Molecular subtypes CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p36.22) 24 (10%) 213 7.552e-06 0.00276 0.06896 1 0.41206 1 0.55652 1 0.042094 1 0.1814 1 Amp Peak 2(1q21.3) 75 (32%) 162 1.2492e-14 5.22e-12 7.5349e-06 0.00276 0.21515 1 0.020274 1 0.00079959 0.257 0.0016418 0.514 Amp Peak 3(1q42.3) 73 (31%) 164 6.7066e-13 2.78e-10 0.00063918 0.208 0.75462 1 0.36101 1 9.6899e-05 0.033 0.005871 1 Amp Peak 4(3q26.31) 67 (28%) 170 1.4476e-05 0.00518 0.030695 1 0.11591 1 0.1419 1 0.15927 1 0.49012 1 Amp Peak 5(5p13.1) 58 (24%) 179 1.1736e-12 4.84e-10 0.020049 1 1 1 0.56103 1 0.031573 1 0.0052468 1 Amp Peak 6(6p21.1) 60 (25%) 177 6.7282e-13 2.78e-10 7.523e-05 0.0259 0.33189 1 0.67761 1 0.041978 1 0.0069018 1 Amp Peak 7(6q12) 42 (18%) 195 7.4818e-08 2.87e-05 0.043893 1 0.50979 1 0.89859 1 0.066925 1 0.017928 1 Amp Peak 8(7p11.2) 96 (41%) 141 3.2624e-11 1.32e-08 0.00052393 0.171 0.54669 1 0.65082 1 0.0043733 1 0.020756 1 Amp Peak 9(7q21.2) 97 (41%) 140 3.6667e-10 1.47e-07 0.013428 1 0.54669 1 0.43311 1 0.022891 1 0.072933 1 Amp Peak 10(8p23.1) 79 (33%) 158 2.2684e-16 9.64e-14 0.96038 1 0.36404 1 0.16522 1 0.55777 1 0.62345 1 Amp Peak 11(8q24.21) 139 (59%) 98 6.3886e-16 2.69e-13 0.00069647 0.226 0.28058 1 0.46435 1 0.083808 1 0.020196 1 Amp Peak 12(9p24.1) 30 (13%) 207 0.79332 1 0.63833 1 0.69808 1 0.15927 1 0.70147 1 0.35278 1 Amp Peak 13(9q34.3) 48 (20%) 189 4.0972e-06 0.00151 0.24095 1 0.74699 1 1 1 0.39448 1 0.3133 1 Amp Peak 14(10q26.13) 45 (19%) 192 5.8244e-05 0.0203 0.011637 1 1 1 1 1 0.44665 1 0.26962 1 Amp Peak 15(11p13) 38 (16%) 199 0.00031529 0.104 0.061998 1 0.69808 1 0.29321 1 0.29326 1 0.070048 1 Amp Peak 16(11q13.3) 47 (20%) 190 1.3461e-06 0.000509 0.053724 1 1 1 0.26386 1 0.010746 1 0.050021 1 Amp Peak 17(12p12.1) 54 (23%) 183 4.4691e-06 0.00164 0.023798 1 0.41206 1 0.55652 1 0.16 1 0.79878 1 Amp Peak 18(12q15) 49 (21%) 188 6.907e-05 0.0238 0.0021919 0.679 0.72051 1 1 1 0.47451 1 0.8036 1 Amp Peak 19(13q12.3) 81 (34%) 156 5.9436e-09 2.33e-06 0.0025724 0.79 0.22314 1 0.11529 1 0.40816 1 0.15094 1 Amp Peak 20(13q22.1) 88 (37%) 149 1.999e-08 7.76e-06 0.004822 1 0.13084 1 0.65181 1 0.32341 1 0.00077724 0.251 Amp Peak 21(15q26.1) 52 (22%) 185 1.956e-14 8.16e-12 0.00011765 0.0398 1 1 0.88507 1 0.024062 1 0.013245 1 Amp Peak 22(17q12) 61 (26%) 176 7.7395e-12 3.17e-09 0.039542 1 0.73604 1 0.16166 1 0.0088044 1 0.0036189 1 Amp Peak 23(18q11.2) 61 (26%) 176 8.7674e-07 0.000332 0.0096275 1 1 1 0.61561 1 0.33841 1 0.16432 1 Amp Peak 24(19q12) 61 (26%) 176 6.2628e-10 2.5e-07 0.00044888 0.147 0.50979 1 0.060358 1 0.013821 1 1.133e-05 0.00409 Amp Peak 25(20q13.2) 147 (62%) 90 