		Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	57 (83%)	12	0.84989	1	0.77985	1	0.056067	1	0.45587	1	0.64744	1	0.34442	1	1	1	0.33741	1	1	1
KRAS	38 (55%)	31	0.34215	1	0.17995	1	0.0023343	0.31	0.737	1	0.7644	1	0.0084439	1	0.00083521	0.113	0.29246	1	0.046474	1
TP53	45 (65%)	24	0.00022892	0.0311	0.0013522	0.181	0.2098	1	0.14374	1	0.29429	1	0.2229	1	0.46089	1	0.81229	1	0.28827	1
SMAD4	8 (12%)	61	0.10472	1	0.36144	1	0.91418	1	0.59696	1	0.16958	1	0.63557	1	0.12564	1	0.30921	1	1	1
KIAA1804	9 (13%)	60	0.32197	1	0.5784	1	0.099669	1	0.79456	1	0.47052	1	0.71225	1	0.46933	1	0.80471	1	1	1
FBXW7	9 (13%)	60	0.14789	1	0.096175	1	0.40917	1	0.14829	1	0.85487	1	0.1846	1	0.062625	1	0.80471	1	1	1
NRAS	5 (7%)	64	0.85557	1	1	1	0.67453	1	NA	NA	NA	NA	0.53223	1	0.71584	1	0.096864	1	1	1
TCF7L2	7 (10%)	62	0.883	1	0.68279	1	0.7088	1	0.16935	1	0.46064	1	0.2243	1	0.31463	1	1	1	1	1
PIK3CA	7 (10%)	62	1	1	0.73108	1	0.81433	1	0.3556	1	0.55622	1	0.86626	1	0.58662	1	0.34273	1	0.32777	1
OPCML	6 (9%)	63	0.22842	1	0.097181	1	0.50815	1	0.16935	1	0.6284	1	0.942	1	0.7491	1	1	1	1	1
SMAD2	5 (7%)	64	1	1	1	1	0.28971	1	0.015538	1	0.29067	1	0.36933	1	0.15403	1	1	1	1	1
SPATA8	3 (4%)	66	NA	NA	NA	NA	0.38824	1	NA	NA	NA	NA	0.69356	1	0.43889	1	0.43214	1	0.17605	1
ERBB2	4 (6%)	65	0.54032	1	1	1	0.5764	1	0.056682	1	0.6284	1	0.61407	1	0.60021	1	1	1	1	1
IL1RAPL2	5 (7%)	64	0.61254	1	0.51898	1	0.78529	1	NA	NA	NA	NA	0.47315	1	0.52359	1	0.27254	1	1	1
FAM123B	6 (9%)	63	1	1	0.73108	1	0.46322	1	0.24253	1	0.37544	1	0.35808	1	0.30005	1	1	1	1	1
ZIM3	5 (7%)	64	0.82668	1	0.66769	1	0.43343	1	0.0034184	0.451	0.18543	1	0.44506	1	0.52359	1	0.3874	1	0.27975	1
