Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 16 (11%) 134 0.0030324 1 0.17214 1 0.4661 1 0.74432 1 0.5185 1 0.38562 1 0.20167 1 0.25952 1 1q gain 32 (21%) 118 0.12704 1 0.47755 1 0.94061 1 0.63731 1 0.82168 1 0.65533 1 0.46285 1 0.70755 1 2p gain 28 (19%) 122 0.00011082 0.0617 0.0010228 0.557 0.21375 1 0.63731 1 0.28241 1 0.73848 1 0.057101 1 0.07208 1 2q gain 11 (7%) 139 0.058959 1 0.24148 1 0.6896 1 0.60471 1 0.34214 1 0.35869 1 0.18206 1 0.18713 1 3p gain 30 (20%) 120 3.509e-06 0.00198 0.044697 1 0.028711 1 0.014554 1 0.090936 1 0.0050015 1 0.025403 1 0.079318 1 3q gain 42 (28%) 108 0.00055894 0.308 0.2644 1 1 1 0.14212 1 0.58633 1 0.085692 1 0.21871 1 0.13381 1 4p gain 8 (5%) 142 0.44332 1 0.62452 1 1 1 1 1 1 1 0.6133 1 0.51974 1 0.386 1 4q gain 3 (2%) 147 0.29643 1 0.40509 1 NA NA NA NA 0.78228 1 0.72698 1 0.32557 1 0.16274 1 5p gain 40 (27%) 110 0.08621 1 0.40206 1 0.028686 1 0.43569 1 0.35401 1 0.60097 1 0.22045 1 0.33004 1 5q gain 18 (12%) 132 0.090344 1 0.076924 1 0.22843 1 0.26132 1 0.70326 1 1 1 0.12219 1 0.33019 1 6p gain 8 (5%) 142 0.54496 1 0.18241 1 NA NA NA NA 1 1 0.22693 1 0.46241 1 0.16862 1 6q gain 5 (3%) 145 0.40231 1 0.38169 1 NA NA NA NA NA NA NA NA 0.11473 1 0.13054 1 7p gain 46 (31%) 104 0.0018774 1 0.0017241 0.931 0.83509 1 0.21142 1 0.96821 1 0.96295 1 0.017498 1 0.25679 1 7q gain 43 (29%) 107 0.0024946 1 0.050446 1 1 1 0.25837 1 0.96754 1 0.89057 1 0.40667 1 0.31087 1 8p gain 15 (10%) 135 0.10361 1 0.0033968 1 0.19229 1 0.25214 1 0.077555 1 1 1 0.53706 1 1 1 8q gain 39 (26%) 111 0.052333 1 0.088746 1 0.62304 1 0.45906 1 0.27836 1 0.88929 1 0.53265 1 0.88828 1 9p gain 15 (10%) 135 0.0033624 1 0.43663 1 0.18861 1 1 1 0.5185 1 0.098667 1 0.04336 1 0.89365 1 9q gain 11 (7%) 139 0.49401 1 0.32308 1 0.09789 1 0.66711 1 0.055614 1 0.03805 1 0.71681 1 0.71008 1 10p gain 28 (19%) 122 0.0011391 0.617 0.001915 1 0.38191 1 0.016951 1 0.52301 1 0.65128 1 0.38801 1 0.16198 1 10q gain 7 (5%) 143 0.34123 1 0.18804 1 0.51237 1 0.29442 1 0.55291 1 0.16366 1 0.61025 1 0.76889 1 11p gain 8 (5%) 142 0.050713 1 0.95649 1 NA NA NA NA 0.72441 1 1 1 0.32322 1 0.49016 1 11q gain 8 (5%) 142 0.24705 1 0.51769 1 NA NA NA NA 0.48279 1 0.35975 1 0.51974 1 0.386 1 12p gain 24 (16%) 126 0.0037783 1 0.62431 1 0.12992 1 0.19136 1 0.91391 1 0.49266 1 0.25244 1 0.77455 1 12q gain 17 (11%) 133 0.013898 1 0.30828 1 0.41907 1 0.55065 1 0.40861 1 0.75901 1 0.022613 1 0.23265 1 13q gain 25 (17%) 125 0.2181 1 0.8848 1 0.031759 1 0.084378 1 0.044184 1 0.045172 1 0.27355 1 0.66661 1 14q gain 11 (7%) 139 0.090272 1 0.8977 1 0.20595 1 0.57589 1 0.27781 1 0.17588 1 0.7025 1 0.69198 1 15q gain 5 (3%) 145 0.03821 1 0.031388 1 0.29599 1 0.32754 1 0.68264 1 1 1 1 1 1 1 16p gain 10 (7%) 140 0.049859 1 0.6091 1 0.63787 1 1 1 0.75115 1 0.71718 1 0.61768 1 1 1 16q gain 13 (9%) 137 0.0042973 1 0.26582 1 1 1 1 1 1 1 0.2557 1 0.73906 1 0.73338 1 17p gain 9 (6%) 141 0.19318 1 0.55098 1 NA NA NA NA 0.72441 1 0.54474 1 0.51974 1 0.386 1 17q gain 25 (17%) 125 0.00038347 0.212 0.010316 1 0.49688 1 0.16783 1 0.023256 1 0.10759 1 0.12379 1 0.10702 1 18p gain 26 (17%) 124 4.8955e-06 0.00276 0.22066 1 0.9333 1 0.25366 1 0.06519 1 0.57862 1 0.38347 1 0.084829 1 18q gain 9 (6%) 141 0.033055 1 0.59851 1 0.46507 1 0.083649 1 0.4311 1 0.28944 1 0.80828 1 0.49016 1 19p gain 15 (10%) 135 0.033064 1 0.058455 1 NA NA NA NA 0.10931 1 0.48909 1 0.32022 1 0.60999 1 19q gain 29 (19%) 121 0.00070008 0.384 0.11698 1 0.6325 1 1 1 0.046694 1 0.10528 1 0.31897 1 0.74998 1 20p gain 54 (36%) 96 0.033464 1 0.077142 1 0.41527 1 0.80463 1 0.47508 1 0.15112 1 0.40256 1 0.47663 1 20q gain 59 (39%) 91 0.020644 1 0.05109 1 0.43936 1 0.49442 1 0.07747 1 0.087981 1 0.026477 1 0.21365 1 21q gain 27 (18%) 123 0.0018655 1 0.0011049 0.601 0.59828 1 0.5386 1 0.19126 1 0.1023 1 0.27515 1 0.15234 1 22q gain 12 (8%) 138 0.000744 0.407 0.16458 1 0.53575 1 0.57199 1 0.45056 1 0.90252 1 0.021277 1 1 1 Xq gain 6 (4%) 144 0.11267 1 0.80129 1 NA NA NA NA 0.76338 1 1 1 1 1 1 1 1p loss 4 (3%) 146 0.45572 1 0.050893 1 NA NA NA NA NA NA NA NA 0.35826 1 0.22918 1 2p loss 8 (5%) 142 0.82789 1 0.02291 1 NA NA NA NA 0.36811 1 0.16366 1 1 1 1 1 2q loss 17 (11%) 133 0.011189 1 0.47174 1 1 1 0.29442 1 0.4629 1 0.032343 1 0.75641 1 0.5717 1 3p loss 9 (6%) 141 0.063331 1 0.77287 1 0.34475 1 0.4667 1 0.085845 1 0.071884 1 0.1752 1 0.15681 1 4p loss 29 (19%) 121 0.00073887 0.405 0.29172 1 0.85302 1 0.76733 1 0.42513 1 0.34163 1 0.535 1 0.74998 1 4q loss 26 (17%) 124 0.077748 1 0.78022 1 0.67965 1 0.70858 1 0.59268 1 0.60125 1 0.72636 1 0.21002 1 5p loss 14 (9%) 136 0.00060734 0.334 0.6093 1 0.51704 1 0.86705 1 0.53222 1 0.72064 1 0.44241 1 0.58851 1 5q loss 36 (24%) 114 0.0011231 0.61 0.092333 1 0.76662 1 0.90556 1 0.8953 1 0.772 1 0.42646 1 0.30844 1 6p loss 18 (12%) 132 0.051694 1 0.23761 1 0.23336 1 0.45564 1 0.38443 1 0.8123 1 0.65316 1 0.90422 1 6q loss 29 (19%) 121 6.0493e-06 0.0034 0.0088271 1 0.24675 1 0.80167 1 0.26038 1 0.047743 1 0.77365 1 1 1 7q loss 3 (2%) 147 0.3754 1 0.2924 1 NA NA NA NA NA NA NA NA 0.23281 1 0.26281 1 8p loss 49 (33%) 101 