9.2311e-20 3.95e-17 8.7274e-06 0.00318 0.75462 1 0.11648 1 0.031477 1 0.023879 1 Amp Peak 26(Xq27.3) 43 (18%) 194 1.8219e-06 0.000685 0.18136 1 0.45655 1 0.67439 1 0.039613 1 0.61701 1 Del Peak 1(1p36.11) 63 (27%) 174 2.707e-12 1.11e-09 0.0052846 1 0.35798 1 0.53759 1 0.069801 1 0.011841 1 Del Peak 2(1p31.1) 37 (16%) 200 7.7789e-10 3.1e-07 0.19137 1 0.69808 1 0.64102 1 0.24074 1 0.031088 1 Del Peak 3(1q44) 14 (6%) 223 0.24783 1 0.13672 1 0.41206 1 0.83965 1 0.20854 1 0.061731 1 Del Peak 4(2q32.1) 28 (12%) 209 0.0033272 1 0.47295 1 0.66403 1 0.72994 1 0.27886 1 0.061364 1 Del Peak 5(2q33.3) 23 (10%) 214 0.0012275 0.392 0.39039 1 0.48837 1 NA NA 0.69571 1 0.23577 1 Del Peak 6(2q37.2) 33 (14%) 204 1.5892e-05 0.00567 0.049138 1 0.60692 1 0.64265 1 0.11383 1 0.008889 1 Del Peak 7(3p26.1) 56 (24%) 181 2.4911e-10 1e-07 0.0012517 0.398 0.31015 1 0.21026 1 0.03865 1 0.0027181 0.829 Del Peak 8(3p14.2) 71 (30%) 166 1.9038e-11 7.75e-09 0.0046755 1 0.48761 1 0.13786 1 0.20507 1 0.013841 1 Del Peak 9(3q26.31) 20 (8%) 217 1.4187e-05 0.00509 0.013519 1 0.34487 1 0.35593 1 0.059945 1 0.0065904 1 Del Peak 10(4p16.3) 76 (32%) 161 4.9795e-12 2.04e-09 2.7317e-05 0.00964 0.34747 1 0.36101 1 0.0010511 0.337 1.5044e-06 0.000567 Del Peak 11(4q22.1) 91 (38%) 146 2.0073e-20 8.61e-18 1.38e-05 0.00497 0.22314 1 0.54349 1 0.0033435 1 0.00020491 0.0682 Del Peak 12(4q35.1) 87 (37%) 150 8.7836e-18 3.74e-15 6.7789e-05 0.0235 0.066585 1 0.49828 1 0.015808 1 0.00018804 0.063 Del Peak 13(5q11.2) 70 (30%) 167 4.2658e-19 1.82e-16 4.6422e-09 1.83e-06 0.045209 1 0.14976 1 2.2719e-05 0.00804 4.0518e-06 0.0015 Del Peak 14(6p25.3) 48 (20%) 189 2.0465e-07 7.82e-05 0.052421 1 0.69808 1 0.42391 1 0.28028 1 0.00029289 0.0967 Del Peak 15(6q26) 47 (20%) 190 9.4377e-06 0.00342 0.015402 1 0.45655 1 0.60269 1 0.22263 1 0.16146 1 Del Peak 16(6q27) 47 (20%) 190 2.4391e-06 0.000912 0.012373 1 0.24044 1 0.29321 1 0.53184 1 0.039348 1 Del Peak 17(7q31.1) 26 (11%) 211 4.8424e-06 0.00178 0.016308 1 0.41206 1 0.55652 1 0.030548 1 0.083854 1 Del Peak 18(7q36.3) 42 (18%) 195 2.5395e-10 1.02e-07 0.0012972 0.411 0.69808 1 0.49912 1 0.17944 1 0.0016965 0.529 Del Peak 19(8p23.2) 56 (24%) 181 8.789e-14 3.65e-11 6.6478e-05 0.0231 0.50979 1 0.89859 1 0.047351 1 0.00017717 0.0595 Del Peak 20(9p23) 90 (38%) 147 5.7789e-16 2.44e-13 0.0026957 0.825 0.12426 1 0.44922 1 0.033106 1 0.026195 1 Del Peak 21(9p21.3) 88 (37%) 149 3.4625e-16 1.47e-13 1.6283e-08 6.33e-06 0.21515 1 0.83869 1 0.0066167 1 0.0024305 0.751 Del Peak 22(9q21.11) 52 (22%) 185 2.6546e-08 1.02e-05 0.0087911 1 0.69808 1 0.64102 1 0.081703 1 0.0024815 0.764 Del Peak 23(10p14) 34 (14%) 