Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.022 0.202 0.343 1.0 -0.542 7.0 8.0 MAP3K8 0.019 0.021 -9999.0 0.0 -9999.0 0.0 0.0 FOS -0.003 0.158 0.313 2.0 -0.538 4.0 6.0 PRKCA 0.018 0.021 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.009 0.083 -9999.0 0.0 -0.673 1.0 1.0 HRAS 0.025 0.013 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.017 0.022 -9999.0 0.0 -9999.0 0.0 0.0 NRAS 0.025 0.013 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.039 0.033 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.007 0.104 -9999.0 0.0 -0.476 3.0 3.0 MAP2K1 0.018 0.044 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.015 0.03 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.007 0.015 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.004 -9999.0 0.0 -0.008 13.0 13.0 MAPK1 -0.026 0.16 -9999.0 0.0 -0.488 7.0 7.0 RAF1 0.007 0.017 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0