Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.002 0.181 -9999.0 0.0 -0.602 2.0 2.0 MAP3K8 0.023 0.076 -9999.0 0.0 -0.467 1.0 1.0 FOS -0.015 0.174 -9999.0 0.0 -0.621 2.0 2.0 PRKCA 0.035 0.013 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.021 0.077 -9999.0 0.0 -0.466 1.0 1.0 HRAS 0.034 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.034 0.014 -9999.0 0.0 -9999.0 0.0 0.0 NRAS 0.035 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.056 0.031 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.019 0.188 -9999.0 0.0 -0.54 4.0 4.0 MAP2K1 0.006 0.105 -9999.0 0.0 -0.574 1.0 1.0 ELK1 0.035 0.015 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.021 0.046 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 1.0 1.0 MAPK1 -0.023 0.193 -9999.0 0.0 -0.576 4.0 4.0 RAF1 0.023 0.046 -9999.0 0.0 -0.243 1.0 1.0 KRAS 0.034 0.011 -9999.0 0.0 -9999.0 0.0 0.0