203 3.3972e-07 0.000129 0.0019864 0.618 0.72051 1 0.88507 1 0.016654 1 0.045935 1 Del Peak 24(10q22.3) 34 (14%) 203 2.2566e-08 8.73e-06 0.016519 1 0.13239 1 0.15048 1 0.019372 1 0.0015599 0.49 Del Peak 25(10q23.31) 54 (23%) 183 2.1655e-14 9.01e-12 0.0013305 0.42 0.0068449 1 0.089908 1 8.965e-05 0.0307 4.6912e-05 0.0165 Del Peak 26(11p15.5) 46 (19%) 191 2.2264e-09 8.79e-07 0.0040018 1 1 1 1 1 0.18041 1 0.0048163 1 Del Peak 27(11q23.2) 43 (18%) 194 0.00024456 0.081 0.0002021 0.0675 1 1 0.21463 1 0.060725 1 0.22129 1 Del Peak 28(12p13.2) 34 (14%) 203 5.3004e-09 2.08e-06 0.013688 1 1 1 1 1 0.033707 1 0.2217 1 Del Peak 29(14q21.1) 52 (22%) 185 3.9484e-06 0.00146 0.11801 1 0.13239 1 0.67439 1 0.034287 1 0.017706 1 Del Peak 30(14q32.33) 59 (25%) 178 1.8794e-06 0.000705 0.21932 1 0.088339 1 0.4576 1 0.25067 1 0.17404 1 Del Peak 31(15q11.2) 56 (24%) 181 1.014e-11 4.14e-09 0.00013804 0.0465 0.0093419 1 0.010985 1 0.010034 1 0.0001066 0.0362 Del Peak 32(15q15.1) 57 (24%) 180 2.6335e-10 1.06e-07 0.00066115 0.215 0.045209 1 0.089908 1 0.035369 1 5.9551e-05 0.0207 Del Peak 33(16p13.3) 34 (14%) 203 3.7573e-06 0.0014 0.25221 1 0.66403 1 0.72994 1 0.0071118 1 0.12717 1 Del Peak 34(16q23.1) 74 (31%) 163 1.7927e-05 0.00638 0.68803 1 0.54337 1 0.91536 1 0.66532 1 0.18215 1 Del Peak 35(17p12) 79 (33%) 158 6.7954e-23 2.92e-20 2.5105e-06 0.000936 0.20275 1 0.50906 1 0.0014182 0.447 2.0086e-05 0.00713 Del Peak 36(17q24.3) 36 (15%) 201 2.572e-08 9.93e-06 0.22725 1 0.088339 1 0.055065 1 0.014457 1 0.0011503 0.368 Del Peak 37(18q21.2) 95 (40%) 142 5.1019e-16 2.16e-13 0.014402 1 0.76349 1 0.19112 1 0.11159 1 0.014249 1 Del Peak 38(18q22.3) 92 (39%) 145 8.5106e-16 3.57e-13 0.013339 1 1 1 0.9173 1 0.087003 1 0.036344 1 Del Peak 39(19p13.3) 71 (30%) 166 2.4591e-25 1.06e-22 7.5666e-09 2.96e-06 0.34747 1 0.36101 1 8.9338e-05 0.0306 1.5457e-09 6.12e-07 Del Peak 40(19q13.11) 30 (13%) 207 8.5411e-10 3.39e-07 4.9934e-05 0.0175 0.094572 1 0.22978 1 0.0035446 1 5.2174e-05 0.0183 Del Peak 41(20p12.1) 33 (14%) 204 9.1827e-06 0.00333 0.0001125 0.0381 1 1 0.83965 1 0.024356 1 0.015975 1 Del Peak 42(21q11.2) 73 (31%) 164 2.8986e-11 1.18e-08 0.0034726 1 0.33189 1 0.67761 1 0.011543 1 0.27471 1 Del Peak 43(22q13.31) 70 (30%) 167 7.5253e-15 3.15e-12 1.1448e-08 4.46e-06 1 1 1 1 0.0030447 0.926 0.00020955 0.0696 Del Peak 44(Xp22.2) 38 (16%) 199 3.9622e-08 1.52e-05 0.014757 1 0.69808 1 0.73203 1 0.13075 1 0.0083929 1 Del Peak 45(Xp21.1) 33 (14%) 204 1.0936e-10 4.42e-08 0.085444 1 0.28058 1 0.28273 1 0.020849 1 0.076217 1 Del Peak 46(Xq21.33) 30 (13%) 207 3.6761e-07 0.00014 0.066334 1 0.45655 1 0.67439 1 0.049573 1 0.010772 1