6.3969e-07 0.000362 3.0772e-05 0.0172 0.14267 1 0.28713 1 0.64311 1 0.4405 1 0.0071962 1 0.0027731 1 8q loss 5 (3%) 145 0.28492 1 0.19193 1 NA NA NA NA 0.78228 1 1 1 0.15053 1 0.019146 1 9p loss 43 (29%) 107 0.00020006 0.111 0.0065168 1 0.037356 1 0.36287 1 0.034134 1 0.00081284 0.444 0.89411 1 0.61175 1 9q loss 41 (27%) 109 7.8247e-05 0.0437 0.005446 1 0.001208 0.654 0.0083329 1 0.0027444 1 0.00011491 0.0639 0.84105 1 0.7185 1 10p loss 19 (13%) 131 0.76299 1 0.8782 1 0.18861 1 0.52816 1 0.25174 1 0.275 1 0.29053 1 0.069099 1 10q loss 30 (20%) 120 0.11818 1 0.053763 1 0.92133 1 0.84318 1 0.20859 1 0.040607 1 0.047541 1 0.010437 1 11p loss 48 (32%) 102 1.3616e-06 0.000769 0.0019012 1 0.23202 1 0.66244 1 0.073907 1 0.0024832 1 0.17765 1 0.72778 1 11q loss 35 (23%) 115 0.00018792 0.104 0.029811 1 0.3002 1 0.55563 1 0.21099 1 0.42423 1 0.27585 1 0.6778 1 12p loss 6 (4%) 144 0.15909 1 0.16112 1 NA NA NA NA 0.32493 1 0.28446 1 0.66558 1 1 1 12q loss 9 (6%) 141 0.15867 1 1 1 NA NA NA NA 0.15025 1 0.35975 1 0.40452 1 0.52571 1 13q loss 20 (13%) 130 0.015746 1 0.31107 1 0.10353 1 0.14141 1 0.11089 1 0.41842 1 0.7106 1 0.3692 1 14q loss 25 (17%) 125 0.00037396 0.207 0.027225 1 0.81766 1 0.31672 1 0.74575 1 0.47021 1 0.039025 1 0.18057 1 15q loss 19 (13%) 131 0.16825 1 0.094986 1 0.12078 1 0.41094 1 0.077555 1 0.057567 1 0.19177 1 0.015563 1 16p loss 17 (11%) 133 0.01789 1 0.27557 1 0.6034 1 1 1 0.34313 1 0.86361 1 0.15836 1 0.0021656 1 16q loss 17 (11%) 133 0.0047746 1 0.3993 1 0.74957 1 1 1 0.73473 1 0.80619 1 0.71244 1 0.013221 1 17p loss 42 (28%) 108 0.0020831 1 0.10811 1 0.54073 1 0.80463 1 0.0062607 1 0.16064 1 0.05165 1 0.035004 1 17q loss 6 (4%) 144 0.71977 1 0.039355 1 NA NA NA NA 0.85704 1 0.8447 1 0.235 1 0.52657 1 18p loss 22 (15%) 128 0.004995 1 0.033528 1 0.50728 1 0.58438 1 1 1 0.17159 1 0.45981 1 0.0093524 1 18q loss 39 (26%) 111 1.5386e-05 0.00863 0.70891 1 0.81334 1 0.18904 1 0.18208 1 0.5589 1 0.42002 1 0.1557 1 19p loss 9 (6%) 141 0.29996 1 0.93289 1 0.25229 1 0.14046 1 0.41537 1 0.35616 1 0.44477 1 0.073747 1 19q loss 4 (3%) 146 0.54538 1 0.70202 1 NA NA NA NA 0.48026 1 0.72698 1 0.14823 1 0.14401 1 20p loss 7 (5%) 143 0.31279 1 0.25113 1 NA NA NA NA 1 1 1 1 0.68975 1 0.05772 1 21q loss 17 (11%) 133 0.55556 1 0.53304 1 0.4661 1 0.21582 1 0.6739 1 0.58428 1 0.84763 1 0.26656 1 22q loss 29 (19%) 121 6.2976e-05 0.0352 0.66937 1 0.070593 1 0.12643 1 0.068631 1 0.12033 1 0.77029 1 0.013814 1 Xq loss 4 (3%) 146 0.25181 1 0.28538 1 NA NA NA NA 0.48026 1 0.5623 1 0.6891 1 0.65934 1