041808 1 0.13896 1 0.33788 1 0.19873 1 0.46806 1 0.45915 1 0.34231 1 0.41046 1 12q loss 8 (2%) 314 0.19719 1 0.073031 1 0.61425 1 0.66597 1 0.20101 1 0.30816 1 0.60454 1 0.010733 1 13q loss 65 (20%) 257 8.9973e-10 5.62e-07 9.4774e-10 5.91e-07 0.85732 1 0.69192 1 0.028593 1 2.3757e-05 0.0141 0.028907 1 0.061314 1 14q loss 16 (5%) 306 0.12069 1 0.041537 1 0.36982 1 0.72626 1 0.010806 1 0.015397 1 0.1439 1 0.33802 1 15q loss 23 (7%) 299 0.10021 1 0.13597 1 0.41995 1 0.15026 1 0.70773 1 0.35953 1 0.32456 1 0.52237 1 16p loss 12 (4%) 310 0.59662 1 0.029407 1 0.07802 1 0.27374 1 0.041388 1 0.013987 1 0.10008 1 0.10571 1 16q loss 26 (8%) 296 0.037094 1 4.1892e-05 0.0247 0.055794 1 0.0053247 1 4.7208e-07 0.000287 1.3363e-08 8.26e-06 0.0034038 1 0.011615 1 17p loss 45 (14%) 277 0.2494 1 1.2742e-05 0.00761 0.57723 1 0.67707 1 0.63743 1 0.021813 1 0.49224 1 0.44006 1 17q loss 5 (2%) 317 0.20955 1 0.0040175 1 0.11943 1 0.66597 1 0.14826 1 0.38635 1 0.52446 1 0.108 1 18p loss 29 (9%) 293 0.0069972 1 0.024259 1 0.76358 1 0.49232 1 0.57825 1 0.74676 1 0.22539 1 0.65356 1 18q loss 91 (28%) 231 2.1353e-11 1.34e-08 3.1613e-08 1.95e-05 0.28955 1 0.10713 1 0.013355 1 0.44236 1 0.10555 1 0.75007 1 19p loss 27 (8%) 295 0.019841 1 0.11275 1 0.59771 1 0.87457 1 0.11829 1 0.41646 1 0.54928 1 0.48799 1 19q loss 20 (6%) 302 0.031426 1 0.18043 1 0.53134 1 0.51911 1 0.69431 1 0.83272 1 0.2771 1 0.81352 1 20p loss 21 (7%) 301 0.054379 1 0.31927 1 0.51783 1 0.81478 1 0.22385 1 0.090392 1 0.33251 1 0.20391 1 20q loss 10 (3%) 312 0.038898 1 0.21225 1 0.63753 1 0.60102 1 0.035931 1 0.046799 1 0.51193 1 0.65864 1 21q loss 57 (18%) 265 3.9073e-06 0.00236 0.010851 1 0.91955 1 0.31787 1 0.8923 1 0.51213 1 0.18079 1 0.21263 1 22q loss 25 (8%) 297 3.092e-06 0.00187 0.030467 1 0.39622 1 1 1 0.39131 1 0.77198 1 0.0021294 1 0.8566 1 Xq loss 8 (2%) 314 0.3278 1 0.12184 1 0.19365 1 0.34117 1 0.49882 1 1 1 0.49707 1 0.22103 1